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Page 1
Mucoactive agents for chronic, non-cystic fibrosis lung disease: A systematic review and meta-analysis.
Tarrant BJ, Le Maitre C, Romero L, Steward R, Button BM, Thompson BR, Holland AE. Tarrant BJ, et al. Respirology. 2017 Aug;22(6):1084-1092. doi: 10.1111/resp.13047. Epub 2017 Apr 11. Respirology. 2017. PMID: 28397992 Free article. Review.
Inhaled mucoactive agents are used in respiratory disease to improve mucus properties and enhance secretion clearance. ...Mannitol improved mucociliary clearance in asthma and bronchiectasis, while the effects of N-acetylcysteine were unclear. In chronic lung diseas
Inhaled mucoactive agents are used in respiratory disease to improve mucus properties and enhance secretion clearance. ...Mannitol im
H2 Inhibits the Formation of Neutrophil Extracellular Traps.
Shirakawa K, Kobayashi E, Ichihara G, Kitakata H, Katsumata Y, Sugai K, Hakamata Y, Sano M. Shirakawa K, et al. JACC Basic Transl Sci. 2022 Jan 12;7(2):146-161. doi: 10.1016/j.jacbts.2021.11.005. eCollection 2022 Feb. JACC Basic Transl Sci. 2022. PMID: 35257042 Free PMC article.
H(2) suppressed both myeloperoxidase chlorination activity and production of reactive oxygen species to the same degree as N-acetylcysteine and ascorbic acid, while showing a more potent ability to inhibit NET formation than these antioxidants do in PMA-stimulated neutroph …
H(2) suppressed both myeloperoxidase chlorination activity and production of reactive oxygen species to the same degree as N-acetylcystei
Development of spray-dried N-acetylcysteine dry powder for inhalation.
Mancini L, Paolantoni M, Schoubben A, Ricci M. Mancini L, et al. Int J Pharm. 2023 Jan 25;631:122550. doi: 10.1016/j.ijpharm.2022.122550. Epub 2022 Dec 25. Int J Pharm. 2023. PMID: 36577481
N-acetylcysteine (NAC) has both antioxidant and immunomodulatory activities and has been used as adjuvant therapy in several viral infections. Recently, NAC attracted attention for its possible role in reducing the affinity of the spike protein receptor binding domain to a …
N-acetylcysteine (NAC) has both antioxidant and immunomodulatory activities and has been used as adjuvant therapy in several viral in …
Stability of acetylcysteine solution repackaged in oral syringes and associated cost savings.
Kiser TH, Oldland AR, Fish DN. Kiser TH, et al. Am J Health Syst Pharm. 2007 Apr 1;64(7):762-6. doi: 10.2146/ajhp060425. Am J Health Syst Pharm. 2007. PMID: 17384363
METHODS: Acetylcysteine 20% solution for inhalation was repackaged undiluted as 600 mg/3 mL in capped oral syringes and stored either under refrigeration or at room temperature exposed to fluorescent light. ...RESULTS: Acetylcysteine solution in …
METHODS: Acetylcysteine 20% solution for inhalation was repackaged undiluted as 600 mg/3 mL in capped oral syringes and …
Chemical and physical compatibility of levalbuterol inhalation solution concentrate mixed with budesonide, ipratropium bromide, cromolyn sodium, or acetylcysteine sodium.
Bonasia PJ, McVicar WK, Bill W, Ong S. Bonasia PJ, et al. Respir Care. 2008 Dec;53(12):1716-22. Respir Care. 2008. PMID: 19025708 Free article.
OBJECTIVE: To determine the chemical and physical compatibility of levalbuterol with ipratropium bromide, cromolyn sodium, acetylcysteine sodium, and budesonide. METHODS: We mixed one dose of levalbuterol inhalation solution concentrate (1.25 mg/0.5 mL) with …
OBJECTIVE: To determine the chemical and physical compatibility of levalbuterol with ipratropium bromide, cromolyn sodium, acetylcysteine
A clinical and pharmacoeconomic justification for intravenous acetylcysteine: a US perspective.
