Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 2
1999 1
2000 3
2001 1
2002 3
2003 1
2005 5
2006 1
2007 3
2008 1
2009 3
2010 3
2011 2
2012 1
2013 5
2014 3
2015 4
2016 3
2017 5
2018 3
2019 6
2020 2
2021 4
2022 2
2023 2
2024 2
2025 3
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

69 results

Results by year

Filters applied: . Clear all
Page 1
Mitochondria as Signaling Organelles Control Mammalian Stem Cell Fate.
Chakrabarty RP, Chandel NS. Chakrabarty RP, et al. Among authors: chandel ns. Cell Stem Cell. 2021 Mar 4;28(3):394-408. doi: 10.1016/j.stem.2021.02.011. Cell Stem Cell. 2021. PMID: 33667360 Free PMC article. Review.
However, it is now clear that beyond these canonical roles, mitochondria as signaling organelles dictate stem cell fate and function. In this review, we focus on key conceptual ideas on how mitochondria control mammalian stem cell fate and function thr …
However, it is now clear that beyond these canonical roles, mitochondria as signaling organelles dictate stem cell fate …
Mitochondrial TCA cycle metabolites control physiology and disease.
Martínez-Reyes I, Chandel NS. Martínez-Reyes I, et al. Among authors: chandel ns. Nat Commun. 2020 Jan 3;11(1):102. doi: 10.1038/s41467-019-13668-3. Nat Commun. 2020. PMID: 31900386 Free PMC article. Review.
Mitochondria are signaling organelles that regulate a wide variety of cellular functions and can dictate cell fate. ...We will focus on how these metabolites mediated signaling can affect physiology and disease....
Mitochondria are signaling organelles that regulate a wide variety of cellular functions and can dictate cell fate. ... …
Fundamentals of cancer metabolism.
DeBerardinis RJ, Chandel NS. DeBerardinis RJ, et al. Among authors: chandel ns. Sci Adv. 2016 May 27;2(5):e1600200. doi: 10.1126/sciadv.1600200. eCollection 2016 May. Sci Adv. 2016. PMID: 27386546 Free PMC article. Review.
Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.
Lee P, Chandel NS, Simon MC. Lee P, et al. Among authors: chandel ns. Nat Rev Mol Cell Biol. 2020 May;21(5):268-283. doi: 10.1038/s41580-020-0227-y. Epub 2020 Mar 6. Nat Rev Mol Cell Biol. 2020. PMID: 32144406 Free PMC article. Review.
Importantly, changes in oxygen can also be sensed via other stress pathways as well as changes in metabolite levels and the generation of reactive oxygen species by mitochondria. Collectively, this leads to cellular adaptations of protein synthesis, energy metabolism, mito …
Importantly, changes in oxygen can also be sensed via other stress pathways as well as changes in metabolite levels and the generation of re …
Lipid Metabolism.
Chandel NS. Chandel NS. Cold Spring Harb Perspect Biol. 2021 Sep 1;13(9):a040576. doi: 10.1101/cshperspect.a040576. Cold Spring Harb Perspect Biol. 2021. PMID: 34470787 Free PMC article. Review. No abstract available.
Mitochondria as signaling organelles.
Chandel NS. Chandel NS. BMC Biol. 2014 May 27;12:34. doi: 10.1186/1741-7007-12-34. BMC Biol. 2014. PMID: 24884669 Free PMC article. Review.
Almost 20 years ago, the discovery that mitochondrial release of cytochrome c initiates a cascade that leads to cell death brought about a wholesale change in how cell biologists think of mitochondria. Formerly viewed as sites of biosynthesis and bioenergy production, thes …
Almost 20 years ago, the discovery that mitochondrial release of cytochrome c initiates a cascade that leads to cell death brought about a w …
ROS-dependent signal transduction.
Reczek CR, Chandel NS. Reczek CR, et al. Among authors: chandel ns. Curr Opin Cell Biol. 2015 Apr;33:8-13. doi: 10.1016/j.ceb.2014.09.010. Epub 2014 Oct 8. Curr Opin Cell Biol. 2015. PMID: 25305438 Free PMC article. Review.
Although redox-dependent signaling has been implicated in numerous cellular processes, the mechanism by which the ROS signal is transmitted to its target protein in the face of highly reactive and abundant antioxidants is not fully understood. In this review of redo …
Although redox-dependent signaling has been implicated in numerous cellular processes, the mechanism by which the ROS signal i …
Mitochondria reactive oxygen species signaling-dependent immune responses in macrophages and T cells.
Weinberg SE, Chandel NS. Weinberg SE, et al. Among authors: chandel ns. Immunity. 2025 Aug 12;58(8):1904-1921. doi: 10.1016/j.immuni.2025.07.012. Epub 2025 Aug 4. Immunity. 2025. PMID: 40763730 Free article. Review.
Mitochondria are key regulators of immune cell function, going beyond their traditional role in ATP and metabolite production to support anabolic processes and act as hubs for intracellular signaling. A key aspect of this signaling function is the production …
Mitochondria are key regulators of immune cell function, going beyond their traditional role in ATP and metabolite production to supp …
SnapShot: Mitochondrial signaling.
Poor TA, Chandel NS. Poor TA, et al. Among authors: chandel ns. Mol Cell. 2023 Mar 16;83(6):1012-1012.e1. doi: 10.1016/j.molcel.2023.01.008. Mol Cell. 2023. PMID: 36931250 Free article.
Mitochondria have emerged as signaling organelles with roles beyond their well-established function in generating ATP and metabolites for macromolecule synthesis. Healthy mitochondria integrate various physiologic inputs and communicate signals …
Mitochondria have emerged as signaling organelles with roles beyond their well-established function in generating ATP a …
Evolution of Mitochondria as Signaling Organelles.
Chandel NS. Chandel NS. Cell Metab. 2015 Aug 4;22(2):204-6. doi: 10.1016/j.cmet.2015.05.013. Epub 2015 Jun 11. Cell Metab. 2015. PMID: 26073494 Free article. Review.
Mitochondria have primarily been viewed as bioenergetic and biosynthetic organelles that autonomously co-exist within the cell. However, the past two decades have provided evidence that mitochondria function as signaling organelles, constantly c …
Mitochondria have primarily been viewed as bioenergetic and biosynthetic organelles that autonomously co-exist within the cell …
69 results