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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1959 1
1960 4
1961 2
1962 4
1963 6
1964 7
1965 5
1966 8
1967 8
1968 9
1969 11
1970 8
1971 16
1972 18
1973 28
1974 27
1975 84
1976 71
1977 98
1978 129
1979 148
1980 222
1981 249
1982 347
1983 339
1984 378
1985 435
1986 468
1987 471
1988 530
1989 511
1990 669
1991 748
1992 900
1993 971
1994 1198
1995 1231
1996 1268
1997 1305
1998 1305
1999 1197
2000 1331
2001 1275
2002 1220
2003 1255
2004 1262
2005 1212
2006 1207
2007 1352
2008 1337
2009 1323
2010 1383
2011 1449
2012 1429
2013 1558
2014 1506
2015 1521
2016 1344
2017 1407
2018 1286
2019 1291
2020 1284
2021 96
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Search Results

40,908 results
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Page 1
All trans retinoic acid and cancer.
Siddikuzzaman, Guruvayoorappan C, Berlin Grace VM. Siddikuzzaman, et al. Immunopharmacol Immunotoxicol. 2011 Jun;33(2):241-9. doi: 10.3109/08923973.2010.521507. Epub 2010 Oct 8. Immunopharmacol Immunotoxicol. 2011. PMID: 20929432 Review.
All-trans retinoic acid (ATRA) is an active metabolite of vitamin A under the family retinoid. ...Differentiation therapy with ATRA has marked a major advance and become the first choice drug in the treatment of acute promyelocytic leukemia (APL). Conversions of 13- …
All-trans retinoic acid (ATRA) is an active metabolite of vitamin A under the family retinoid. ...Differentiation therapy with …
Retinoic acid signaling pathways.
Ghyselinck NB, Duester G. Ghyselinck NB, et al. Development. 2019 Jul 4;146(13):dev167502. doi: 10.1242/dev.167502. Development. 2019. PMID: 31273085 Free PMC article. Review.
Retinoic acid (RA), a metabolite of retinol (vitamin A), functions as a ligand for nuclear RA receptors (RARs) that regulate development of chordate animals. ...
Retinoic acid (RA), a metabolite of retinol (vitamin A), functions as a ligand for nuclear RA receptors (RARs) that regulate d …
Retinoic acid signaling and neuronal differentiation.
Janesick A, Wu SC, Blumberg B. Janesick A, et al. Cell Mol Life Sci. 2015 Apr;72(8):1559-76. doi: 10.1007/s00018-014-1815-9. Epub 2015 Jan 6. Cell Mol Life Sci. 2015. PMID: 25558812 Free article. Review.
The identification of neurological symptoms caused by vitamin A deficiency pointed to a critical, early developmental role of vitamin A and its metabolite, retinoic acid (RA). The ability of RA to induce post-mitotic, neural phenotypes in various stem cells, in vitr …
The identification of neurological symptoms caused by vitamin A deficiency pointed to a critical, early developmental role of vitamin A and …
The success and the challenge of all-trans retinoic acid in the treatment of cancer.
Ni X, Hu G, Cai X. Ni X, et al. Crit Rev Food Sci Nutr. 2019;59(sup1):S71-S80. doi: 10.1080/10408398.2018.1509201. Epub 2018 Oct 2. Crit Rev Food Sci Nutr. 2019. PMID: 30277803 Review.
All-trans retinoic acid (ATRA), an active metabolite of vitamin A, plays important roles in cell proliferation, cell differentiation, apoptosis, and embryonic development. ...
All-trans retinoic acid (ATRA), an active metabolite of vitamin A, plays important roles in cell proliferation, cell different …
Retinoic Acid and Retinoic Acid Receptors as Pleiotropic Modulators of the Immune System.
Larange A, Cheroutre H. Larange A, et al. Annu Rev Immunol. 2016 May 20;34:369-94. doi: 10.1146/annurev-immunol-041015-055427. Annu Rev Immunol. 2016. PMID: 27168242 Review.
This is especially key at the intestinal border, where dietary vitamin A is first absorbed. Most effects of vitamin A are exerted by its metabolite, retinoic acid (RA), which through ligation of nuclear receptors controls transcriptional expression of RA target gene …
This is especially key at the intestinal border, where dietary vitamin A is first absorbed. Most effects of vitamin A are exerted by its met …
Gene expression regulation by retinoic acid.
Balmer JE, Blomhoff R. Balmer JE, et al. J Lipid Res. 2002 Nov;43(11):1773-808. doi: 10.1194/jlr.r100015-jlr200. J Lipid Res. 2002. PMID: 12401878 Free article. Review.
Over the last quarter century, more than 532 genes have been put forward as regulatory targets of retinoic acid. In some cases this control is direct, driven by a liganded heterodimer of retinoid receptors bound to a DNA response element; in others, it is indirect, …
Over the last quarter century, more than 532 genes have been put forward as regulatory targets of retinoic acid. In some cases …
Generation of Retinaldehyde for Retinoic Acid Biosynthesis.
Belyaeva OV, Adams MK, Popov KM, Kedishvili NY. Belyaeva OV, et al. Biomolecules. 2019 Dec 18;10(1):5. doi: 10.3390/biom10010005. Biomolecules. 2019. PMID: 31861321 Free PMC article. Review.
Either too little or too much of retinoic acid in developing or adult tissues is equally harmful. All-trans-retinoic acid is produced by the irreversible oxidation of all-trans-retinaldehyde. Thus, the concentration of retinaldehyde as the immediate pr …
Either too little or too much of retinoic acid in developing or adult tissues is equally harmful. All-trans-retinoic …
Retinoic acid in the development, regeneration and maintenance of the nervous system.
Maden M. Maden M. Nat Rev Neurosci. 2007 Oct;8(10):755-65. doi: 10.1038/nrn2212. Nat Rev Neurosci. 2007. PMID: 17882253 Review.
Retinoic acid (RA) is involved in the induction of neural differentiation, motor axon outgrowth and neural patterning. ...
Retinoic acid (RA) is involved in the induction of neural differentiation, motor axon outgrowth and neural patterning. ...
Retinoic acid inhibits neuronal voltage-gated calcium channels.
de Hoog E, Lukewich MK, Spencer GE. de Hoog E, et al. Cell Calcium. 2018 Jun;72:51-61. doi: 10.1016/j.ceca.2018.02.001. Epub 2018 Feb 13. Cell Calcium. 2018. PMID: 29748133
Retinoic acid is the active metabolite of vitamin A and regulates several important cellular processes by activating retinoic acid receptors (RAR) and retinoid X receptors (RXR). ...Retinoic acid can thus affect Ca(2+) signaling and can p …
Retinoic acid is the active metabolite of vitamin A and regulates several important cellular processes by activating retino …
Retinoic acid and the ocular surface.
Samarawickrama C, Chew S, Watson S. Samarawickrama C, et al. Surv Ophthalmol. 2015 May-Jun;60(3):183-95. doi: 10.1016/j.survophthal.2014.10.001. Epub 2014 Oct 16. Surv Ophthalmol. 2015. PMID: 25890622 Review.
Retinoic acid is known to improve cutaneous wound healing and, in recent years, its application in ophthalmology has been investigated. This review looks at the role of retinoic acid on the ocular surface. Retinoic acid can be produced sy …
Retinoic acid is known to improve cutaneous wound healing and, in recent years, its application in ophthalmology has been inve …
40,908 results
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