Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1989 4
1990 13
1991 21
1992 58
1993 123
1994 193
1995 288
1996 329
1997 407
1998 498
1999 679
2000 843
2001 1068
2002 1203
2003 1294
2004 1454
2005 1584
2006 1666
2007 1737
2008 1833
2009 1924
2010 2049
2011 2052
2012 2337
2013 2524
2014 2643
2015 2702
2016 2655
2017 2639
2018 2875
2019 3187
2020 3353
2021 3338
2022 4794
2023 4591
2024 3330
2025 395

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

55,491 results

Results by year

Filters applied: . Clear all
Page 1
PI3K inhibitors are finally coming of age.
Vanhaesebroeck B, Perry MWD, Brown JR, André F, Okkenhaug K. Vanhaesebroeck B, et al. Nat Rev Drug Discov. 2021 Oct;20(10):741-769. doi: 10.1038/s41573-021-00209-1. Epub 2021 Jun 14. Nat Rev Drug Discov. 2021. PMID: 34127844 Free PMC article. Review.
Phosphatidylinositol 3-kinase: the oncoprotein.
Vogt PK, Hart JR, Gymnopoulos M, Jiang H, Kang S, Bader AG, Zhao L, Denley A. Vogt PK, et al. Curr Top Microbiol Immunol. 2010;347:79-104. doi: 10.1007/82_2010_80. Curr Top Microbiol Immunol. 2010. PMID: 20582532 Free PMC article. Review.
Rare cancer-specific mutations in PIK3CA show gain of function.
Gymnopoulos M, Elsliger MA, Vogt PK. Gymnopoulos M, et al. Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5569-74. doi: 10.1073/pnas.0701005104. Epub 2007 Mar 21. Proc Natl Acad Sci U S A. 2007. PMID: 17376864 Free PMC article.
A randomized, placebo-controlled phase 3 trial of the PI3Kδ inhibitor leniolisib for activated PI3Kδ syndrome.
Rao VK, Webster S, Šedivá A, Plebani A, Schuetz C, Shcherbina A, Conlon N, Coulter T, Dalm VA, Trizzino A, Zharankova Y, Kulm E, Körholz J, Lougaris V, Rodina Y, Radford K, Bradt J, Kucher K, Relan A, Holland SM, Lenardo MJ, Uzel G. Rao VK, et al. Blood. 2023 Mar 2;141(9):971-983. doi: 10.1182/blood.2022018546. Blood. 2023. PMID: 36399712 Free PMC article. Clinical Trial.
55,491 results
You have reached the last available page of results. Please see the User Guide for more information.