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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1996 2
1997 2
1998 2
1999 1
2000 2
2001 7
2002 2
2003 5
2004 7
2005 6
2006 8
2007 3
2008 5
2009 7
2010 4
2011 6
2012 7
2013 8
2014 4
2015 7
2016 6
2017 2
2018 8
2019 9
2020 4
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111 results
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Page 1
A partial agonist for retinoid X receptor mitigates experimental colitis.
Onuki M, Watanabe M, Ishihara N, Suzuki K, Takizawa K, Hirota M, Yamada T, Egawa A, Shibahara O, Nishii M, Fujihara M, Makishima M, Takahashi D, Furusawa Y, Kakuta H, Hase K. Onuki M, et al. Int Immunol. 2019 Mar 28;31(4):251-262. doi: 10.1093/intimm/dxy089. Int Immunol. 2019. PMID: 30590577
Given that DHA exhibits agonistic activity on retinoid X receptor (RXR), activation of RXR could be a therapeutic strategy for IBD. ...Among many RXR-associated nuclear receptors, activation of peroxisome proliferator-activated receptor δ (PPARδ …
Given that DHA exhibits agonistic activity on retinoid X receptor (RXR), activation of RXR could be a therapeutic strat …
Retinoid X receptor-mediated neuroprotection via CYP19 upregulation and subsequent increases in estradiol synthesis.
Ishihara Y, Sakurai H, Oguro A, Tsuji M, Vogel CFA, Yamazaki T. Ishihara Y, et al. J Steroid Biochem Mol Biol. 2019 Oct;193:105421. doi: 10.1016/j.jsbmb.2019.105421. Epub 2019 Jun 29. J Steroid Biochem Mol Biol. 2019. PMID: 31265900
In this study, we investigated the effects of a potent retinoid X receptor (RXR) agonist, bexarotene, on estrogen synthesis and neuroprotective action in hippocampal slices. ...Bexarotene also suppressed neuronal injury induced by lipopolysaccharide in …
In this study, we investigated the effects of a potent retinoid X receptor (RXR) agonist, bexarotene, on estrogen synth …
Lipopolysaccharide downregulates the expressions of intestinal pregnane X receptor and cytochrome P450 3a11.
Xu DX, Wang JP, Sun MF, Chen YH, Wei W. Xu DX, et al. Eur J Pharmacol. 2006 Apr 24;536(1-2):162-70. doi: 10.1016/j.ejphar.2006.02.029. Epub 2006 Feb 28. Eur J Pharmacol. 2006. PMID: 16556443
The pregnane X receptor is a member of the nuclear receptor superfamily, which heterodimerize with the retinoid X receptor, and is an important regulator of cytochrome P450 3A (CYP3A). Lipopolysaccharide (LPS)-induced downregulatio …
The pregnane X receptor is a member of the nuclear receptor superfamily, which heterodimerize with the retinoid
Relationship between CYP3A29 and pregnane X receptor in landrace pigs: Pig CYP3A29 has a similar mechanism of regulation to human CYP3A4.
He Y, Zhou X, Li X, Jin X, Wang X, Pan X, Bi D. He Y, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2018 Dec;214:9-16. doi: 10.1016/j.cbpc.2018.08.006. Epub 2018 Aug 25. Comp Biochem Physiol C Toxicol Pharmacol. 2018. PMID: 30153482
Our results showed that CYP3A and metabolic nuclear receptor mRNAs were most highly expressed in liver tissues. The expression of the metabolic nuclear receptor pregnane X receptor (PXR) had a significant correlation with expression of CYP3A29, an anal …
Our results showed that CYP3A and metabolic nuclear receptor mRNAs were most highly expressed in liver tissues. The expression of the …
n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review.
Wang M, Ma LJ, Yang Y, Xiao Z, Wan JB. Wang M, et al. Crit Rev Food Sci Nutr. 2019;59(sup1):S116-S129. doi: 10.1080/10408398.2018.1544542. Epub 2018 Dec 22. Crit Rev Food Sci Nutr. 2019. PMID: 30580553 Review.
