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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1994 1
1995 1
1999 1
2000 1
2001 2
2004 1
2005 2
2006 5
2007 2
2008 3
2009 4
2010 4
2011 5
2012 5
2013 3
2014 4
2015 7
2016 9
2017 8
2018 8
2019 11
2020 6
2021 10
2022 18
2023 13
2024 1

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127 results

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Page 1
Retinoid X receptor gamma dictates the activation threshold of group 2 innate lymphoid cells and limits type 2 inflammation in the small intestine.
Zang Y, Liu S, Rao Z, Wang Y, Zhang B, Li H, Cao Y, Zhou J, Shen Z, Duan S, He D, Xu H. Zang Y, et al. Immunity. 2023 Nov 14;56(11):2542-2554.e7. doi: 10.1016/j.immuni.2023.08.019. Epub 2023 Sep 14. Immunity. 2023. PMID: 37714152
However, the molecular checkpoints in ILC2s that determine whether to immediately launch a proinflammatory response are unknown. Here, we found that retinoid X receptor gamma (Rxrg) was highly expressed in small intestinal ILC2s and rapidly supp …
However, the molecular checkpoints in ILC2s that determine whether to immediately launch a proinflammatory response are unknown. Here, we fo …
Toward Minimal Residual Disease-Directed Therapy in Melanoma.
Rambow F, Rogiers A, Marin-Bejar O, Aibar S, Femel J, Dewaele M, Karras P, Brown D, Chang YH, Debiec-Rychter M, Adriaens C, Radaelli E, Wolter P, Bechter O, Dummer R, Levesque M, Piris A, Frederick DT, Boland G, Flaherty KT, van den Oord J, Voet T, Aerts S, Lund AW, Marine JC. Rambow F, et al. Cell. 2018 Aug 9;174(4):843-855.e19. doi: 10.1016/j.cell.2018.06.025. Epub 2018 Jul 12. Cell. 2018. PMID: 30017245 Free article.
One of these exhibited a neural crest stem cell (NCSC) transcriptional program largely driven by the nuclear receptor RXRG. An RXR antagonist mitigated accumulation of NCSCs in MRD and delayed the development of resistance. ...
One of these exhibited a neural crest stem cell (NCSC) transcriptional program largely driven by the nuclear receptor RXRG. An RXR an …
Retinoid X receptor gamma (RXRG) is an independent prognostic biomarker in ER-positive invasive breast cancer.
Joseph C, Al-Izzi S, Alsaleem M, Kurozumi S, Toss MS, Arshad M, Goh FQ, Alshankyty IM, Aleskandarany MA, Ali S, Ellis IO, Mongan NP, Green AR, Rakha EA. Joseph C, et al. Br J Cancer. 2019 Oct;121(9):776-785. doi: 10.1038/s41416-019-0589-0. Epub 2019 Sep 27. Br J Cancer. 2019. PMID: 31558802 Free PMC article.
BACKGROUND: Retinoid X Receptor Gamma (RXRG) is a member of the nuclear receptor superfamily and plays a role in tumour suppression. ...ER signalling pathway was the top predicted master regulator of RXRG protein expression (p = 0.005). C …
BACKGROUND: Retinoid X Receptor Gamma (RXRG) is a member of the nuclear receptor superfamily and plays a …
Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury.
Zhang X, Gong P, Zhao Y, Wan T, Yuan K, Xiong Y, Wu M, Zha M, Li Y, Jiang T, Liu X, Ye R, Xie Y, Xu G. Zhang X, et al. EBioMedicine. 2022 Oct;84:104275. doi: 10.1016/j.ebiom.2022.104275. Epub 2022 Sep 21. EBioMedicine. 2022. PMID: 36152520 Free PMC article.
Specific enhanced expression of endothelial Cav-1 by AAV-Tie1-Cav-1 remarkably reduced infarct volume, attenuated vascular hyper-permeability and alleviated thrombo-inflammation in both wild-type and Cav-1(-/-) tMCAO mice. Transcriptome analysis after tMCAO further designated …
Specific enhanced expression of endothelial Cav-1 by AAV-Tie1-Cav-1 remarkably reduced infarct volume, attenuated vascular hyper-permeabilit …
Regulation of prefrontal patterning and connectivity by retinoic acid.
