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2000 1
2001 3
2002 3
2003 4
2004 6
2005 2
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2007 5
2008 4
2009 5
2010 4
2011 1
2012 6
2013 5
2014 4
2015 2
2016 7
2017 3
2018 4
2019 3
2020 1
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Page 1
A partial agonist for retinoid X receptor mitigates experimental colitis.
Onuki M, Watanabe M, Ishihara N, Suzuki K, Takizawa K, Hirota M, Yamada T, Egawa A, Shibahara O, Nishii M, Fujihara M, Makishima M, Takahashi D, Furusawa Y, Kakuta H, Hase K. Onuki M, et al. Int Immunol. 2019 Mar 28;31(4):251-262. doi: 10.1093/intimm/dxy089. Int Immunol. 2019. PMID: 30590577
For example, animal fat-rich diets are predisposing factors for ulcerative colitis, whereas n-3 unsaturated fatty acids such as docosahexaenoic acid (DHA) show protective effects in experimental colitis and are negatively correlated with the incidence of ulce …
For example, animal fat-rich diets are predisposing factors for ulcerative colitis, whereas n-3 unsaturated fatty acids such as do
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Wang M, Ma LJ, Yang Y, Xiao Z, Wan JB. Wang M, et al. Crit Rev Food Sci Nutr. 2019;59(sup1):S116-S129. doi: 10.1080/10408398.2018.1544542. Epub 2018 Dec 22. Crit Rev Food Sci Nutr. 2019. PMID: 30580553 Review.
In the past decade, increasing attention has been paid to understand the association between n-3 polyunsaturated fatty acids (n-3 PUFAs) and ALD. ...ABBREVIATION AA arachidonic acid ACC acetyl-CoA carboxylase ACLY ATP-citrate lyase ACO acyl-CoA oxidase ALA α-linolen …
In the past decade, increasing attention has been paid to understand the association between n-3 polyunsaturated fatty acids (n-3 PUF …
Docosahexaenoic acid reduces haloperidol-induced dyskinesias in mice: involvement of Nur77 and retinoid receptors.
Ethier I, Kagechika H, Shudo K, Rouillard C, Lévesque D. Ethier I, et al. Biol Psychiatry. 2004 Oct 1;56(7):522-6. doi: 10.1016/j.biopsych.2004.06.036. Biol Psychiatry. 2004. PMID: 15450789
RESULTS: Nur77 gene ablation (knockout) or administration of a retinoid antagonist induced vacuous chewing movements and exacerbated those induced by haloperidol, whereas the retinoid agonist docosahexaenoic acid (an omega-3 polyunsaturated fatty ac
RESULTS: Nur77 gene ablation (knockout) or administration of a retinoid antagonist induced vacuous chewing movements and exacerbated …
Transcriptional and posttranscriptional repression of histone deacetylases by docosahexaenoic acid in macrophages.
Pham TX, Bae M, Lee Y, Park YK, Lee JY. Pham TX, et al. J Nutr Biochem. 2018 Jul;57:162-169. doi: 10.1016/j.jnutbio.2018.03.002. Epub 2018 Mar 10. J Nutr Biochem. 2018. PMID: 29734115
We determined the effects of fatty acids, including palmitic acid (PA), oleic acid (OA), linoleic acid, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on the expression of HDAC isoforms in RAW 264.7 macrophages, mouse …
We determined the effects of fatty acids, including palmitic acid (PA), oleic acid (OA), linoleic acid, eicosape …
Retinoid x receptor gamma is implicated in docosahexaenoic acid modulation of despair behaviors and working memory in mice.
Wietrzych-Schindler M, Szyszka-Niagolov M, Ohta K, Endo Y, Pérez E, de Lera AR, Chambon P, Krezel W. Wietrzych-Schindler M, et al. Biol Psychiatry. 2011 Apr 15;69(8):788-94. doi: 10.1016/j.biopsych.2010.12.017. Epub 2011 Feb 21. Biol Psychiatry. 2011. PMID: 21334601
BACKGROUND: Omega-3 polyunsaturated fatty acids, including docosahexaenoic acid (DHA), have antidepressant and promnemonic functions. The mechanisms of such activities are still elusive and may involve retinoid X receptors (RXRs), transcr …
BACKGROUND: Omega-3 polyunsaturated fatty acids, including docosahexaenoic acid (DHA), have antidepressant and promnemo …
Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the influence of LCPUFA on neural development, aging, and neurodegeneration.
