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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1951 1
1952 1
1960 1
1962 1
1964 1
1995 1
1996 1
1997 11
1998 22
1999 47
2000 75
2001 97
2002 105
2003 145
2004 172
2005 201
2006 256
2007 241
2008 283
2009 261
2010 263
2011 308
2012 324
2013 379
2014 359
2015 317
2016 321
2017 344
2018 298
2019 338
2020 178
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4,753 results
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Suppressor of cytokine signaling (SOCS) genes are downregulated in breast cancer.
Ghafouri-Fard S, Oskooei VK, Azari I, Taheri M. Ghafouri-Fard S, et al. World J Surg Oncol. 2018 Nov 19;16(1):226. doi: 10.1186/s12957-018-1529-9. World J Surg Oncol. 2018. PMID: 30453988 Free PMC article.
BACKGROUND: The suppressor of cytokine signaling (SOCS) family of proteins are inhibitors of the cytokine-activated Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway. ...
BACKGROUND: The suppressor of cytokine signaling (SOCS) family of proteins are inhibitors of the cytokine-activa …
Suppressors of cytokine signaling: Potential immune checkpoint molecules for cancer immunotherapy.
Chikuma S, Kanamori M, Mise-Omata S, Yoshimura A. Chikuma S, et al. Cancer Sci. 2017 Apr;108(4):574-580. doi: 10.1111/cas.13194. Epub 2017 Apr 19. Cancer Sci. 2017. PMID: 28188673 Free PMC article. Review.
The third T cell activation signal represents the signals from the cytokine receptors. The cytokine interferon-γ (IFNγ) plays an important role in anti-tumor immunity by activating cytotoxic T cells (CTLs). Most cytokines use the Janus kinase (JAK)/signal transducer …
The third T cell activation signal represents the signals from the cytokine receptors. The cytokine interferon-γ (IFNγ) plays …
Potential roles of suppressor of cytokine signaling in wound healing.
Feng Y, Sanders AJ, Morgan LD, Harding KG, Jiang WG. Feng Y, et al. Regen Med. 2016 Mar;11(2):193-209. doi: 10.2217/rme.16.4. Epub 2016 Feb 15. Regen Med. 2016. PMID: 26877242 Review.
This complex process is regulated by numerous cytokines, with dysregulation of cytokine-induced signaling leading to impaired wound healing. Suppressor of cytokine signaling (SOCS) proteins are a family of eight intracellular proteins which may …
This complex process is regulated by numerous cytokines, with dysregulation of cytokine-induced signaling leading to impaired …
Suppressor of cytokine signaling genes in renal transplant receivers: Association with transplant fate.
Nafar M, Kalantari S, Omrani MD, Samavat S, Arsang-Jang S, Taheri M, Ghafouri-Fard S. Nafar M, et al. Transpl Immunol. 2019 Oct;56:101228. doi: 10.1016/j.trim.2019.101228. Epub 2019 Aug 6. Transpl Immunol. 2019. PMID: 31398463
Suppressor of cytokine signaling (SOCS) proteins have acknowledged roles in regulation of immune responses. Moreover, their role in the evolution of allograft rejection is being elucidated. ...
Suppressor of cytokine signaling (SOCS) proteins have acknowledged roles in regulation of immune responses. Moreover, t
Suppressor of cytokine signaling and accelerated atherosclerosis in kidney disease.
Wesoly J, Sikorski K, Lee CK, Bluyssen HA. Wesoly J, et al. Acta Biochim Pol. 2010;57(3):251-60. Epub 2010 Aug 19. Acta Biochim Pol. 2010. PMID: 20725646 Free article. Review.
Thus, pathways capable of suppressing proinflammatory cytokine signaling hold the potential to limit life-threatening cardiovascular events caused by atherogenesis. Suppressor of cytokine signaling (SOCS) are a family of intracellular proteins, …
Thus, pathways capable of suppressing proinflammatory cytokine signaling hold the potential to limit life-threatening cardiova …
Suppressor of cytokine signaling in allergic inflammation.
Knisz J, Rothman PB. Knisz J, et al. J Allergy Clin Immunol. 2007 Mar;119(3):739-45. doi: 10.1016/j.jaci.2006.12.620. Epub 2007 Jan 25. J Allergy Clin Immunol. 2007. PMID: 17258308 Review.
The suppressor of cytokine signaling (SOCS) protein family represents a novel group of cytoplasmic negative feedback regulators of type I and II cytokines. Several of the signaling pathways regulated by SOCS proteins are important in allergic immune re …
The suppressor of cytokine signaling (SOCS) protein family represents a novel group of cytoplasmic negative feedback re …
Suppressor of cytokine signaling 3 (SOCS3) is related to pro-inflammatory cytokine production and triglyceride deposition in turbot (Scophthalmus maximus).
Tan P, Peng M, Liu D, Guo H, Mai K, Nian R, Macq B, Ai Q. Tan P, et al. Fish Shellfish Immunol. 2017 Nov;70:381-390. doi: 10.1016/j.fsi.2017.09.006. Epub 2017 Sep 4. Fish Shellfish Immunol. 2017. PMID: 28882805
Studies in mammals have indicated that a relationship exists between pro-inflammatory cytokine overexpression and altered lipid metabolism through the activation of suppressor of cytokine signaling 3 (SOCS3). ...These results suggest that the HLD and O …
Studies in mammals have indicated that a relationship exists between pro-inflammatory cytokine overexpression and altered lipid metab …
Suppressor of cytokine signaling proteins as regulators of innate immune signaling.
Strebovsky J, Walker P, Dalpke AH. Strebovsky J, et al. Front Biosci (Landmark Ed). 2012 Jan 1;17:1627-39. doi: 10.2741/4008. Front Biosci (Landmark Ed). 2012. PMID: 22201825 Review.
Suppressor of cytokine signaling (SOCS) proteins have been identified as crucial negative regulators of various hematopoietic cytokines employing Janus kinas (JAK) and signal transducer and activator of transcription (STAT) signaling. Further results n
Suppressor of cytokine signaling (SOCS) proteins have been identified as crucial negative regulators of various hematop
Characterization of the roles of suppressor of cytokine signaling-3 in prostate cancer development and progression.
Fu X, Ren L, Chen J, Liao K, Fu Y, Qian X, Xiao J. Fu X, et al. Asia Pac J Clin Oncol. 2015 Jun;11(2):106-13. doi: 10.1111/ajco.12357. Epub 2015 Apr 20. Asia Pac J Clin Oncol. 2015. PMID: 25899712 Review.
As negative feedback regulators of cytokine signaling, suppressor of cytokine signaling proteins are induced by interleukins and various peptide hormones and may prevent sustained activation of signaling pathways. In particular, suppre
As negative feedback regulators of cytokine signaling, suppressor of cytokine signaling proteins are indu …
Polymorphisms of suppressor of cytokine signaling-3 associated with susceptibility to tuberculosis among Han Taiwanese.
Lin CJ, Lee SW, Liu CW, Chuu CP, Kao YH, Wu LS. Lin CJ, et al. Cytokine. 2019 Feb;114:11-17. doi: 10.1016/j.cyto.2018.11.026. Epub 2018 Dec 20. Cytokine. 2019. PMID: 30580155
BACKGROUND: Suppressors of cytokine signaling (SOCS), particularly SOCS-3, allow discrimination of patients with active tuberculosis (TB) from healthy subjects in a gender- and age-dependent manner. ...
BACKGROUND: Suppressors of cytokine signaling (SOCS), particularly SOCS-3, allow discrimination of patients with active tuberc …
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