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Page 1
Mild cognitive impairment in Huntington's disease: challenges and outlooks.
Jellinger KA. Jellinger KA. J Neural Transm (Vienna). 2024 Apr;131(4):289-304. doi: 10.1007/s00702-024-02744-8. Epub 2024 Jan 24. J Neural Transm (Vienna). 2024. PMID: 38265518 Review.
Although Huntington's disease (HD) has classically been viewed as an autosomal-dominant inherited neurodegenerative motor disorder, cognitive and/or behavioral changes are predominant and often an early manifestation of disease. ...
Although Huntington's disease (HD) has classically been viewed as an autosomal-dominant inherited neurodegenerative motor disorder, c …
The pathobiology of depression in Huntington's disease: an unresolved puzzle.
Jellinger KA. Jellinger KA. J Neural Transm (Vienna). 2024 Dec;131(12):1511-1522. doi: 10.1007/s00702-024-02750-w. Epub 2024 Feb 13. J Neural Transm (Vienna). 2024. PMID: 38349403 Review.
Huntington's disease (HD) is an autosomal-dominant progressive neurodegenerative disease that manifests with a triad of symptoms including motor dysfunctions, cognitive deficits, and prominent neuropsychiatric symptoms, the most common of which is depression, with a preval …
Huntington's disease (HD) is an autosomal-dominant progressive neurodegenerative disease that manifests with a triad of symptoms incl …
Pathomechanisms of behavioral abnormalities in Huntington disease: an update.
Jellinger KA. Jellinger KA. J Neural Transm (Vienna). 2024 Sep;131(9):999-1012. doi: 10.1007/s00702-024-02794-y. Epub 2024 Jun 14. J Neural Transm (Vienna). 2024. PMID: 38874766 Review.
Huntington disease (HD), a devastating autosomal-dominant neurodegenerative disease caused by an expanded CAG trinucleotide repeat, is clinically characterized by a triad of symptoms including involuntary motions, behavior problems and cognitive deficits. ...
Huntington disease (HD), a devastating autosomal-dominant neurodegenerative disease caused by an expanded CAG trinucleotide repeat, i …
Consensus Statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the Management of Dyslipidemia and Prevention of Cardiovascular Disease Algorithm - 2020 Executive Summary.
Handelsman Y, Jellinger PS, Guerin CK, Bloomgarden ZT, Brinton EA, Budoff MJ, Davidson MH, Einhorn D, Fazio S, Fonseca VA, Garber AJ, Grunberger G, Krauss RM, Mechanick JI, Rosenblit PD, Smith DA, Wyne KL. Handelsman Y, et al. Endocr Pract. 2020 Oct;26(10):1196-1224. doi: 10.4158/CS-2020-0490. Endocr Pract. 2020. PMID: 33471721
Pallidal degenerations and related disorders: an update.
Jellinger KA. Jellinger KA. J Neural Transm (Vienna). 2022 Jun;129(5-6):521-543. doi: 10.1007/s00702-021-02392-2. Epub 2021 Aug 7. J Neural Transm (Vienna). 2022. PMID: 34363531 Review.
The differential diagnosis includes a large variety of neurodegenerations ranging from Huntington and Joseph-Machado disease, tauopathies (PSP), torsion dystonia, multiple system atrophy, neurodegeneration with brain iron accumulation (NBIA), and other extrapyramidal disor …
The differential diagnosis includes a large variety of neurodegenerations ranging from Huntington and Joseph-Machado disease, tauopat …
Alzheimer-type lesions in Huntington's disease.
Jellinger KA. Jellinger KA. J Neural Transm (Vienna). 1998;105(8-9):787-99. doi: 10.1007/s007020050095. J Neural Transm (Vienna). 1998. PMID: 9869319
Cognitive changes in Huntington's disease (HD) are variously related to diffuse cortical atrophy with neuron loss and dystrophic neurites leading to disruption of striato-frontal or limbic circuitries, while recent studies suggest an increasing prevalence of Alzheimer-like …
Cognitive changes in Huntington's disease (HD) are variously related to diffuse cortical atrophy with neuron loss and dystrophic neur …
Interaction between pathogenic proteins in neurodegenerative disorders.
Jellinger KA. Jellinger KA. J Cell Mol Med. 2012 Jun;16(6):1166-83. doi: 10.1111/j.1582-4934.2011.01507.x. J Cell Mol Med. 2012. PMID: 22176890 Free PMC article. Review.
Novel findings that have shifted our understanding in the role of pathologic proteins in the pathogenesis of Alzheimer, Parkinson, Huntington and prion diseases, have confirmed correlations/overlaps between these and other neurodegenerative disorders. ...
Novel findings that have shifted our understanding in the role of pathologic proteins in the pathogenesis of Alzheimer, Parkinson, Huntin …
Neuropathology and pathogenesis of extrapyramidal movement disorders: a critical update. II. Hyperkinetic disorders.
Jellinger KA. Jellinger KA. J Neural Transm (Vienna). 2019 Aug;126(8):997-1027. doi: 10.1007/s00702-019-02030-y. Epub 2019 Jun 24. J Neural Transm (Vienna). 2019. PMID: 31236685 Review.
Recent genetic and molecular classification distinguishes the following: (1) polyglutamine disorders (Huntington's disease and related disorders); (2) pantothenate kinase associated neurodegeneration; (3) Wilson's disease and related disorders; and (4) other hereditary neu …
Recent genetic and molecular classification distinguishes the following: (1) polyglutamine disorders (Huntington's disease and relate …
Cerebral correlates of psychotic syndromes in neurodegenerative diseases.
Jellinger KA. Jellinger KA. J Cell Mol Med. 2012 May;16(5):995-1012. doi: 10.1111/j.1582-4934.2011.01311.x. J Cell Mol Med. 2012. PMID: 21418522 Free PMC article. Review.
It includes hallucinations, delusions including paranoia, aggressive behaviour, apathy and other psychotic phenomena that occur in a wide range of degenerative disorders including Alzheimer's disease, synucleinopathies (Parkinson's disease, dementia with Lewy bodies), Huntingt …
It includes hallucinations, delusions including paranoia, aggressive behaviour, apathy and other psychotic phenomena that occur in a wide ra …
Activated immune system in patients with Huntington's disease.
Leblhuber F, Walli J, Jellinger K, Tilz GP, Widner B, Laccone F, Fuchs D. Leblhuber F, et al. Clin Chem Lab Med. 1998 Oct;36(10):747-50. doi: 10.1515/CCLM.1998.132. Clin Chem Lab Med. 1998. PMID: 9853799
Abnormalities of immune system compartments were determined in 12 patients with Huntington's disease (eight males, four females; age 42.4+/-11.7 years) and 11 controls (7 males, 4 females; age 47.0+/-12.0). ...The data indicate an activation of various immune system compar …
Abnormalities of immune system compartments were determined in 12 patients with Huntington's disease (eight males, four females; age …
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