Culley CM, Krenzelok EP. Culley CM, et al. Toxicol Rev. 2005;24(2):131-43. doi: 10.2165/00139709-200524020-00007. Toxicol Rev. 2005. PMID: 16180933 Review.
Until the recent approval of intravenous acetylcysteine in the US, it was necessary to compound the oral solution for intravenous administration. ...Intravenous acetylcysteine may be preferred over oral administration based on improved tolerabil …
Until the recent approval of intravenous acetylcysteine in the US, it was necessary to compound the oral solution for intraven …
Stability and microbiology of inhalant N-acetylcysteine used as an intravenous solution for the treatment of acetaminophen poisoning.
Dribben WH, Porto SM, Jeffords BK. Dribben WH, et al. Ann Emerg Med. 2003 Jul;42(1):9-13. doi: 10.1067/mem.2003.231. Ann Emerg Med. 2003. PMID: 12827116
In the United States, only the oral administration of N-acetylcysteine is approved by the US Food and Drug Administration. ...METHODS: A total of 8 N-acetylcysteine solutions (solution A through H) were prepared by injecting 150 mL of 20% …
In the United States, only the oral administration of N-acetylcysteine is approved by the US Food and Drug Administration
Effectiveness of nebulized N-acetylcysteine solution in children with acute bronchiolitis.
Naz F, Raza AB, Ijaz I, Kazi MY. Naz F, et al. J Coll Physicians Surg Pak. 2014 Jun;24(6):408-11. J Coll Physicians Surg Pak. 2014. PMID: 24953914 Clinical Trial.
PLACE AND DURATION OF STUDY: Paediatric Medical Unit of the Children's Hospital and the Institute of Child Health, Lahore, from November 2011 to April 2012. ...At day 3 and 5, it was 2.9 1.48 and 3.30 1.77 in group-1 and 0.88 1.08 and 1.90 1.32 in group-2 respectively. The …
PLACE AND DURATION OF STUDY: Paediatric Medical Unit of the Children's Hospital and the Institute of Child Health, Lahore, from Novem …
Compatibility and osmolality of inhaled N-acetylcysteine nebulizing solution with fenoterol and ipratropium.
Lee TY, Chen CM, Lee CN, Chiang YC, Chen HY. Lee TY, et al. Am J Health Syst Pharm. 2005 Apr 15;62(8):828-33. doi: 10.1093/ajhp/62.8.828. Am J Health Syst Pharm. 2005. PMID: 15821276
PURPOSE: The compatibility, pH, and osmolality of N-acetylcysteine (NAC) nebulizing solution in the presence of ipratropium bromide or fenoterol hydrobromide were studied. ...Osmolality was measured by sampling 100 microL from the filling cup at a five-minute interv …
PURPOSE: The compatibility, pH, and osmolality of N-acetylcysteine (NAC) nebulizing solution in the presence of ipratropium br …
Effects of Different Inhalation Therapy on Ventilator-Associated Pneumonia in Ventilated COVID-19 Patients: A Randomized Controlled Trial.
Delić N, Matetic A, Domjanović J, Kljaković-Gašpić T, Šarić L, Ilić D, Došenović S, Domazet J, Kovač R, Runjić F, Stipić SS, Duplančić B. Delić N, et al. Microorganisms. 2022 May 28;10(6):1118. doi: 10.3390/microorganisms10061118. Microorganisms. 2022. PMID: 35744636 Free PMC article.
The effect of routine inhalation therapy on ventilator-associated pneumonia (VAP) in mechanically ventilated patients with the coronavirus disease (COVID-19) has not been well-defined. ...Patients were randomized and allocated to a control group (no routine inhalation
The effect of routine inhalation therapy on ventilator-associated pneumonia (VAP) in mechanically ventilated patients with the corona …
50 results