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Page 1
International Clinical Practice Guidelines for Sarcopenia (ICFSR): Screening, Diagnosis and Management.
Dent E, Morley JE, Cruz-Jentoft AJ, Arai H, Kritchevsky SB, Guralnik J, Bauer JM, Pahor M, Clark BC, Cesari M, Ruiz J, Sieber CC, Aubertin-Leheudre M, Waters DL, Visvanathan R, Landi F, Villareal DT, Fielding R, Won CW, Theou O, Martin FC, Dong B, Woo J, Flicker L, Ferrucci L, Merchant RA, Cao L, Cederholm T, Ribeiro SML, Rodríguez-Mañas L, Anker SD, Lundy J, Gutiérrez Robledo LM, Bautmans I, Aprahamian I, Schols JMGA, Izquierdo M, Vellas B. Dent E, et al. Among authors: cesari m. J Nutr Health Aging. 2018;22(10):1148-1161. doi: 10.1007/s12603-018-1139-9. J Nutr Health Aging. 2018. PMID: 30498820 Free PMC article.
OBJECTIVES: Sarcopenia, defined as an age-associated loss of skeletal muscle function and muscle mass, occurs in approximately 6 - 22 % of older adults. This paper presents evidence-based clinical practice guidelines for screening, diagnosis and management of sarcop …
OBJECTIVES: Sarcopenia, defined as an age-associated loss of skeletal muscle function and muscle mass, occurs in approximately 6 - 22 % of o …
Delirium and frailty in older adults: Clinical overlap and biological underpinnings.
Bellelli G, Triolo F, Ferrara MC, Deiner SG, Morandi A, Cesari M, Davis D, Marengoni A, Inzitari M, Watne LO, Rockwood K, Vetrano DL. Bellelli G, et al. Among authors: cesari m. J Intern Med. 2024 Nov;296(5):382-398. doi: 10.1111/joim.20014. Epub 2024 Oct 1. J Intern Med. 2024. PMID: 39352688 Free article. Review.
Frailty and delirium are two common geriatric syndromes sharing several clinical characteristics, risk factors, and negative outcomes. ...The proposed unifying framework supports the integration and measurement of both constructs in research and clinical p …
Frailty and delirium are two common geriatric syndromes sharing several clinical characteristics, risk factors, and negative o …
Global consensus on optimal exercise recommendations for enhancing healthy longevity in older adults (ICFSR).
Izquierdo M, de Souto Barreto P, Arai H, Bischoff-Ferrari HA, Cadore EL, Cesari M, Chen LK, Coen PM, Courneya KS, Duque G, Ferrucci L, Fielding RA, García-Hermoso A, Gutiérrez-Robledo LM, Harridge SDR, Kirk B, Kritchevsky S, Landi F, Lazarus N, Liu-Ambrose T, Marzetti E, Merchant RA, Morley JE, Pitkälä KH, Ramírez-Vélez R, Rodriguez-Mañas L, Rolland Y, Ruiz JG, Sáez de Asteasu ML, Villareal DT, Waters DL, Won Won C, Vellas B, Fiatarone Singh MA. Izquierdo M, et al. Among authors: cesari m. J Nutr Health Aging. 2025 Jan;29(1):100401. doi: 10.1016/j.jnha.2024.100401. Epub 2025 Jan 1. J Nutr Health Aging. 2025. PMID: 39743381 Free PMC article. Review.
Particularly important are anabolic exercises, such as Progressive resistance training (PRT), which are indispensable for maintaining or improving functional capacity in older adults, particularly those with frailty, sarcopenia or osteoporosis, or those hospitalized or in …
Particularly important are anabolic exercises, such as Progressive resistance training (PRT), which are indispensable for maintaining or imp …
The Asia-Pacific Clinical Practice Guidelines for the Management of Frailty.
Dent E, Lien C, Lim WS, Wong WC, Wong CH, Ng TP, Woo J, Dong B, de la Vega S, Hua Poi PJ, Kamaruzzaman SBB, Won C, Chen LK, Rockwood K, Arai H, Rodriguez-Mañas L, Cao L, Cesari M, Chan P, Leung E, Landi F, Fried LP, Morley JE, Vellas B, Flicker L. Dent E, et al. Among authors: cesari m. J Am Med Dir Assoc. 2017 Jul 1;18(7):564-575. doi: 10.1016/j.jamda.2017.04.018. J Am Med Dir Assoc. 2017. PMID: 28648901
OBJECTIVE: To develop Clinical Practice Guidelines for the screening, assessment and management of the geriatric condition of frailty. ...This process involved detailed evaluation of the current scientific evidence paired with expert panel interpretation. Thr …
OBJECTIVE: To develop Clinical Practice Guidelines for the screening, assessment and management of the geriatric condition of …
Sarcopenia in daily practice: assessment and management.
