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Page 1
Extravasation emergencies: state-of-the-art management and progress in clinical research.
Pluschnig U, Haslik W, Bartsch R, Mader RM. Pluschnig U, et al. Memo. 2016;9(4):226-230. doi: 10.1007/s12254-016-0304-2. Epub 2016 Dec 5. Memo. 2016. PMID: 28058065 Free PMC article. Review.
In cancer treatment, extravasation is defined as an inadvertent instillation or leakage of cytotoxic drugs into the perivascular space during infusion. ...When a Port-a-Cath extravasation is detected early, a subcutaneous wash-out procedure was found to be beneficia …
In cancer treatment, extravasation is defined as an inadvertent instillation or leakage of cytotoxic drugs into the perivascular spac …
Complete recovery of a wide local reaction by the use of dexrazoxane 72 hours after epirubicin extravasation: case report and review of the literature.
Aigner B, Bauernhofer T, Petru E, Niederkorn A, Arzberger EJ, Richtig E. Aigner B, et al. Dermatology. 2014;229(4):288-92. doi: 10.1159/000365391. Epub 2014 Nov 27. Dermatology. 2014. PMID: 25472626 Review.
CASE REPORT: We report on a 63-year-old female patient with breast cancer treated with epirubicin combination therapy. She experienced extravasation on the distal right arm at the end of the very first cycle, being initially treated with dimethylsulfoxide 99% topica …
CASE REPORT: We report on a 63-year-old female patient with breast cancer treated with epirubicin combination therapy. She experience …
Extravasation of Epirubicin chemotherapy from a port-a-cath causing extensive breast necrosis: Sequential imaging findings and management of a breast cancer patient.
Moyle P, Soh C, Healy N, Malata C, Forouhi P. Moyle P, et al. Radiol Case Rep. 2021 Sep 10;16(11):3509-3514. doi: 10.1016/j.radcr.2021.08.046. eCollection 2021 Nov. Radiol Case Rep. 2021. PMID: 34552682 Free PMC article.
Extravasation of chemotherapy is rare with an estimated incidence of 0.01%-7% but can cause significant morbidity, delay in cancer treatment and potential mortality. We present a case of 55-year-old woman with a metastatic right axillary lymph node with no identifiable bre …
Extravasation of chemotherapy is rare with an estimated incidence of 0.01%-7% but can cause significant morbidity, delay in cancer tr …
Tissue distribution of epirubicin after severe extravasation in humans.
Nedomansky J, Haslik W, Pluschnig U, Kornauth C, Deutschmann C, Hacker S, Steger GG, Bartsch R, Mader RM. Nedomansky J, et al. Cancer Chemother Pharmacol. 2021 Aug;88(2):203-209. doi: 10.1007/s00280-021-04280-8. Epub 2021 Apr 27. Cancer Chemother Pharmacol. 2021. PMID: 33907881 Free PMC article.
METHODS: From six patients scheduled for surgery, removed tissue flaps were systematically analysed by HPLC (epirubicin: 5 subjects; doxorubicin: 1 subject). RESULTS: After extravasation, tissue concentrations were highly variable with an individual anthracycline di …
METHODS: From six patients scheduled for surgery, removed tissue flaps were systematically analysed by HPLC (epirubicin: 5 subjects; …
Epirubicin extravasation: consequences of delayed management.
Hale O, Deutsch PG, Lahiri A. Hale O, et al. BMJ Case Rep. 2017 Jan 6;2017:bcr2016218012. doi: 10.1136/bcr-2016-218012. BMJ Case Rep. 2017. PMID: 28062432 Free PMC article.
Epirubicin is an anthracycline chemotherapy agent used for treatment of several cancers including oesophageal, breast and gastric. ...Signs of the injury can be subtle and without prompt recognition and treatment there can be extensive tissue damage and depending on locati …
Epirubicin is an anthracycline chemotherapy agent used for treatment of several cancers including oesophageal, breast and gastric. .. …
Intrapleural extravasation of epirubicin, 5-fluouracil, and cyclophosphamide, treated with dexrazoxane.
Uges JW, Vollaard AM, Wilms EB, Brouwer RE. Uges JW, et al. Int J Clin Oncol. 2006 Dec;11(6):467-70. doi: 10.1007/s10147-006-0598-x. Epub 2006 Dec 25. Int J Clin Oncol. 2006. PMID: 17180516
The extravasation of DNA-binding vesicant drugs, such as epirubicin, is a feared complication of chemotherapy and can lead to extensive damage at injury sites. We describe a 56-year-old woman with breast cancer who received adjuvant chemotherapy after a breast-prese …
The extravasation of DNA-binding vesicant drugs, such as epirubicin, is a feared complication of chemotherapy and can lead to …
Surgical management after doxorubicin and epirubicin extravasation.
Heitmann C, Durmus C, Ingianni G. Heitmann C, et al. J Hand Surg Br. 1998 Oct;23(5):666-8. doi: 10.1016/s0266-7681(98)80024-7. J Hand Surg Br. 1998. PMID: 9821616
Doxorubicin and epirubicin are strong antineoplastic agents widely used in chemotherapy. ...In cases of doxorubicin and epirubicin extravasation it is very important to perform an early extensive surgical debridement with delayed closure to avoid long hospita …
Doxorubicin and epirubicin are strong antineoplastic agents widely used in chemotherapy. ...In cases of doxorubicin and epirubicin …
Negative-pressure wound therapy and early pedicle flap reconstruction of the chest wall after epirubicin extravasation.
Papadakis M, Rahmanian-Schwarz A, Bednarek M, Arafkas M, Holschneider P, Hübner G. Papadakis M, et al. J Vasc Access. 2017 May 15;18(3):e27-e29. doi: 10.5301/jva.5000654. J Vasc Access. 2017. PMID: 28165571
The aim of this work is to present a combination therapy for chest wall reconstruction following epirubicin extravasation. METHODS: Herein, we report a 68-year-old woman with massive soft tissue necrosis of the anterolateral chest wall after epirubicin ext …
The aim of this work is to present a combination therapy for chest wall reconstruction following epirubicin extravasation. MET …
Treatment of experimental extravasation of amrubicin, liposomal doxorubicin, and mitoxantrone with dexrazoxane.
Langer SW, Thougaard AV, Sehested M, Jensen PB. Langer SW, et al. Cancer Chemother Pharmacol. 2012 Feb;69(2):573-6. doi: 10.1007/s00280-011-1794-6. Epub 2011 Dec 6. Cancer Chemother Pharmacol. 2012. PMID: 22143379
PURPOSE: Dexrazoxane is an established treatment option in extravasation of the classic anthracyclines such as doxorubicin, epirubicin, and daunorubicin. ...METHODS: A total of 80 female B6D2F1 mice were tested in an established mouse extravasation model. The …
PURPOSE: Dexrazoxane is an established treatment option in extravasation of the classic anthracyclines such as doxorubicin, epirub …
Management of extravasation injuries.
Kumar RJ, Pegg SP, Kimble RM. Kumar RJ, et al. ANZ J Surg. 2001 May;71(5):285-9. doi: 10.1046/j.1440-1622.2001.02104.x. ANZ J Surg. 2001. PMID: 11374477 Review.
BACKGROUND: Various agents have been implicated in causing tissue necrosis after intravenous infusions have extravasated. These include solutions of calcium, potassium, bicarbonate, hypertonic dextrose, cytotoxic drugs and antibiotics. ...METHODS: A retrospective review wa …
BACKGROUND: Various agents have been implicated in causing tissue necrosis after intravenous infusions have extravasated. These inclu …
50 results