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Year Number of Results
2000 1
2011 13
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8,717 results

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Page 1
LNCcation: lncRNA localization and function.
Bridges MC, Daulagala AC, Kourtidis A. Bridges MC, et al. J Cell Biol. 2021 Feb 1;220(2):e202009045. doi: 10.1083/jcb.202009045. J Cell Biol. 2021. PMID: 33464299 Free PMC article. Review.
This is also evident for the large and relatively novel class of long noncoding RNAs (lncRNAs). Because lncRNAs are defined as RNA transcripts >200 nucleotides that do not encode protein, they are themselves the functional units, making their …
This is also evident for the large and relatively novel class of long noncoding RNAs (lncRNAs). Because lncRNAs …
Integrated lncRNA function upon genomic and epigenomic regulation.
Herman AB, Tsitsipatis D, Gorospe M. Herman AB, et al. Mol Cell. 2022 Jun 16;82(12):2252-2266. doi: 10.1016/j.molcel.2022.05.027. Mol Cell. 2022. PMID: 35714586 Free PMC article. Review.
Although some long noncoding (lnc)RNAs are known since the 1950s, the past 25 years have uncovered myriad lncRNAs with diverse sequences, structures, and functions. The advent of high-throughput and sensitive technologies has further uncovered the vast hetero …
Although some long noncoding (lnc)RNAs are known since the 1950s, the past 25 years have uncovered myriad lncRNAs with …
Functional Classification and Experimental Dissection of Long Noncoding RNAs.
Kopp F, Mendell JT. Kopp F, et al. Cell. 2018 Jan 25;172(3):393-407. doi: 10.1016/j.cell.2018.01.011. Cell. 2018. PMID: 29373828 Free PMC article. Review.
Over the last decade, it has been increasingly demonstrated that the genomes of many species are pervasively transcribed, resulting in the production of numerous long noncoding RNAs (lncRNAs). At the same time, it is now appreciated that many types of DNA reg …
Over the last decade, it has been increasingly demonstrated that the genomes of many species are pervasively transcribed, resulting in the p …
LncRNA-mediated posttranslational modifications and reprogramming of energy metabolism in cancer.
Tan YT, Lin JF, Li T, Li JJ, Xu RH, Ju HQ. Tan YT, et al. Cancer Commun (Lond). 2021 Feb;41(2):109-120. doi: 10.1002/cac2.12108. Epub 2020 Oct 29. Cancer Commun (Lond). 2021. PMID: 33119215 Free PMC article. Review.
Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism has historically been considered a general phenomenon of tumors. It is well recognized that long noncoding RNAs (lncRNAs) regulate energy metabolism in cancer. However, …
Altered metabolism is a hallmark of cancer, and the reprogramming of energy metabolism has historically been considered a general phenomenon …
Long Noncoding RNA and Cancer: A New Paradigm.
Bhan A, Soleimani M, Mandal SS. Bhan A, et al. Cancer Res. 2017 Aug 1;77(15):3965-3981. doi: 10.1158/0008-5472.CAN-16-2634. Epub 2017 Jul 12. Cancer Res. 2017. PMID: 28701486 Free PMC article. Review.
In addition to mutations or aberrant expression in the protein-coding genes, mutations and misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to play major roles in cancer. Genome-wide association studies of tumor sampl …
In addition to mutations or aberrant expression in the protein-coding genes, mutations and misregulation of noncoding RNAs, in partic …
Revealing protein-lncRNA interaction.
Ferrè F, Colantoni A, Helmer-Citterich M. Ferrè F, et al. Brief Bioinform. 2016 Jan;17(1):106-16. doi: 10.1093/bib/bbv031. Epub 2015 Jun 2. Brief Bioinform. 2016. PMID: 26041786 Free PMC article. Review.
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs are often able to bind a large number of different RNAs. ...Several differen …
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of which require the interaction with …
Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics.
Nojima T, Proudfoot NJ. Nojima T, et al. Nat Rev Mol Cell Biol. 2022 Jun;23(6):389-406. doi: 10.1038/s41580-021-00447-6. Epub 2022 Jan 25. Nat Rev Mol Cell Biol. 2022. PMID: 35079163 Review.
Mammalian genomes express two principal gene categories through RNA polymerase II-mediated transcription: protein-coding transcription units and non-coding RNA transcription units. Non-coding RNAs are further divided into relatively abundant structural RNAs, such as …
Mammalian genomes express two principal gene categories through RNA polymerase II-mediated transcription: protein-coding transcriptio …
On the classification of long non-coding RNAs.
Ma L, Bajic VB, Zhang Z. Ma L, et al. RNA Biol. 2013 Jun;10(6):925-33. doi: 10.4161/rna.24604. Epub 2013 Apr 15. RNA Biol. 2013. PMID: 23696037 Free PMC article. Review.
Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide variety of important biological processes. ...We believe that the classifications of lncRNAs as indicated above are of fundamental importance for lncRNA studies, help …
Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide variety of important biological processe …
Tumor immune microenvironment lncRNAs.
Park EG, Pyo SJ, Cui Y, Yoon SH, Nam JW. Park EG, et al. Brief Bioinform. 2022 Jan 17;23(1):bbab504. doi: 10.1093/bib/bbab504. Brief Bioinform. 2022. PMID: 34891154 Free PMC article. Review.
Long non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their cell type-specific gene expression and other functional evidence support the idea that lncRNAs have distinct cellular functions in th …
Long non-coding ribonucleic acids (RNAs) (lncRNAs) are key players in tumorigenesis and immune responses. The nature of their …
The Pathogenesis of Diabetes.
Guo H, Wu H, Li Z. Guo H, et al. Int J Mol Sci. 2023 Apr 10;24(8):6978. doi: 10.3390/ijms24086978. Int J Mol Sci. 2023. PMID: 37108143 Free PMC article. Review.
This review provides the current global state of diabetes, the mechanisms involved in glucose homeostasis and diabetic insulin resistance, and the long-chain non-coding RNA (lncRNA) associated with diabetes....
This review provides the current global state of diabetes, the mechanisms involved in glucose homeostasis and diabetic insulin resistance, a …
8,717 results