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1989 2
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Page 1
Placebo effect characteristics observed in a single, international, longitudinal study in Huntington's disease.
Cubo E, González M, del Puerto I, de Yébenes JG, Arconada OF, Gabriel y Galán JM; European Huntington's Disease Initiative Study Group. Cubo E, et al. Mov Disord. 2012 Mar;27(3):439-42. doi: 10.1002/mds.24062. Epub 2011 Dec 9. Mov Disord. 2012. PMID: 22162184
BACKGROUND: Classically, clinical trials are based on the placebo-control design. Our aim was to analyze the placebo effect in Huntington's disease. METHODS: Placebo data were obtained from an international, longitudinal, placebo-controlled trial for Huntington's di …
BACKGROUND: Classically, clinical trials are based on the placebo-control design. Our aim was to analyze the placebo effect in Huntington
Activated immune system in patients with Huntington's disease.
Leblhuber F, Walli J, Jellinger K, Tilz GP, Widner B, Laccone F, Fuchs D. Leblhuber F, et al. Clin Chem Lab Med. 1998 Oct;36(10):747-50. doi: 10.1515/CCLM.1998.132. Clin Chem Lab Med. 1998. PMID: 9853799
Abnormalities of immune system compartments were determined in 12 patients with Huntington's disease (eight males, four females; age 42.4+/-11.7 years) and 11 controls (7 males, 4 females; age 47.0+/-12.0). ...The data indicate an activation of various immune system compar …
Abnormalities of immune system compartments were determined in 12 patients with Huntington's disease (eight males, four females; age …
Serum dehydroepiandrosterone and cortisol measurements in Huntington's chorea.
Leblhuber F, Peichl M, Neubauer C, Reisecker F, Steinparz FX, Windhager E, Maschek W. Leblhuber F, et al. J Neurol Sci. 1995 Sep;132(1):76-9. doi: 10.1016/0022-510x(95)00114-h. J Neurol Sci. 1995. PMID: 8523035 Clinical Trial.
Serum levels of dehydroepiandrosterone sulfate (DHEAS), known to antagonize metabolic effects of glucocorticoids in animals, and cortisol (CRT), already shown to be related to cognitive dysfunction in man and animals, were measured in 11 drug-free male subjects with definite H
Serum levels of dehydroepiandrosterone sulfate (DHEAS), known to antagonize metabolic effects of glucocorticoids in animals, and cortisol (C …
Weight loss in Huntington disease increases with higher CAG repeat number.
Aziz NA, van der Burg JM, Landwehrmeyer GB, Brundin P, Stijnen T; EHDI Study Group; Roos RA. Aziz NA, et al. Neurology. 2008 Nov 4;71(19):1506-13. doi: 10.1212/01.wnl.0000334276.09729.0e. Neurology. 2008. PMID: 18981372 Clinical Trial.
OBJECTIVE: Huntington disease (HD) is a hereditary neurodegenerative disorder caused by an expanded number of CAG repeats in the huntingtin gene. ...Similarly, R6/2 mice with a larger CAG repeat length had a lower body weight, whereas caloric intake increased with larger C …
OBJECTIVE: Huntington disease (HD) is a hereditary neurodegenerative disorder caused by an expanded number of CAG repeats in the hunt …
Degradation of tryptophan in neurodegenerative disorders.
Widner B, Leblhuber F, Walli J, Tilz GP, Demel U, Fuchs D. Widner B, et al. Adv Exp Med Biol. 1999;467:133-8. doi: 10.1007/978-1-4615-4709-9_19. Adv Exp Med Biol. 1999. PMID: 10721050
In patients with neurodegenerative disorders, namely Alzheimer's disease and Huntington's disease, we compared serum concentrations of tryptophan, kynurenine and the kynurenine per tryptophan ratio with concentrations of soluble immune activation markers. ...The data show …
In patients with neurodegenerative disorders, namely Alzheimer's disease and Huntington's disease, we compared serum concentrations o …
[Early and presymptomatic detection of Huntington chorea].
Leblhuber F. Leblhuber F. Fortschr Neurol Psychiatr. 1993 Jan;61(1):1-21. doi: 10.1055/s-2007-999115. Fortschr Neurol Psychiatr. 1993. PMID: 8440509 Review. German.
This review summarises the techniques for early and presymptomatic testing of Huntington's chorea, a chronic neurodegenerative disorder. Presenting electrodiagnostic, neuroradiographic and neuropsychological measurements, the problem of early detection of this hereditary d …
This review summarises the techniques for early and presymptomatic testing of Huntington's chorea, a chronic neurodegenerative disord …
Long latency EMG responses in early diagnosis of Huntington's chorea.
Leblhuber F, Windhager E, Reisecker F, Rittmannsberger H. Leblhuber F, et al. Eur Arch Psychiatry Clin Neurosci. 1991;241(2):113-4. doi: 10.1007/BF02191153. Eur Arch Psychiatry Clin Neurosci. 1991. PMID: 1834181
In healthy subjects, 2 EMG responses of the thenar muscles can be distinguished, elicited by electrical stimulation of the median nerve during an isometric contraction: an early spinal response (M1) and a long latency response (LLR) (M2); earlier studies have shown that in patien …
In healthy subjects, 2 EMG responses of the thenar muscles can be distinguished, elicited by electrical stimulation of the median nerve duri …
[Single-photon emission-computed tomography in the differential diagnosis of dementia].
Deisenhammer E, Reisecker F, Leblhuber F, Höll K, Markut H, Trenkler J, Schneider I. Deisenhammer E, et al. Dtsch Med Wochenschr. 1989 Oct 27;114(43):1639-44. doi: 10.1055/s-2008-1066808. Dtsch Med Wochenschr. 1989. PMID: 2530079 German.
Both patients with dementia of Pick type had definite decreases in frontal perfusion. All 21 patients with dementia due to Huntington's chorea showed a typical pattern with absent perfusion of the head of the caudate nucleus, although in three of them conventional computed …
Both patients with dementia of Pick type had definite decreases in frontal perfusion. All 21 patients with dementia due to Huntington
11 results