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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 3
1986 1
1991 2
1998 1
1999 1
2001 2
2002 3
2003 1
2004 2
2006 1
2007 1
2008 1
2009 2
2010 1
2011 3
2012 1
2013 3
2014 1
2015 4
2016 3
2017 3
2018 3
2020 2
2021 1
2023 0
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41 results
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Page 1
Preparation and Evaluation of Midazolam Rectal Gel in vitro and in vivo.
Chen X, Li W, Li Y, Guo F, Zhang H, Gao J, Sun J, Zheng A. Chen X, et al. Drug Res (Stuttg). 2018 Oct;68(10):560-566. doi: 10.1055/a-0589-9886. Epub 2018 Apr 9. Drug Res (Stuttg). 2018. PMID: 29631297
Midazolam has been successfully used for sedation, which the tablets, injections and oral solutions were available in market. However, the oral bioavailability of midazolam is less due to the first effect, while injection formulation has a low p
Midazolam has been successfully used for sedation, which the tablets, injections and oral solutions were available in market.
Avoiding the incompatibility of peripheral parenteral nutrition solution and midazolam injection for intravenous sedation.
Futamura A, Higashiguchi T, Chihara T, Yokota Y, Itani Y. Futamura A, et al. Fujita Med J. 2021;7(2):35-40. doi: 10.20407/fmj.2020-005. Epub 2020 Oct 10. Fujita Med J. 2021. PMID: 35111542 Free PMC article.
The aim of the current study was to determine how to avoid compound changes when co-administering a midazolam injection and a PPN solution. METHODS: Midazolam solutions were prepared by diluting a midazolam injection with a 5% glucose intravenou …
The aim of the current study was to determine how to avoid compound changes when co-administering a midazolam injection and a …
Midazolam: pharmacology and uses.
Reves JG, Fragen RJ, Vinik HR, Greenblatt DJ. Reves JG, et al. Anesthesiology. 1985 Mar;62(3):310-24. Anesthesiology. 1985. PMID: 3156545 Review.
It is water soluble in its acid formulation but is highly lipid soluble in vivo. Midazolam also has a relatively rapid onset of action and high metabolic clearance when compared with other benzodiazepines. ...Midazolam should be a useful addition to the formu …
It is water soluble in its acid formulation but is highly lipid soluble in vivo. Midazolam also has a relatively rapid onset o …
Oral mucosal drug delivery: clinical pharmacokinetics and therapeutic applications.
Zhang H, Zhang J, Streisand JB. Zhang H, et al. Clin Pharmacokinet. 2002;41(9):661-80. doi: 10.2165/00003088-200241090-00003. Clin Pharmacokinet. 2002. PMID: 12126458 Review.
Oral mucosal drug delivery is an alternative method of systemic drug delivery that offers several advantages over both injectable and enteral methods. ...Not all drugs, however, can be administered through the oral mucosa because of the characteristics of the …
Oral mucosal drug delivery is an alternative method of systemic drug delivery that offers several advantages over both inje
The Emergence of Second-Generation Lethal Injection Protocols: A Brief History and Review.
Malcom DR, Romanelli F. Malcom DR, et al. Pharmacotherapy. 2017 Oct;37(10):1249-1257. doi: 10.1002/phar.2011. Epub 2017 Oct 2. Pharmacotherapy. 2017. PMID: 28801944 Review.
U.S. Supreme Court decisions, including Baze v. Rees (2008) and Glossip v. Gross (2015), have evaluated and condoned lethal injection protocols. Despite the judicial validation of some midazolam-containing protocols, controversy exists about the level of unco …
U.S. Supreme Court decisions, including Baze v. Rees (2008) and Glossip v. Gross (2015), have evaluated and condoned lethal inject
Pharmacokinetics and tolerability of intranasal diazepam and midazolam in healthy adult volunteers.
Ivaturi VD, Riss JR, Kriel RL, Cloyd JC. Ivaturi VD, et al. Acta Neurol Scand. 2009 Nov;120(5):353-7. doi: 10.1111/j.1600-0404.2009.01170.x. Epub 2009 May 14. Acta Neurol Scand. 2009. PMID: 19456308
OBJECTIVE: The purpose of this pilot study was to determine the pharmacokinetics and tolerability of an investigational diazepam (DZP) formulation and a parenteral midazolam (MDZ) formulation following intranasal (i.n.) administration for the efficient treatm …
OBJECTIVE: The purpose of this pilot study was to determine the pharmacokinetics and tolerability of an investigational diazepam (DZP) fo
Pharmacokinetics and pharmacodynamics of nasally delivered midazolam.
Haschke M, Suter K, Hofmann S, Witschi R, Fröhlich J, Imanidis G, Drewe J, Briellmann TA, Dussy FE, Krähenbühl S, Surber C. Haschke M, et al. Br J Clin Pharmacol. 2010 Jun;69(6):607-16. doi: 10.1111/j.1365-2125.2010.03611.x. Br J Clin Pharmacol. 2010. PMID: 20565452 Free PMC article.
AIMS: To investigate the pharmacokinetics and pharmacodynamics of nasal formulations containing midazolam (5-30 mg ml(-1)) complexed with cyclodextrin. ...The pharmacodynamic effects after the low-dose nasal formulations were comparable with those after 1 mg …
AIMS: To investigate the pharmacokinetics and pharmacodynamics of nasal formulations containing midazolam (5-30 mg ml(-1)) com …
Intranasal administration of midazolam in a cyclodextrin based formulation: bioavailability and clinical evaluation in humans.
Gudmundsdottir H, Sigurjonsdottir JF, Masson M, Fjalldal O, Stefansson E, Loftsson T. Gudmundsdottir H, et al. Pharmazie. 2001 Dec;56(12):963-6. Pharmazie. 2001. PMID: 11802661 Clinical Trial.
In this study midazolam was formulated in aqueous sulfobutylether-beta-cyclodextrin buffer solution. ...The absolute bioavailability of midazolam in the nasal formulation was determined to be 64 +/- 19% (mean +/- standard deviation). ...
In this study midazolam was formulated in aqueous sulfobutylether-beta-cyclodextrin buffer solution. ...The absolute bioavaila …
Effect of saquinavir on the pharmacokinetics and pharmacodynamics of oral and intravenous midazolam.
Palkama VJ, Ahonen J, Neuvonen PJ, Olkkola KT. Palkama VJ, et al. Clin Pharmacol Ther. 1999 Jul;66(1):33-9. doi: 10.1016/S0009-9236(99)70051-2. Clin Pharmacol Ther. 1999. PMID: 10430107 Clinical Trial.
On day 5, the subjects who had received oral midazolam on day 3 received intravenously midazolam and vice versa. ...After intravenous midazolam, only the subjective feeling of drug effect was increased significantly (P < .05) by saquinavir. ...
On day 5, the subjects who had received oral midazolam on day 3 received intravenously midazolam and vice versa. ...After intr …
The compatibility and stability of midazolam and dexamethasone in infusion solutions.
Good PD, Schneider JJ, Ravenscroft PJ. Good PD, et al. J Pain Symptom Manage. 2004 May;27(5):471-5. doi: 10.1016/j.jpainsymman.2004.02.002. J Pain Symptom Manage. 2004. PMID: 15120775 Free article.
This study demonstrates that cloudiness of a solution is not the only predictor of drug loss and that drug loss may occur even in solutions that remain clear at time of preparation. The clinical implications of these results are that dexamethasone and midazolam
This study demonstrates that cloudiness of a solution is not the only predictor of drug loss and that drug loss may occur even …
41 results