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Year Number of Results
1968 1
1970 1
1971 4
1972 8
1973 8
1974 20
1975 41
1976 45
1977 45
1978 48
1979 63
1980 70
1981 83
1982 100
1983 112
1984 117
1985 137
1986 150
1987 173
1988 157
1989 164
1990 154
1991 157
1992 138
1993 148
1994 193
1995 201
1996 195
1997 201
1998 283
1999 272
2000 314
2001 272
2002 336
2003 336
2004 318
2005 372
2006 396
2007 410
2008 414
2009 394
2010 415
2011 417
2012 432
2013 375
2014 416
2015 392
2016 402
2017 385
2018 343
2019 334
2020 382
2021 375
2022 364
2023 362
2024 343
2025 2

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12,002 results

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Page 1
Herpes Simplex Virus: The Interplay Between HSV, Host, and HIV-1.
Desai DV, Kulkarni SS. Desai DV, et al. Viral Immunol. 2015 Dec;28(10):546-55. doi: 10.1089/vim.2015.0012. Epub 2015 Sep 2. Viral Immunol. 2015. PMID: 26331265 Review.
Genital ulceration due to herpes simplex virus type 2 (HSV-2) infections is an important clinical manifestation reported to increase the risk of human immunodeficiency virus type 1 (HIV-1) acquisition and replication in HIV-1/HSV-2 coinfection. ...Alth …
Genital ulceration due to herpes simplex virus type 2 (HSV-2) infections is an important clinical manifestation reported to in …
Therapeutic HSV-2 vaccine decreases recurrent virus shedding and recurrent genital herpes disease.
Bernstein DI, Flechtner JB, McNeil LK, Heineman T, Oliphant T, Tasker S, Wald A, Hetherington S; Genocea study group. Bernstein DI, et al. Vaccine. 2019 Jun 6;37(26):3443-3450. doi: 10.1016/j.vaccine.2019.05.009. Epub 2019 May 15. Vaccine. 2019. PMID: 31103365 Clinical Trial.
GEN-003 is a candidate therapeutic vaccine containing 2 HSV-2 proteins, gD2 and ICP4, and Matrix-M2 adjuvant (M2). METHODS: HSV-2 seropositive persons with genital herpes were randomized into three dose cohorts of Gen-003 (60 g antigen/50 g M2, 60 g/75 …
GEN-003 is a candidate therapeutic vaccine containing 2 HSV-2 proteins, gD2 and ICP4, and Matrix-M2 adjuvant (M2). METHODS: …
HSV-2 transmission.
Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. Sacks SL, et al. Antiviral Res. 2004 Aug;63 Suppl 1:S27-35. doi: 10.1016/j.antiviral.2004.06.005. Antiviral Res. 2004. PMID: 15450383 Review.
A number of important risk factors for the acquisition of HSV-2 have been established including female gender, black or Hispanic ethnic origin, HIV infection, age, and increased number of sexual partners. ...
A number of important risk factors for the acquisition of HSV-2 have been established including female gender, black or Hispan …
HSV shedding.
Sacks SL, Griffiths PD, Corey L, Cohen C, Cunningham A, Dusheiko GM, Self S, Spruance S, Stanberry LR, Wald A, Whitley RJ. Sacks SL, et al. Antiviral Res. 2004 Aug;63 Suppl 1:S19-26. doi: 10.1016/j.antiviral.2004.06.004. Antiviral Res. 2004. PMID: 15450382 Review.
However, the relationship between shedding frequency, viral titer and transmission is unknown. HSV-2 shedding is affected by the site and time since acquisition of infection. The advent of sensitive PCR techniques has shown that the magnitude and frequency of viral …
However, the relationship between shedding frequency, viral titer and transmission is unknown. HSV-2 shedding is affected by t …
Genital HSV-1 infections.
Wald A. Wald A. Sex Transm Infect. 2006 Jun;82(3):189-90. doi: 10.1136/sti.2006.019935. Sex Transm Infect. 2006. PMID: 16731663 Free PMC article.
Importantly, individuals with genital HSV-1 are still at risk of HSV-2 acquisition...
Importantly, individuals with genital HSV-1 are still at risk of HSV-2 acquisition...
Herpes simplex virus 2 (HSV-2) evolves faster in cell culture than HSV-1 by generating greater genetic diversity.
López-Muñoz AD, Rastrojo A, Martín R, Alcamí A. López-Muñoz AD, et al. PLoS Pathog. 2021 Aug 26;17(8):e1009541. doi: 10.1371/journal.ppat.1009541. eCollection 2021 Aug. PLoS Pathog. 2021. PMID: 34437654 Free PMC article.
Herpes simplex virus type 1 and 2 (HSV-1 and HSV-2, respectively) are prevalent human pathogens of clinical relevance that establish long-life latency in the nervous system. ...This might have contributed to the evolutionary divergence of HSV-1 and HSV-2 …
Herpes simplex virus type 1 and 2 (HSV-1 and HSV-2, respectively) are prevalent human pathogens of clinical relevance that est …
Herpes Simplex Virus Mistyping due to HSV-1 HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B.
Casto AM, Huang MW, Xie H, Jerome KR, Wald A, Johnston CM, Greninger AL. Casto AM, et al. Viruses. 2020 Aug 6;12(8):860. doi: 10.3390/v12080860. Viruses. 2020. PMID: 32781734 Free PMC article.
Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 and HSV-2 are distinguished in clinical settings using sequence-based "typing" assays. Here we describe a case of HSV mistyping …
Human herpes simplex viruses (HSV) 1 and 2 are extremely common human pathogens with overlapping disease spectra. Infections due to HSV-1 an …
Meeting report: Initial World Health Organization consultation on herpes simplex virus (HSV) vaccine preferred product characteristics, March 2017.
Gottlieb SL, Giersing BK, Hickling J, Jones R, Deal C, Kaslow DC; HSV Vaccine Expert Consultation Group. Gottlieb SL, et al. Vaccine. 2019 Nov 28;37(50):7408-7418. doi: 10.1016/j.vaccine.2017.10.084. Epub 2017 Dec 8. Vaccine. 2019. PMID: 29224963 Review.
Meeting participants outlined an initial set of overarching public health goals for HSV vaccines in LMICs, which are: to reduce the acquisition of HIV associated with HSV-2 infection in high HIV-prevalence populations and to reduce the burden of HSV-associated disea …
Meeting participants outlined an initial set of overarching public health goals for HSV vaccines in LMICs, which are: to reduce the acquisit …
Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1.
Yu X, Li Y, Chen Q, Su C, Zhang Z, Yang C, Hu Z, Hou J, Zhou J, Gong L, Jiang X, Zheng C, He S. Yu X, et al. J Virol. 2015 Nov 11;90(2):1088-95. doi: 10.1128/JVI.02446-15. Print 2016 Jan 15. J Virol. 2015. PMID: 26559832 Free PMC article.
Similar to HSV-1, HSV-2 infection triggered programmed necrosis in mouse cells. However, neither HSV-1 nor HSV-2 infection was able to induce programmed necrosis in human cells. Moreover, HSV-1 or HSV-2 infection in human cells blocked tu …
Similar to HSV-1, HSV-2 infection triggered programmed necrosis in mouse cells. However, neither HSV-1 nor HSV-2 …
12,002 results
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