ABBREVIATION AA arachidonic acid ACC acetyl-CoA carboxylase ACLY ATP-citrate lyase ACO acyl-CoA oxidase ALA α-linolenic acid ALD alcoholic liver disease ALP alkaline phosphatase ALT alanine aminotransferase AMPK AMP-activated protein kinase AST aspartate aminotransferase ATGL adi …
ABBREVIATION AA arachidonic acid ACC acetyl-CoA carboxylase ACLY ATP-citrate lyase ACO acyl-CoA oxidase ALA α-linolenic acid ALD alcoholic l …
Retinoid X receptor beta polymorphisms do not explain functional differences in vitamins D and A response in Antineutrophil cytoplasmic antibody associated vasculitis patients.
Kälsch AI, Peters A, Buhl B, Breedijk A, Prem K, Schmitt WH, Weiss C, Heeringa P, Kallenberg C, Birck R, Yard BA. Kälsch AI, et al. Autoimmunity. 2009 Aug;42(5):467-74. doi: 10.1080/08916930902960347. Autoimmunity. 2009. PMID: 19811264 Clinical Trial.
It has been suggested that the retinoid X receptor beta (RXRB) gene is a risk factor for Wegener's granulomatosis. We addressed if there is a functional difference in the response to retinoic acid (RA) and vitamin D in Antineutrophil cytoplasmic antibody (ANC …
It has been suggested that the retinoid X receptor beta (RXRB) gene is a risk factor for Wegener's granulomatosis. We a …
Emerging role of microRNAs in lipid metabolism.
Yang Z, Cappello T, Wang L. Yang Z, et al. Acta Pharm Sin B. 2015 Mar;5(2):145-50. doi: 10.1016/j.apsb.2015.01.002. Epub 2015 Feb 24. Acta Pharm Sin B. 2015. PMID: 26579440 Free PMC article. Review.
Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines.
Wang Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. Wang Y, et al. J Lipid Res. 2005 Nov;46(11):2377-87. doi: 10.1194/jlr.M500134-JLR200. Epub 2005 Aug 16. J Lipid Res. 2005. PMID: 16106051 Free article.
Therefore, we examined the expression of liver X receptor/retinoid X receptor (LXR/RXR) and their target genes in kidney from mice treated with lipopolysaccharide (LPS) and in human proximal tubular HK-2 cells treated with interleukin-1be …
Therefore, we examined the expression of liver X receptor/retinoid X receptor (LXR/RXR) and their target …
Postprandial lipoproteins and the molecular regulation of vascular homeostasis.
Botham KM, Wheeler-Jones CP. Botham KM, et al. Prog Lipid Res. 2013 Oct;52(4):446-64. doi: 10.1016/j.plipres.2013.06.001. Epub 2013 Jun 15. Prog Lipid Res. 2013. PMID: 23774609 Review.
Multiple receptor and non-receptor mediated pathways function in macrophage uptake of TRL. TRL also induce expression of adhesion molecules, cyclooxygenase-2 and heme-oxygenase-1 in endothelial cells, and activate intracellular signaling pathways involving mitogen-a …
Multiple receptor and non-receptor mediated pathways function in macrophage uptake of TRL. TRL also induce expression of adhes …
Retinoid receptor expression and its correlation to retinoid sensitivity in non-M3 acute myeloid leukemia blast cells.
Lehmann S, Paul C, Törmä H. Lehmann S, et al. Clin Cancer Res. 2001 Feb;7(2):367-73. Clin Cancer Res. 2001. PMID: 11234892 Free article.
Retinoids exert their effects through a number of nuclear receptors [retinoic acid receptors (RARs) and retinoid X receptors (RXRs)]. ...There was no correlation between the basal expression of any of the retinoid receptors and sen …
Retinoids exert their effects through a number of nuclear receptors [retinoic acid receptors (RARs) and retinoid X
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