Beaudart C, McCloskey E, Bruyère O, Cesari M, Rolland Y, Rizzoli R, Araujo de Carvalho I, Amuthavalli Thiyagarajan J, Bautmans I, Bertière MC, Brandi ML, Al-Daghri NM, Burlet N, Cavalier E, Cerreta F, Cherubini A, Fielding R, Gielen E, Landi F, Petermans J, Reginster JY, Visser M, Kanis J, Cooper C. Beaudart C, et al. Among authors: cesari m. BMC Geriatr. 2016 Oct 5;16(1):170. doi: 10.1186/s12877-016-0349-4. BMC Geriatr. 2016. PMID: 27716195 Free PMC article. Review.
BACKGROUND: Sarcopenia is increasingly recognized as a correlate of ageing and is associated with increased likelihood of adverse outcomes including falls, fractures, frailty and mortality. Several tools have been recommended to assess muscle mass, muscle strength and phys …
BACKGROUND: Sarcopenia is increasingly recognized as a correlate of ageing and is associated with increased likelihood of adverse outcomes i …
Assessment of Muscle Function and Physical Performance in Daily Clinical Practice : A position paper endorsed by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO).
Beaudart C, Rolland Y, Cruz-Jentoft AJ, Bauer JM, Sieber C, Cooper C, Al-Daghri N, Araujo de Carvalho I, Bautmans I, Bernabei R, Bruyère O, Cesari M, Cherubini A, Dawson-Hughes B, Kanis JA, Kaufman JM, Landi F, Maggi S, McCloskey E, Petermans J, Rodriguez Mañas L, Reginster JY, Roller-Wirnsberger R, Schaap LA, Uebelhart D, Rizzoli R, Fielding RA. Beaudart C, et al. Among authors: cesari m. Calcif Tissue Int. 2019 Jul;105(1):1-14. doi: 10.1007/s00223-019-00545-w. Epub 2019 Apr 10. Calcif Tissue Int. 2019. PMID: 30972475 Free article. Review.
In this paper, an overview of different methods available and applicable in clinical settings is proposed. This paper is based on literature reviews performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ES …
In this paper, an overview of different methods available and applicable in clinical settings is proposed. This paper is based on lit …
The frailty phenotype and the frailty index: different instruments for different purposes.
Cesari M, Gambassi G, van Kan GA, Vellas B. Cesari M, et al. Age Ageing. 2014 Jan;43(1):10-2. doi: 10.1093/ageing/aft160. Epub 2013 Oct 16. Age Ageing. 2014. PMID: 24132852
The integration of frailty measures in clinical practice is crucial for the development of interventions against disabling conditions in older persons. The frailty phenotype (proposed and validated by Fried and colleagues in the Cardiovascular Health S …
The integration of frailty measures in clinical practice is crucial for the development of interventions against disabl …
Evidence for the Domains Supporting the Construct of Intrinsic Capacity.
Cesari M, Araujo de Carvalho I, Amuthavalli Thiyagarajan J, Cooper C, Martin FC, Reginster JY, Vellas B, Beard JR. Cesari M, et al. J Gerontol A Biol Sci Med Sci. 2018 Nov 10;73(12):1653-1660. doi: 10.1093/gerona/gly011. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29408961 Review.
This innovative model recently proposed by the World Health Organization has the potential to substantially modify the way in which clinical practice is currently conducted, shifting from disease-centered toward function-centered paradigms. ...In order to facilitate …
This innovative model recently proposed by the World Health Organization has the potential to substantially modify the way in which clini …
Frailty in Clinical Practice.
Cesari M, Vellas B. Cesari M, et al. Nestle Nutr Inst Workshop Ser. 2015;83:93-8. doi: 10.1159/000382091. Epub 2015 Oct 20. Nestle Nutr Inst Workshop Ser. 2015. PMID: 26485035 Review.
From a theoretical viewpoint, the concept of frailty has been well established, but its operationalization is still subject to controversy. This impediment leads to the postponement of the integration of frailty in the clinical setting. In the present article …
From a theoretical viewpoint, the concept of frailty has been well established, but its operationalization is still subject to contro …
Evidence supporting the best clinical management of patients with multimorbidity and polypharmacy: a systematic guideline review and expert consensus.
Muth C, Blom JW, Smith SM, Johnell K, Gonzalez-Gonzalez AI, Nguyen TS, Brueckle MS, Cesari M, Tinetti ME, Valderas JM. Muth C, et al. Among authors: cesari m. J Intern Med. 2019 Mar;285(3):272-288. doi: 10.1111/joim.12842. Epub 2018 Dec 10. J Intern Med. 2019. PMID: 30357955 Free article.
The complexity and heterogeneity of patients with multimorbidity and polypharmacy renders traditional disease-oriented guidelines often inadequate and complicates clinical decision making. To address this challenge, guidelines have been developed on multimorbidity or polyp …
The complexity and heterogeneity of patients with multimorbidity and polypharmacy renders traditional disease-oriented guidelines often inad …
44 results