Janssen CI, Kiliaan AJ. Janssen CI, et al. Prog Lipid Res. 2014 Jan;53:1-17. doi: 10.1016/j.plipres.2013.10.002. Epub 2013 Oct 24. Prog Lipid Res. 2014. PMID: 24334113 Review.
Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated fatty acids (LCPUFA) in neural development and neurodegeneration. ...The LCPUFA docosahexaenoic acid and arachidonic acid are important components of neuronal mem …
Many clinical and animal studies demonstrate the importance of long-chain polyunsaturated fatty acids (LCPUFA) in neural development …
Retinoid X receptor activation is essential for docosahexaenoic acid protection of retina photoreceptors.
German OL, Monaco S, Agnolazza DL, Rotstein NP, Politi LE. German OL, et al. J Lipid Res. 2013 Aug;54(8):2236-46. doi: 10.1194/jlr.M039040. Epub 2013 May 30. J Lipid Res. 2013. PMID: 23723389 Free PMC article.
We have established that docosahexaenoic acid (DHA), the major polyunsaturated fatty acid in the retina, promotes survival of rat retina photoreceptors during early development in vitro and upon oxidative stress by activating the ERK/MAPK signaling pathway. H …
We have established that docosahexaenoic acid (DHA), the major polyunsaturated fatty acid in the retina, promotes survi …
The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina.
SanGiovanni JP, Chew EY. SanGiovanni JP, et al. Prog Retin Eye Res. 2005 Jan;24(1):87-138. doi: 10.1016/j.preteyeres.2004.06.002. Prog Retin Eye Res. 2005. PMID: 15555528 Review.
Docosahexaenoic acid (DHA), a major dietary omega-3 LCPUFA, is also a major structural lipid of retinal photoreceptor outer segment membranes. ...DHA activates a number of nuclear hormone receptors that operate as transcription factors for molecules that modu
Docosahexaenoic acid (DHA), a major dietary omega-3 LCPUFA, is also a major structural lipid of retinal photoreceptor outer se
Postprandial lipoproteins and the molecular regulation of vascular homeostasis.
Botham KM, Wheeler-Jones CP. Botham KM, et al. Prog Lipid Res. 2013 Oct;52(4):446-64. doi: 10.1016/j.plipres.2013.06.001. Epub 2013 Jun 15. Prog Lipid Res. 2013. PMID: 23774609 Review.
Multiple receptor and non-receptor mediated pathways function in macrophage uptake of TRL. TRL also induce expression of adhesion molecules, cyclooxygenase-2 and heme-oxygenase-1 in endothelial cells, and activate intracellular signaling pathways involving mitogen-a …
Multiple receptor and non-receptor mediated pathways function in macrophage uptake of TRL. TRL also induce expression of adhes …
Polyunsaturated fatty acids including docosahexaenoic and arachidonic acid bind to the retinoid X receptor alpha ligand-binding domain.
Lengqvist J, Mata De Urquiza A, Bergman AC, Willson TM, Sjövall J, Perlmann T, Griffiths WJ. Lengqvist J, et al. Mol Cell Proteomics. 2004 Jul;3(7):692-703. doi: 10.1074/mcp.M400003-MCP200. Epub 2004 Apr 8. Mol Cell Proteomics. 2004. PMID: 15073272 Free article.
The retinoid X receptor (RXR) belongs to a subfamily of NRs that bind vitamin A metabolites (i.e. retinoids), including 9-cis-retinoic acid (9-cis-RA). ...Taken together, these results show that RXR binds PUFAs in solution and that these compounds indu …
The retinoid X receptor (RXR) belongs to a subfamily of NRs that bind vitamin A metabolites (i.e. retinoids), including …
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