Shibata M, Pattabiraman K, Lorente-Galdos B, Andrijevic D, Kim SK, Kaur N, Muchnik SK, Xing X, Santpere G, Sousa AMM, Sestan N. Shibata M, et al. Nature. 2021 Oct;598(7881):483-488. doi: 10.1038/s41586-021-03953-x. Epub 2021 Oct 1. Nature. 2021. PMID: 34599305 Free PMC article.
Genetic deletions in mice revealed that retinoic acid signalling through the retinoic acid receptors RXRG and RARB, as well as CYP26B1-dependent catabolism, are involved in proper molecular patterning of prefrontal and motor areas, development of PFC-mediodorsal thalamus c …
Genetic deletions in mice revealed that retinoic acid signalling through the retinoic acid receptors RXRG and RARB, as well as CYP26B …
Direct neuronal reprogramming by temporal identity factors.
Boudreau-Pinsonneault C, David LA, Lourenço Fernandes JA, Javed A, Fries M, Mattar P, Cayouette M. Boudreau-Pinsonneault C, et al. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2122168120. doi: 10.1073/pnas.2122168120. Epub 2023 May 1. Proc Natl Acad Sci U S A. 2023. PMID: 37126716 Free PMC article.
Using genetic lineage tracing, histological, immunohistochemical, and single-cell transcriptome and multiome analyses, we show that expression of Ikzf1/4 in MG in vivo, without retinal injury, mostly generates iONL cells that share molecular characteristics with bipolar cells, al …
Using genetic lineage tracing, histological, immunohistochemical, and single-cell transcriptome and multiome analyses, we show that expressi …
Expression and localization of retinoid receptors in the testis of normal and infertile men.
Wang GS, Liang A, Dai YB, Wu XL, Sun F. Wang GS, et al. Mol Reprod Dev. 2020 Sep;87(9):978-985. doi: 10.1002/mrd.23412. Epub 2020 Aug 7. Mol Reprod Dev. 2020. PMID: 32770619
RA activates downstream pathways through its receptors (retinoic acid receptor alpha [RARA], retinoic acid receptor beta, and retinoic acid receptor gamma [RARG]) and retinoid X receptors (retinoid X receptor alpha [RXRA], retinoid X receptor beta [RXRB], and retinoid X …
RA activates downstream pathways through its receptors (retinoic acid receptor alpha [RARA], retinoic acid receptor beta, and retinoic acid …
Association Between Retinoid X Receptor Gene Variants and Dyslipidemia Risk in an Iranian Population.
Vafaeie F, Kazemi T, Khosravi S, Miri Moghaddam E. Vafaeie F, et al. Cureus. 2021 Sep 5;13(9):e17730. doi: 10.7759/cureus.17730. eCollection 2021 Sep. Cureus. 2021. PMID: 34659944 Free PMC article.
Methods To study the possible role of the RXR genes in genetic susceptibility of dyslipidemia, three selected polymorphisms, rs3132294 located in RXRA (RXR-alpha) gene and rs2651860 and rs1128977 located in RXRG (RXR-gamma) gene, were investigated in 391 individuals with t …
Methods To study the possible role of the RXR genes in genetic susceptibility of dyslipidemia, three selected polymorphisms, rs3132294 locat …
A framework to identify functional interactors that contribute to disrupted early retinal development in Vsx2 ocular retardation J mice.
Leung AM, Rao MB, Raju N, Chung M, Klinger A, Rowe DJ, Li X, Levine EM. Leung AM, et al. Dev Dyn. 2023 Nov;252(11):1338-1362. doi: 10.1002/dvdy.629. Epub 2023 Jun 1. Dev Dyn. 2023. PMID: 37259952 Free PMC article.
This was first tested in vivo with Mitf, a target of Vsx2 repression, and then to cultures of orJ retina treated with inhibitors of Retinoid-X Receptors (RXR) to target Rxrg, an up-regulated gene in the orJ retina, and gamma-Secretase, an enzyme required for Notch signalin …
This was first tested in vivo with Mitf, a target of Vsx2 repression, and then to cultures of orJ retina treated with inhibitors of Retinoid …
127 results