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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1901 1
1904 2
1908 4
1909 2
1910 1
1911 5
1912 3
1913 6
1914 10
1915 6
1916 2
1917 2
1918 2
1921 2
1922 3
1923 1
1924 1
1925 5
1926 2
1927 3
1928 8
1929 5
1930 6
1931 3
1933 9
1934 4
1935 3
1936 4
1937 11
1938 5
1939 3
1940 3
1942 1
1943 1
1945 12
1946 26
1947 37
1948 41
1949 51
1950 87
1951 74
1952 84
1953 43
1954 88
1955 80
1956 63
1957 72
1958 65
1959 54
1960 50
1961 64
1962 93
1963 227
1964 277
1965 157
1966 147
1967 211
1968 271
1969 275
1970 253
1971 239
1972 277
1973 326
1974 300
1975 285
1976 213
1977 254
1978 223
1979 227
1980 214
1981 220
1982 231
1983 243
1984 261
1985 247
1986 239
1987 239
1988 246
1989 327
1990 331
1991 309
1992 313
1993 317
1994 307
1995 302
1996 343
1997 311
1998 301
1999 293
2000 330
2001 360
2002 388
2003 398
2004 392
2005 407
2006 399
2007 440
2008 453
2009 459
2010 468
2011 482
2012 579
2013 593
2014 670
2015 626
2016 648
2017 601
2018 597
2019 601
2020 532
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20,467 results
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Page 1
Splenomegaly: investigation, diagnosis and management.
Pozo AL, Godfrey EM, Bowles KM. Pozo AL, et al. Blood Rev. 2009 May;23(3):105-11. doi: 10.1016/j.blre.2008.10.001. Epub 2008 Dec 4. Blood Rev. 2009. PMID: 19062140 Review.
Splenomegaly is a feature of a broad range of diseases, and presents to clinicians in many fields. This review examines the aetiology of splenomegaly in the developed world, and describes a logical approach to the patient with splenomegaly. ...We discuss the
Splenomegaly is a feature of a broad range of diseases, and presents to clinicians in many fields. This review examines the aetiology
Splenomegaly: Pathophysiological bases and therapeutic options.
McKenzie CV, Colonne CK, Yeo JH, Fraser ST. McKenzie CV, et al. Int J Biochem Cell Biol. 2018 Jan;94:40-43. doi: 10.1016/j.biocel.2017.11.011. Epub 2017 Dec 2. Int J Biochem Cell Biol. 2018. PMID: 29191734 Review.
This remarkable property of the spleen to expand is termed splenomegaly. Splenomegaly can occur as a physiological response to stress or as a chronic process that is often detrimental to the wellbeing of the individual. ...Additionally we will address experimental s …
This remarkable property of the spleen to expand is termed splenomegaly. Splenomegaly can occur as a physiological response to …
Splenomegaly.
Brown NF, Marks DJ, Smith PJ, Bloom SL. Brown NF, et al. Br J Hosp Med (Lond). 2011 Nov;72(11):M166-9. doi: 10.12968/hmed.2011.72.sup11.m166. Br J Hosp Med (Lond). 2011. PMID: 22082977 Review.
Splenomegaly is a common finding on clinical examination, and frequently features in postgraduate assessments. The spleen does not normally descend below the left costal margin. The routine abdominal examination will identify whether the spleen is palpable, and if so sp
Splenomegaly is a common finding on clinical examination, and frequently features in postgraduate assessments. The spleen does not no
Splenomegaly - Diagnostic validity, work-up, and underlying causes.
Curovic Rotbain E, Lund Hansen D, Schaffalitzky de Muckadell O, Wibrand F, Meldgaard Lund A, Frederiksen H. Curovic Rotbain E, et al. PLoS One. 2017 Nov 14;12(11):e0186674. doi: 10.1371/journal.pone.0186674. eCollection 2017. PLoS One. 2017. PMID: 29135986 Free PMC article.
