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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 4
1990 3
1991 9
1992 14
1993 12
1994 14
1995 12
1996 15
1997 12
1998 17
1999 22
2000 18
2001 14
2002 25
2003 26
2004 15
2005 20
2006 21
2007 20
2008 26
2009 25
2010 26
2011 38
2012 41
2013 28
2014 21
2015 25
2016 26
2017 30
2018 27
2019 29
2020 30
2021 7
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630 results
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Page 1
Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.
Yokoda RT, Carey EJ. Yokoda RT, et al. Am J Gastroenterol. 2019 Oct;114(10):1593-1605. doi: 10.14309/ajg.0000000000000268. Am J Gastroenterol. 2019. PMID: 31169523 Review.
Cholestatic liver diseases encompass a broad spectrum of pathologies, with the core injury occurring at the level of cholangiocytes and progressing to hepatic fibrosis and liver dysfunction. Primary biliary cholangitis and primary sclerosing cholang …
Cholestatic liver diseases encompass a broad spectrum of pathologies, with the core injury occurring at the level of cholangiocytes and prog …
Primary Sclerosing Cholangitis.
Lazaridis KN, LaRusso NF. Lazaridis KN, et al. N Engl J Med. 2016 Sep 22;375(12):1161-70. doi: 10.1056/NEJMra1506330. N Engl J Med. 2016. PMID: 27653566 Free PMC article. Review. No abstract available.
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.
Eaton JE, Talwalkar JA, Lazaridis KN, Gores GJ, Lindor KD. Eaton JE, et al. Gastroenterology. 2013 Sep;145(3):521-36. doi: 10.1053/j.gastro.2013.06.052. Epub 2013 Jul 1. Gastroenterology. 2013. PMID: 23827861 Free PMC article. Review.
Primary sclerosing cholangitis (PSC), first described in the mid-1850s, is a complex liver disease that is heterogeneous in its presentation. ...
Primary sclerosing cholangitis (PSC), first described in the mid-1850s, is a complex liver disease that is heterogeneou …
norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
Fickert P, Hirschfield GM, Denk G, Marschall HU, Altorjay I, Färkkilä M, Schramm C, Spengler U, Chapman R, Bergquist A, Schrumpf E, Nevens F, Trivedi P, Reiter FP, Tornai I, Halilbasic E, Greinwald R, Pröls M, Manns MP, Trauner M; European PSC norUDCA Study Group. Fickert P, et al. J Hepatol. 2017 Sep;67(3):549-558. doi: 10.1016/j.jhep.2017.05.009. Epub 2017 May 18. J Hepatol. 2017. PMID: 28529147 Free article. Clinical Trial.
BACKGROUND & AIM: Primary sclerosing cholangitis (PSC) represents a devastating bile duct disease, currently lacking effective medical therapy. 24-norursodeoxycholic acid (norUDCA) is a side chain-shortened C(23) homologue of UDCA and has shown pot …
BACKGROUND & AIM: Primary sclerosing cholangitis (PSC) represents a devastating bile duct disease, currently lackin …
Autoimmune Hepatitis, Sclerosing Cholangitis, and Autoimmune Sclerosing Cholangitis or Overlap Syndrome.
Kerkar N, Chan A. Kerkar N, et al. Clin Liver Dis. 2018 Nov;22(4):689-702. doi: 10.1016/j.cld.2018.06.005. Clin Liver Dis. 2018. PMID: 30266157 Review.
There is inflammation of the intrahepatic and/or extrahepatic bile ducts in Sclerosing cholangitis (SC) and when associated with inflammatory bowel disease, it is known as primary SC, with Ursodeoxycholic acid used for therapy. The overlap of cl …
There is inflammation of the intrahepatic and/or extrahepatic bile ducts in Sclerosing cholangitis (SC) and when associated wi …
ACG Clinical Guideline: Primary Sclerosing Cholangitis.
Lindor KD, Kowdley KV, Harrison ME; American College of Gastroenterology. Lindor KD, et al. Am J Gastroenterol. 2015 May;110(5):646-59; quiz 660. doi: 10.1038/ajg.2015.112. Epub 2015 Apr 14. Am J Gastroenterol. 2015. PMID: 25869391
Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. The cause is unknown, although it is commonly associated with colitis. There is no approved or proven therapy, although ursod …
Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver trans …
The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS-9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis.
Trauner M, Gulamhusein A, Hameed B, Caldwell S, Shiffman ML, Landis C, Eksteen B, Agarwal K, Muir A, Rushbrook S, Lu X, Xu J, Chuang JC, Billin AN, Li G, Chung C, Subramanian GM, Myers RP, Bowlus CL, Kowdley KV. Trauner M, et al. Hepatology. 2019 Sep;70(3):788-801. doi: 10.1002/hep.30509. Epub 2019 Mar 10. Hepatology. 2019. PMID: 30661255 Free PMC article. Clinical Trial.
Primary sclerosing cholangitis (PSC) represents a major unmet medical need. ...Overall, 52 patients were randomized (median age 43 years, 58% male, 60% with inflammatory bowel disease, 46% on ursodeoxycholic acid). Baseline median serum ALP and …
Primary sclerosing cholangitis (PSC) represents a major unmet medical need. ...Overall, 52 patients were randomized (me …
Novel and emerging therapies for cholestatic liver diseases.
Goldstein J, Levy C. Goldstein J, et al. Liver Int. 2018 Sep;38(9):1520-1535. doi: 10.1111/liv.13880. Epub 2018 Jun 14. Liver Int. 2018. PMID: 29758112 Review.
By altering or overwhelming these defence mechanisms, cholestatic diseases such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) can further progress to biliary cirrhosis, end-stage liver disease and death or liver t …
By altering or overwhelming these defence mechanisms, cholestatic diseases such as primary biliary cholangitis (PBC) and pr …
The ascending pathophysiology of cholestatic liver disease.
Jansen PL, Ghallab A, Vartak N, Reif R, Schaap FG, Hampe J, Hengstler JG. Jansen PL, et al. Hepatology. 2017 Feb;65(2):722-738. doi: 10.1002/hep.28965. Hepatology. 2017. PMID: 27981592 Review.
In this review we develop the argument that cholestatic liver diseases, particularly primary biliary cholangitis and primary sclerosing cholangitis (PSC), evolve over time with anatomically an ascending course of the disease process. ...Anti-inf …
In this review we develop the argument that cholestatic liver diseases, particularly primary biliary cholangitis and primar …
Imaging Features of Primary Sclerosing Cholangitis: From Diagnosis to Liver Transplant Follow-up.
Khoshpouri P, Habibabadi RR, Hazhirkarzar B, Ameli S, Ghadimi M, Ghasabeh MA, Menias CO, Kim A, Li Z, Kamel IR. Khoshpouri P, et al. Radiographics. 2019 Nov-Dec;39(7):1938-1964. doi: 10.1148/rg.2019180213. Epub 2019 Oct 18. Radiographics. 2019. PMID: 31626561 Review.
Primary sclerosing cholangitis (PSC) is a chronic progressive inflammatory disease of the bile ducts that leads to multifocal bile duct fibrosis, strictures, cholestasis, liver parenchymal changes, and ultimately cirrhosis. ...MR cholangiopancreatography and …
Primary sclerosing cholangitis (PSC) is a chronic progressive inflammatory disease of the bile ducts that leads to mult …
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