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2011 1
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An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, Nagy A, Wrana JL, Blencowe BJ. Gabut M, et al. Cell. 2011 Sep 30;147(1):132-46. doi: 10.1016/j.cell.2011.08.023. Epub 2011 Sep 15. Cell. 2011. PMID: 21924763 Free article.
Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene expression. ...This isoform also promotes the maintenance of ESC pluripotency and contributes to efficient reprogramming of som
Alternative splicing (AS) is a key process underlying the expansion of proteomic diversity and the regulation of gene e
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.
Han H, Irimia M, Ross PJ, Sung HK, Alipanahi B, David L, Golipour A, Gabut M, Michael IP, Nachman EN, Wang E, Trcka D, Thompson T, O'Hanlon D, Slobodeniuc V, Barbosa-Morais NL, Burge CB, Moffat J, Frey BJ, Nagy A, Ellis J, Wrana JL, Blencowe BJ. Han H, et al. Among authors: gabut m. Nature. 2013 Jun 13;498(7453):241-5. doi: 10.1038/nature12270. Epub 2013 Jun 5. Nature. 2013. PMID: 23739326 Free PMC article.
Alternative splicing represents a widely acting mode of gene regulation, yet its role in regulating ES-cell pluripotency and differentiation is poorly understood. ...Among the MBNL-regulated events is an ES-cell-specific
Alternative splicing represents a widely acting mode of gene regulation, yet its role in regulating ES-cell