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1985 1
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2002 4
2003 2
2004 1
2005 2
2007 1
2008 6
2009 3
2010 5
2011 6
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2014 1
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2017 6
2019 4
2020 5
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The natural history of primary sclerosing cholangitis in 781 children: A multicenter, international collaboration.
Deneau MR, El-Matary W, Valentino PL, Abdou R, Alqoaer K, Amin M, Amir AZ, Auth M, Bazerbachi F, Broderick A, Chan A, Cotter J, Doan S, El-Youssef M, Ferrari F, Furuya KN, Gottrand M, Gottrand F, Gupta N, Homan M, Kamath BM, Kim KM, Kolho KL, Konidari A, Koot B, Iorio R, Ledder O, Mack C, Martinez M, Miloh T, Mohan P, O'Cathain N, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Vos MB, Woynarowski M, Yap J, Jensen MK. Deneau MR, et al. Hepatology. 2017 Aug;66(2):518-527. doi: 10.1002/hep.29204. Epub 2017 Jun 26. Hepatology. 2017. PMID: 28390159
We identified 781 patients, median age 12 years, with 4,277 person-years of follow-up; 33% with autoimmune hepatitis, 76% with inflammatory bowel disease, and 13% with small duct PSC. ...In multivariate analysis PSC-inflammatory bowel disease and sm
We identified 781 patients, median age 12 years, with 4,277 person-years of follow-up; 33% with autoimmune hepatitis, 76% with inflammatory …
Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis.
Weismüller TJ, Trivedi PJ, Bergquist A, Imam M, Lenzen H, Ponsioen CY, Holm K, Gotthardt D, Färkkilä MA, Marschall HU, Thorburn D, Weersma RK, Fevery J, Mueller T, Chazouillères O, Schulze K, Lazaridis KN, Almer S, Pereira SP, Levy C, Mason A, Naess S, Bowlus CL, Floreani A, Halilbasic E, Yimam KK, Milkiewicz P, Beuers U, Huynh DK, Pares A, Manser CN, Dalekos GN, Eksteen B, Invernizzi P, Berg CP, Kirchner GI, Sarrazin C, Zimmer V, Fabris L, Braun F, Marzioni M, Juran BD, Said K, Rupp C, Jokelainen K, Benito de Valle M, Saffioti F, Cheung A, Trauner M, Schramm C, Chapman RW, Karlsen TH, Schrumpf E, Strassburg CP, Manns MP, Lindor KD, Hirschfield GM, Hansen BE, Boberg KM; International PSC Study Group. Weismüller TJ, et al. Gastroenterology. 2017 Jun;152(8):1975-1984.e8. doi: 10.1053/j.gastro.2017.02.038. Epub 2017 Mar 6. Gastroenterology. 2017. PMID: 28274849 Free PMC article.
Small-duct PSC was associated with a lower risk of LTD or malignancy compared with classic PSC (HR, 0.30 and HR, 0.15, respectively; both P < .001). ...In multivariable analyses assessing the primary endpoint, small-duct PSC cha
Small-duct PSC was associated with a lower risk of LTD or malignancy compared with classic PSC (HR, 0.30 and HR,
Pathogenesis and clinical spectrum of primary sclerosing cholangitis.
Gidwaney NG, Pawa S, Das KM. Gidwaney NG, et al. World J Gastroenterol. 2017 Apr 14;23(14):2459-2469. doi: 10.3748/wjg.v23.i14.2459. World J Gastroenterol. 2017. PMID: 28465630 Free PMC article. Review.
Small-duct PSC, a variant of PSC, also has an association with inflammatory bowel disease. The exact pathogenesis of PSC is not well understood at present, however, is likely a combination of a genetic predisposition with alteration of the molec
Small-duct PSC, a variant of PSC, also has an association with inflammatory bowel disease. The exact pathogenesi
Clinical Characteristics, Associated Malignancies and Management of Primary Sclerosing Cholangitis in Inflammatory Bowel Disease Patients: A Multicentre Retrospective Cohort Study.
Guerra I, Bujanda L, Castro J, Merino O, Tosca J, Camps B, Gutiérrez A, Gordillo Ábalos J, de Castro L, Iborra M, Carbajo AY, Taxonera C, Rodríguez-Lago I, Mesonero F, de Francisco R, Gómez-Gómez GJ, Chaparro M, Tardillo CA, Rivero M, Algaba A, Martín Arranz E, Cañete F, Vicente R, Sicilia B, Antolín B, Prieto V, Márquez L, Benítez JM, Camo P, Piqueras M, Gargallo CJ, Hinojosa E, Huguet JM, Pérez Calle JL, Van Domselaar M, Rodriguez C, Calvet X, Muñoz-Villafranca C, García-Sepulcre MF, Munoz-Garrido P, Fernández-Clotet A, Gómez Irwin L, Hernández S, Guardiola J, Sempere L, González Muñoza C, Hernández V, Beltrán B, Barrio J, Alba C, Moraleja I, López-Sanromán A, Riestra S, Martínez Montiel P, Garre A, Arranz L, García MJ, Martín Arranz MD, Corsino P, Arias L, Fernández-Salazar L, Fernández-Pordomingo A, Andreu M, Iglesias E, Ber Y, Mena R, Arroyo Villarino MT, Mora M, Ruiz L, López-Serrano P, Blazquez I, Villoria A, Fernández M, Bermejo F, Banales JM, Domènech E, Gisbert JP; Spanish GETECCU group (ENEIDA Project). Guerra I, et al. J Crohns Colitis. 2019 Dec 10;13(12):1492-1500. doi: 10.1093/ecco-jcc/jjz094. J Crohns Colitis. 2019. PMID: 31063540
It was more common in intra- and extrahepatic PSC compared with small-duct PSC (16.3% vs 3.3%; odds ratio [OR] 5.7: 95% confidence interval [CI] = 1.7-19.3). ...CONCLUSIONS: PSC-IBD patients with symptoms of PSC at PSC diagnosis ha …
It was more common in intra- and extrahepatic PSC compared with small-duct PSC (16.3% vs 3.3%; odds ratio [OR] 5 …
Small-duct primary sclerosing cholangitis.
