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ACG Clinical Guideline: Primary Sclerosing Cholangitis.
Lindor KD, Kowdley KV, Harrison ME; American College of Gastroenterology. Lindor KD, et al. Am J Gastroenterol. 2015 May;110(5):646-59; quiz 660. doi: 10.1038/ajg.2015.112. Epub 2015 Apr 14. Am J Gastroenterol. 2015. PMID: 25869391
Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver transplantation. ...Complications including portal hypertension, fat-soluble vitamin deficiency, metabolic bone diseases, and devel
Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and may require liver trans
Etiopathogenesis of autoimmune hepatitis.
Floreani A, Restrepo-Jiménez P, Secchi MF, De Martin S, Leung PSC, Krawitt E, Bowlus CL, Gershwin ME, Anaya JM. Floreani A, et al. J Autoimmun. 2018 Dec;95:133-143. doi: 10.1016/j.jaut.2018.10.020. Epub 2018 Oct 29. J Autoimmun. 2018. PMID: 30385083 Review.
Several factors have been described as triggers of autoimmune responses in predisposed individuals, including infections, alcohol, vitamin D deficiency, and an altered composition of the intestinal microbiome. ...
Several factors have been described as triggers of autoimmune responses in predisposed individuals, including infections, alcohol, vitami
Vitamin E deficiency in primary biliary cirrhosis: gastrointestinal malabsorption, frequency and relationship to other lipid-soluble vitamins.
Muñoz SJ, Heubi JE, Balistreri WF, Maddrey WC. Muñoz SJ, et al. Hepatology. 1989 Apr;9(4):525-31. doi: 10.1002/hep.1840090403. Hepatology. 1989. PMID: 2925155
We measured serum vitamin E levels in 45 patients with primary biliary cirrhosis, 20 with primary sclerosing cholangitis, 9 with cryptogenic cirrhosis and 12 with alcoholic cirrhosis. ...Patients with primary biliary cirrhosis and prim
We measured serum vitamin E levels in 45 patients with primary biliary cirrhosis, 20 with primary sclerosing
CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis.
Pender MP. Pender MP. Autoimmune Dis. 2012;2012:189096. doi: 10.1155/2012/189096. Epub 2012 Jan 24. Autoimmune Dis. 2012. PMID: 22312480 Free PMC article.
CD8+ T-cell deficiency is a feature of many chronic autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, systemic sclerosis, dermatomyositis, primary biliary cirrhosis, primary sclerosin
CD8+ T-cell deficiency is a feature of many chronic autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, systemic …
Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis: a Review Featuring a Women's Health Perspective.
Marchioni Beery RM, Vaziri H, Forouhar F. Marchioni Beery RM, et al. J Clin Transl Hepatol. 2014 Dec;2(4):266-84. doi: 10.14218/JCTH.2014.00024. Epub 2014 Dec 15. J Clin Transl Hepatol. 2014. PMID: 26357630 Free PMC article. Review.
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are two major types of chronic cholestatic liver disease. ...In addition to commonly associated manifestations of fatigue, pruritus, and fat-soluble vitamin deficiency
Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are two major types of chronic cholesta
Primary sclerosing cholangitis.
Esber EJ, Ferguson DR. Esber EJ, et al. Gastroenterologist. 1994 Jun;2(2):131-46. Gastroenterologist. 1994. PMID: 8055238 Review.
Primary sclerosing cholangitis (PSC) remains a disease of unknown etiology. The close association of PSC and inflammatory bowel disease (IBD), especially ulcerative colitis (UC), has been reconfirmed in numerous studies. ...Treatment of PSC is symptomatic (pr
Primary sclerosing cholangitis (PSC) remains a disease of unknown etiology. The close association of PSC and inflammato
Serum lipid and fat-soluble vitamin levels in primary sclerosing cholangitis.
Jorgensen RA, Lindor KD, Sartin JS, LaRusso NF, Wiesner RH. Jorgensen RA, et al. J Clin Gastroenterol. 1995 Apr;20(3):215-9. doi: 10.1097/00004836-199504000-00011. J Clin Gastroenterol. 1995. PMID: 7797830 Clinical Trial.
We reviewed the initial lipid and fat-soluble vitamin levels in 56 patients with primary sclerosing cholangitis (PSC) enrolled in a randomized, placebo-controlled trial evaluating ursodeoxycholic acid. ...In patients in the therapeutic trial, vitami
We reviewed the initial lipid and fat-soluble vitamin levels in 56 patients with primary sclerosing cholangitis
The presence of primary sclerosing cholangitis in patients with ileal pouch anal- anastomosis is associated with an additional risk for vitamin D deficiency.
Fialho A, Fialho A, Kochhar G, Shen B. Fialho A, et al. Gastroenterol Rep (Oxf). 2016 Nov;4(4):320-324. doi: 10.1093/gastro/gov035. Epub 2015 Aug 19. Gastroenterol Rep (Oxf). 2016. PMID: 26290513 Free PMC article.
OBJECTIVE: Vitamin D deficiency is common in patients with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC). Whether vitamin D levels are further lowered in patients with concomitant IPAA and primary sclerosing cholangitis
OBJECTIVE: Vitamin D deficiency is common in patients with ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC). Wh …
Improvement in S-cone-mediated visual fields and rod function after correction of vitamin A deficiency.
Hayashi T, Gekka T, Nakano T, Tsuneoka H. Hayashi T, et al. Eur J Ophthalmol. 2011 Sep-Oct;21(5):657-60. doi: 10.5301/EJO.2011.6337. Eur J Ophthalmol. 2011. PMID: 21319138
METHODS: A 65-year-old woman diagnosed with primary sclerosing cholangitis reported experiencing night blindness. The patient underwent comprehensive ophthalmic examination, including funduscopy, ERGs, Humphrey standard automated perimetry (SAP), and short-wa …
METHODS: A 65-year-old woman diagnosed with primary sclerosing cholangitis reported experiencing night blindness. The p …
Severe hypocalcemia following denosumab treatment in a patient with secondary osteoporosis associated with primary sclerosing cholangitis.
Yasuda Y, Iwama S, Arima H. Yasuda Y, et al. Endocr J. 2019 Mar 28;66(3):271-275. doi: 10.1507/endocrj.EJ18-0545. Epub 2019 Feb 2. Endocr J. 2019. PMID: 30713246 Free article.
Primary sclerosing cholangitis (PSC) has been known as a cause of secondary osteoporosis, which often requires medication. Herein, we give the first report of a case of a 38-year-old man with fatigue and paralysis in both upper limbs who had been treated with
Primary sclerosing cholangitis (PSC) has been known as a cause of secondary osteoporosis, which often requires medicati
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