PURPOSE: Our aim was to assess the validity of the ICD-10 code for splenomegaly in the Danish National Registry of Patients (DNRP), as well as to investigate which underlying diseases explained the observed splenomegaly. ...None of the investigated patients with idi …
PURPOSE: Our aim was to assess the validity of the ICD-10 code for splenomegaly in the Danish National Registry of Patients (DNRP), a …
Idiopathic Portal Hypertension.
Hernández-Gea V, Baiges A, Turon F, Garcia-Pagán JC. Hernández-Gea V, et al. Hepatology. 2018 Dec;68(6):2413-2423. doi: 10.1002/hep.30132. Hepatology. 2018. PMID: 30066417 Review.
Laboratory tests often reveal a preserved liver function with anemia, leukopenia, and thrombocytopenia due to splenomegaly. Imaging studies reveal signs of portal hypertension, whereas liver stiffness and portal pressure values are usually normal or slightly elevated. ...
Laboratory tests often reveal a preserved liver function with anemia, leukopenia, and thrombocytopenia due to splenomegaly. Imaging s …
Splenomegaly: A Combined Clinical and Radiologic Approach to the Differential Diagnosis.
Sjoberg BP, Menias CO, Lubner MG, Mellnick VM, Pickhardt PJ. Sjoberg BP, et al. Gastroenterol Clin North Am. 2018 Sep;47(3):643-666. doi: 10.1016/j.gtc.2018.04.009. Epub 2018 Jul 7. Gastroenterol Clin North Am. 2018. PMID: 30115442 Review.
An enlarged spleen (splenomegaly) is a common imaging finding and may be related to a broad array of underlying conditions. The multifaceted functions of the spleen make it susceptible to involvement by a variety of pathophysiologic processes. ...
An enlarged spleen (splenomegaly) is a common imaging finding and may be related to a broad array of underlying conditions. The multi …
The hyper-reactive malarial splenomegaly: a systematic review of the literature.
Leoni S, Buonfrate D, Angheben A, Gobbi F, Bisoffi Z. Leoni S, et al. Malar J. 2015 Apr 29;14:185. doi: 10.1186/s12936-015-0694-3. Malar J. 2015. PMID: 25925423 Free PMC article. Review.
BACKGROUND: The hyper-reactive malarial splenomegaly syndrome (HMS) is a leading cause of massive splenomegaly in malaria-endemic countries. ...In different African countries, 31 to 76% of all splenomegalies were caused by HMS. Fatality rate reached 36% in th …
BACKGROUND: The hyper-reactive malarial splenomegaly syndrome (HMS) is a leading cause of massive splenomegaly in malaria-ende …
[Hepatosplenomegaly].
Hinrichsen H, Fölsch UR. Hinrichsen H, et al. Internist (Berl). 1994 May;35(5):501-13. Internist (Berl). 1994. PMID: 8021122 Review. German. No abstract available.
Indications and outcome of splenectomy in hematologic disease.
Bonnet S, Guédon A, Ribeil JA, Suarez F, Tamburini J, Gaujoux S. Bonnet S, et al. J Visc Surg. 2017 Dec;154(6):421-429. doi: 10.1016/j.jviscsurg.2017.06.011. Epub 2017 Jul 27. J Visc Surg. 2017. PMID: 28757383 Review.
Nonetheless, splenectomy has its place in hemoglobinopathies and hemolytic diseases, improves thrombocytopenia in refractory immune thrombocytopenic purpura, can reverse sequelae linked to voluminous splenomegaly secondary to myelofibrosis, or can be used for diagnostic pu …
Nonetheless, splenectomy has its place in hemoglobinopathies and hemolytic diseases, improves thrombocytopenia in refractory immune thromboc …
Multifactorial Splenomegaly.
Allison J, Sunne R, Huntington M. Allison J, et al. S D Med. 2017 Dec;70(12):535-538. S D Med. 2017. PMID: 29334440
Splenomegaly is an unusual finding among North Americans, but is commonly seen in many parts of the world. Increasingly, it can be encountered locally among recent immigrant and refugee populations. ...We report the case of a 33-year-old refugee with multiple potential cau
Splenomegaly is an unusual finding among North Americans, but is commonly seen in many parts of the world. Increasingly, it can be en
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