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CITED2 Cooperates with ISL1 and Promotes Cardiac Differentiation of Mouse Embryonic Stem Cells.
Pacheco-Leyva I, Matias AC, Oliveira DV, Santos JM, Nascimento R, Guerreiro E, Michell AC, van De Vrugt AM, Machado-Oliveira G, Ferreira G, Domian I, Bragança J. Pacheco-Leyva I, et al. Among authors: braganca j. Stem Cell Reports. 2016 Dec 13;7(6):1037-1049. doi: 10.1016/j.stemcr.2016.10.002. Epub 2016 Nov 3. Stem Cell Reports. 2016. PMID: 27818139 Free PMC article.
The transcriptional regulator CITED2 is essential for heart development. Here, we investigated the role of CITED2 in the specification of cardiac cell fate from mouse embryonic stem cells (ESC). ...Conversely, the depletion of Cited2
The transcriptional regulator CITED2 is essential for heart development. Here, we investigated the role of CITED2 in th …
Ectopic expression of CITED2 prior to reprogramming, promotes and homogenises the conversion of somatic cells into induced pluripotent stem cells.
Charneca J, Matias AC, Escapa AL, Fernandes C, Alves A, Santos JMA, Nascimento R, Bragança J. Charneca J, et al. Among authors: braganca j. Exp Cell Res. 2017 Sep 15;358(2):290-300. doi: 10.1016/j.yexcr.2017.07.002. Epub 2017 Jul 3. Exp Cell Res. 2017. PMID: 28684114
Cited2 plays crucial roles in mouse embryonic stem cells self-renewal, the initiation of the somatic reprogramming process into induced pluripotent stem cells (iPSC) and the suppression of cell senescence. ...The ectopic CITED2 exp
Cited2 plays crucial roles in mouse embryonic stem cells self-renewal, the initiation of the somatic reprogramming proc