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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 5
1992 43
1993 101
1994 181
1995 217
1996 226
1997 244
1998 256
1999 216
2000 247
2001 282
2002 259
2003 268
2004 275
2005 290
2006 269
2007 260
2008 249
2009 237
2010 233
2011 222
2012 213
2013 281
2014 238
2015 227
2016 179
2017 172
2018 173
2019 193
2020 150
2021 15
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5,896 results
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Page 1
Retinoid X Receptor Antagonists.
Watanabe M, Kakuta H. Watanabe M, et al. Int J Mol Sci. 2018 Aug 10;19(8):2354. doi: 10.3390/ijms19082354. Int J Mol Sci. 2018. PMID: 30103423 Free PMC article. Review.
Retinoid X receptor (RXR) antagonists are not only useful as chemical tools for biological research, but are also candidate drugs for the treatment of various diseases, including diabetes and allergies, although no RXR antagonist has yet been approved for cli
Retinoid X receptor (RXR) antagonists are not only useful as chemical tools for biological research, but are also candi
Retinoid X Receptor Selective Agonists and their Synthetic Methods.
Wagner CE, Jurutka PW, Marshall PA, Heck MC. Wagner CE, et al. Curr Top Med Chem. 2017;17(6):742-767. doi: 10.2174/1568026616666160617091559. Curr Top Med Chem. 2017. PMID: 27320333 Review.
Since the isolation and identification of the retinoid X receptor (RXR) as a member of the nuclear receptor (NR) superfamily in 1990, its analysis has ushered in a new understanding of physiological regulation by nuclear receptors, and novel met …
Since the isolation and identification of the retinoid X receptor (RXR) as a member of the nuclear receptor (NR) …
Alternative retinoid X receptor (RXR) ligands.
Krężel W, Rühl R, de Lera AR. Krężel W, et al. Mol Cell Endocrinol. 2019 Jul 1;491:110436. doi: 10.1016/j.mce.2019.04.016. Epub 2019 Apr 23. Mol Cell Endocrinol. 2019. PMID: 31026478 Review.
Retinoid X receptors (RXRs) control a wide variety of functions by virtue of their dimerization with other nuclear hormone receptors (NRs), contributing thereby to activities of different signaling pathways. ...
Retinoid X receptors (RXRs) control a wide variety of functions by virtue of their dimerization with other nuclear horm
Retinoid X receptor modulates olfactory attraction through Galpha signaling in the migratory locusts.
Ma Z, Liu J. Ma Z, et al. Insect Biochem Mol Biol. 2020 Jan;116:103265. doi: 10.1016/j.ibmb.2019.103265. Epub 2019 Nov 6. Insect Biochem Mol Biol. 2020. PMID: 31704156
The expression levels of retinaldehyde hydroxylase 1 (raldh1) and retinoid X receptor (rxr), which are two crucial genes for RA synthesis and signaling, were upregulated during 4 h of crowding. ...This study showed that RXR signaling mediates attraction by Ga …
The expression levels of retinaldehyde hydroxylase 1 (raldh1) and retinoid X receptor (rxr), which are two crucial gene …
Retinoid X receptor mediates brain clean-up after stroke.
Wood H. Wood H. Nat Rev Neurol. 2020 Mar;16(3):128-129. doi: 10.1038/s41582-020-0315-9. Nat Rev Neurol. 2020. PMID: 31988486 No abstract available.
A retinoid X receptor partial agonist attenuates pulmonary emphysema and airway inflammation.
Morichika D, Miyahara N, Fujii U, Taniguchi A, Oda N, Senoo S, Kataoka M, Tanimoto M, Kakuta H, Kiura K, Maeda Y, Kanehiro A. Morichika D, et al. Respir Res. 2019 Jan 3;20(1):2. doi: 10.1186/s12931-018-0963-0. Respir Res. 2019. PMID: 30606200 Free PMC article.
BACKGROUND: Retinoid X receptors (RXRs) are members of the nuclear receptor (NR) superfamily that mediate signalling by 9-cis retinoic acid, a vitamin A derivative. RXRs play key roles not only as homodimers but also as heterodimeric partners, e.g., fo …
BACKGROUND: Retinoid X receptors (RXRs) are members of the nuclear receptor (NR) superfamily that mediate signal …
Retinoid X Receptor Ligands with Anti-Type 2 Diabetic Activity.
Morishita KI, Kakuta H. Morishita KI, et al. Curr Top Med Chem. 2017;17(6):696-707. doi: 10.2174/1568026616666160617085545. Curr Top Med Chem. 2017. PMID: 27320332 Review.
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a ligand-dependent transcription factor that plays an important role in regulating glucose metabolism. ...However, the functional activity of PPARgamma is manifested by heterodimers of PPARgamma with retino
Peroxisome proliferator-activated receptor gamma (PPARgamma) is a ligand-dependent transcription factor that plays an important role …
Liver X Receptor/Retinoid X Receptor Pathway Plays a Regulatory Role in Pacing-Induced Cardiomyopathy.
Lin YS, Chang TH, Shi CS, Wang YZ, Ho WC, Huang HD, Chang ST, Pan KL, Chen MC. Lin YS, et al. J Am Heart Assoc. 2019 Jan 8;8(1):e009146. doi: 10.1161/JAHA.118.009146. J Am Heart Assoc. 2019. PMID: 30612502 Free PMC article.
Enrichment analysis using Ingenuity Pathway Analysis and the activation z-score analysis method demonstrated that there were 5 DEG s ( ABCA 1, APOD , CLU , LY 96, and SERPINF 1) in the LV septum (z-score=-0.447) and 5 DEG s ( APOD , CLU , LY 96, MSR 1, and SERPINF 1) in the LV fr …
Enrichment analysis using Ingenuity Pathway Analysis and the activation z-score analysis method demonstrated that there were 5 DEG s ( ABCA …
Retinoid X receptor ligands: a patent review (2007 - 2013).
Yamada S, Kakuta H. Yamada S, et al. Expert Opin Ther Pat. 2014 Apr;24(4):443-52. doi: 10.1517/13543776.2014.880692. Epub 2014 Jan 24. Expert Opin Ther Pat. 2014. PMID: 24456080 Review.
INTRODUCTION: Retinoid X receptors (RXRs) are nuclear receptors that act as ligand-dependent transcription factors. RXRs function as homodimers or as heterodimers with other nuclear receptors, such as retinoic acid receptors, PPARs, liver …
INTRODUCTION: Retinoid X receptors (RXRs) are nuclear receptors that act as ligand-dependent transcription facto …
A novel retinoid X receptor agonist, UAB30, inhibits rhabdomyosarcoma cells in vitro.
Williams AP, Waters AM, Stewart JE, Atigadda VR, Mroczek-Musulman E, Muccio DD, Grubbs CJ, Beierle EA. Williams AP, et al. J Surg Res. 2018 Aug;228:54-62. doi: 10.1016/j.jss.2018.02.057. Epub 2018 Mar 26. J Surg Res. 2018. PMID: 29907230 Free PMC article.
Rexinoids provide an alternative treatment approach to retinoic acid. Rexinoids primarily bind the retinoid X receptor with minimal retinoic acid receptor binding, the entity responsible for many of the toxicities of retinoid therapies. ...CONCL …
Rexinoids provide an alternative treatment approach to retinoic acid. Rexinoids primarily bind the retinoid X receptor
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