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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2009 1
2010 4
2011 3
2012 2
2013 1
2014 3
2015 4
2016 8
2017 6
2018 6
2019 5
2020 4
2021 3
2022 3
2023 0
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45 results
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Page 1
Risk of infections using anti-TNF agents in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: a systematic review and meta-analysis.
Minozzi S, Bonovas S, Lytras T, Pecoraro V, González-Lorenzo M, Bastiampillai AJ, Gabrielli EM, Lonati AC, Moja L, Cinquini M, Marino V, Matucci A, Milano GM, Tocci G, Scarpa R, Goletti D, Cantini F. Minozzi S, et al. Expert Opin Drug Saf. 2016 Dec;15(sup1):11-34. doi: 10.1080/14740338.2016.1240783. Expert Opin Drug Saf. 2016. PMID: 27924643 Free article. Review.
Areas covered: We conducted a systematic review and meta-analysis of published randomized studies to determine the effect of anti-TNF drugs on the occurrence of infectious adverse events (serious infections; tuberculosis; opportunistic infections; any infe …
Areas covered: We conducted a systematic review and meta-analysis of published randomized studies to determine the effect of anti-TNF drugs …
Comparative risk of serious infections among real-world users of biologics for psoriasis or psoriatic arthritis.
Li X, Andersen KM, Chang HY, Curtis JR, Alexander GC. Li X, et al. Ann Rheum Dis. 2020 Feb;79(2):285-291. doi: 10.1136/annrheumdis-2019-216102. Epub 2019 Oct 31. Ann Rheum Dis. 2020. PMID: 31672774 Free PMC article.
OBJECTIVE: To examine whether initiation of interleukin (IL)-17, IL-12/23 or tumour necrosis factor (TNF) inhibitor is associated with an increased risk of serious infection among real-world psoriasis (PsO) or psoriatic arthritis (PsA) patients. ...By contras …
OBJECTIVE: To examine whether initiation of interleukin (IL)-17, IL-12/23 or tumour necrosis factor (TNF) inhibitor is associated with an in …
Biologic Therapies and Risk of Infection and Malignancy in Patients With Inflammatory Bowel Disease: A Systematic Review and Network Meta-analysis.
Bonovas S, Fiorino G, Allocca M, Lytras T, Nikolopoulos GK, Peyrin-Biroulet L, Danese S. Bonovas S, et al. Clin Gastroenterol Hepatol. 2016 Oct;14(10):1385-1397.e10. doi: 10.1016/j.cgh.2016.04.039. Epub 2016 May 14. Clin Gastroenterol Hepatol. 2016. PMID: 27189910 Review.
Two reviewers independently extracted study data and outcomes (serious infections, opportunistic infections, tuberculosis, any infection, and malignancies) and rated each trial's risk of bias. ...CONCLUSIONS: On the basis of a systematic …
Two reviewers independently extracted study data and outcomes (serious infections, opportunistic infections, tuberculos …
Overall and comparative safety of biologic and immunosuppressive therapy in inflammatory bowel diseases.
Holmer A, Singh S. Holmer A, et al. Expert Rev Clin Immunol. 2019 Sep;15(9):969-979. doi: 10.1080/1744666X.2019.1646127. Epub 2019 Jul 25. Expert Rev Clin Immunol. 2019. PMID: 31322018 Free PMC article. Review.
While several randomized trials and indirect comparisons have informed the comparative efficacy of medications, there has been a limited synthesis of safety of different agents. Areas covered: We focus on the overall and comparative risk of serious and opportunistic …
While several randomized trials and indirect comparisons have informed the comparative efficacy of medications, there has been a limited syn …
Adverse effects of biologics: a network meta-analysis and Cochrane overview.
Singh JA, Wells GA, Christensen R, Tanjong Ghogomu E, Maxwell L, Macdonald JK, Filippini G, Skoetz N, Francis D, Lopes LC, Guyatt GH, Schmitt J, La Mantia L, Weberschock T, Roos JF, Siebert H, Hershan S, Lunn MP, Tugwell P, Buchbinder R. Singh JA, et al. Cochrane Database Syst Rev. 2011 Feb 16;2011(2):CD008794. doi: 10.1002/14651858.CD008794.pub2. Cochrane Database Syst Rev. 2011. PMID: 21328309 Free PMC article. Review.