Björnsson E. Björnsson E. Curr Gastroenterol Rep. 2009 Feb;11(1):37-41. doi: 10.1007/s11894-009-0006-6. Curr Gastroenterol Rep. 2009. PMID: 19166657
Three papers published in 2002 on small-duct PSC patients suggested a better prognosis in patients with small-duct PSC than in those with large-duct PSC. ...Recurrence of small-duct PSC after liver trans …
Three papers published in 2002 on small-duct PSC patients suggested a better prognosis in patients with small- …
Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease.
Naess S, Björnsson E, Anmarkrud JA, Al Mamari S, Juran BD, Lazaridis KN, Chapman R, Bergquist A, Melum E, Marsh SG, Schrumpf E, Lie BA, Boberg KM, Karlsen TH, Hov JR. Naess S, et al. Liver Int. 2014 Nov;34(10):1488-95. doi: 10.1111/liv.12492. Epub 2014 Mar 7. Liver Int. 2014. PMID: 24517468 Free PMC article.
In contrast, small duct PSC without IBD was only associated with HLA-DRB1*13:01(P = 0.03) and was otherwise distinctly dissimilar from large duct PSC. CONCLUSIONS: Small duct PSC with IBD resembles large duct PSC
In contrast, small duct PSC without IBD was only associated with HLA-DRB1*13:01(P = 0.03) and was otherwise distinctly …
The natural history of small-duct primary sclerosing cholangitis.
Björnsson E, Olsson R, Bergquist A, Lindgren S, Braden B, Chapman RW, Boberg KM, Angulo P. Björnsson E, et al. Gastroenterology. 2008 Apr;134(4):975-80. doi: 10.1053/j.gastro.2008.01.042. Epub 2008 Jan 17. Gastroenterology. 2008. PMID: 18395078
Two patients with small-duct PSC who underwent liver transplantation had recurrence of small-duct PSC in the graft 9 and 13 years, respectively, after transplantation. ...Small-duct PSC may recur after liver transplan …
Two patients with small-duct PSC who underwent liver transplantation had recurrence of small-duct PSC
Small-duct primary sclerosing cholangitis.
Ludwig J. Ludwig J. Semin Liver Dis. 1991 Feb;11(1):11-7. doi: 10.1055/s-2008-1040417. Semin Liver Dis. 1991. PMID: 2047885 Review.
If the affected bile ducts are too small for cholangiographic identification, the best designation for the condition is small-duct PSC; cholangiographically identifiable duct changes are the hallmark of large-duct PSC. The term " …
If the affected bile ducts are too small for cholangiographic identification, the best designation for the condition is small- …
Clinical profile and outcome of primary sclerosing cholangitis: A single-centre experience from western India.
Tibdewal P, Bhatt P, Jain A, Gupta D, Bhatia S, Shukla A. Tibdewal P, et al. Indian J Gastroenterol. 2019 Aug;38(4):295-302. doi: 10.1007/s12664-019-00968-1. Epub 2019 Sep 12. Indian J Gastroenterol. 2019. PMID: 31515764
RESULTS: We identified 28 (18 men) patients with PSC (19, 67% large-duct and 9, 33% small-duct) with a median age of 31.5 years (range 7-63 years) with median duration of follow up of 24 months (6-125 months). ...CONCLUSION: PSC commonly present …
RESULTS: We identified 28 (18 men) patients with PSC (19, 67% large-duct and 9, 33% small-duct) with a median ag …
Long-term outcomes of pediatric-onset primary sclerosing cholangitis: A single-center experience in Japan.
Umetsu S, Notohara K, Nakazawa T, Tsunoda T, Sogo T, Komatsu H, Tanaka A, Tazuma S, Takikawa H, Inui A, Fujisawa T. Umetsu S, et al. Hepatol Res. 2019 Dec;49(12):1386-1397. doi: 10.1111/hepr.13421. Epub 2019 Sep 11. Hepatol Res. 2019. PMID: 31408920
AIM: Primary sclerosing cholangitis (PSC) is very rare in Japan. Although a large-scale cohort study of 781 pediatric-onset PSC patients in Europe and North America showed that the 5-year survival with native liver was 88%, the long-term outcomes of pediatric-onset …
AIM: Primary sclerosing cholangitis (PSC) is very rare in Japan. Although a large-scale cohort study of 781 pediatric-onset PSC
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