Certolizumab pegol was associated with significantly higher risk of serious infections compared to control treatment (OR 3.51, 95% CI 1.59 to 7.79; NNTH = 17, 95% CI 7 to 68). ...Although the overall numbers are relatively small, certolizumab pegol was associ …
Certolizumab pegol was associated with significantly higher risk of serious infections compared to control treatment (O …
Risk of serious infections in biological treatment of patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a meta-analysis.
Wang S, He Q, Shuai Z. Wang S, et al. Clin Rheumatol. 2018 Feb;37(2):439-450. doi: 10.1007/s10067-017-3966-1. Epub 2017 Dec 30. Clin Rheumatol. 2018. PMID: 29290076
The risk of serious infections has no difference and numerically was only slightly increased in patients with AS and nr-axSpA treated by biologics compared with controls (OR = 1.42; 95%CI 0.58-3.47). ...The use of biologics among patients with AS and nr-axSpA …
The risk of serious infections has no difference and numerically was only slightly increased in patients with AS and nr …
Risk of Adverse Events After Anti-TNF Treatment for Inflammatory Rheumatological Disease. A Meta-Analysis.
Li J, Zhang Z, Wu X, Zhou J, Meng D, Zhu P. Li J, et al. Front Pharmacol. 2021 Nov 1;12:746396. doi: 10.3389/fphar.2021.746396. eCollection 2021. Front Pharmacol. 2021. PMID: 34790122 Free PMC article. Review.
A total of 23 articles were used for meta-analysis. The Cochrane Collaboration's risk of bias tool was used to assess the methodological quality of the included studies. ...Results: Treatment with anti-TNFalpha agents resulted in an increase in the risk of …
A total of 23 articles were used for meta-analysis. The Cochrane Collaboration's risk of bias tool was used to assess the meth …
Herpes zoster: Risk and prevention during immunomodulating therapy.
Tran CT, Ducancelle A, Masson C, Lunel-Fabiani F. Tran CT, et al. Joint Bone Spine. 2017 Jan;84(1):21-27. doi: 10.1016/j.jbspin.2016.04.001. Epub 2016 May 28. Joint Bone Spine. 2017. PMID: 27245419 Free article. Review.
Immunomodulating drugs can increase the risk of infection. Well-established risk factors include advanced age and glucocorticoid therapy. The data are somewhat conflicting for medications such as methotrexate, tofacitinib, TNFalpha antagonists (infliximab, ad …
Immunomodulating drugs can increase the risk of infection. Well-established risk factors include advanced age and gluco …
The Risk of Adverse Effects of TNF-α Inhibitors in Patients With Rheumatoid Arthritis: A Network Meta-Analysis.
He B, Li Y, Luo WW, Cheng X, Xiang HR, Zhang QZ, He J, Peng WX. He B, et al. Front Immunol. 2022 Feb 16;13:814429. doi: 10.3389/fimmu.2022.814429. eCollection 2022. Front Immunol. 2022. PMID: 35250992 Free PMC article.
In infections, comparisons between treatments showed adalimumab combined DMARDs (0.59, 95% CI: 0.37, 0.95), etanercept (0.49, 95% CI: 0.28, 0.88), etanercept combined DMARDs (0.56, 95% CI: 0.35, 0.91), golimumab combined DMARDs (0.51, 95% CI: 0.31, 0.83) decreased t …
In infections, comparisons between treatments showed adalimumab combined DMARDs (0.59, 95% CI: 0.37, 0.95), etanercept (0.49, 95% CI: …
Safety of synthetic and biological DMARDs: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis.
Ramiro S, Gaujoux-Viala C, Nam JL, Smolen JS, Buch M, Gossec L, van der Heijde D, Winthrop K, Landewé R. Ramiro S, et al. Ann Rheum Dis. 2014 Mar;73(3):529-35. doi: 10.1136/annrheumdis-2013-204575. Epub 2014 Jan 8. Ann Rheum Dis. 2014. PMID: 24401994 Review.
Patients on tumour necrosis factor inhibitors (TNFi) compared to patients on conventional sDMARDs had a higher risk of serious infections (adjusted HR (aHR) 1.1-1.8), a higher risk of tuberculosis, and an increased risk of infection by he …
Patients on tumour necrosis factor inhibitors (TNFi) compared to patients on conventional sDMARDs had a higher risk of serious …
45 results