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Novel nano-composite multilayered biomaterial for osteochondral regeneration: a pilot clinical trial.
Kon E, Delcogliano M, Filardo G, Busacca M, Di Martino A, Marcacci M. Kon E, et al. Am J Sports Med. 2011 Jun;39(6):1180-90. doi: 10.1177/0363546510392711. Epub 2011 Feb 10. Am J Sports Med. 2011. PMID: 21310939 Clinical Trial.
STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A multilayer gradient nano-composite scaffold was obtained by nucleating collagen type I fibrils with hydroxyapatite nanoparticles. ...CONCLUSION: This open 1-step procedure was used for the treatment …
STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A multilayer gradient nano-composite scaffold was obtained by …
A novel nano-composite multi-layered biomaterial for treatment of osteochondral lesions: technique note and an early stability pilot clinical trial.
Kon E, Delcogliano M, Filardo G, Pressato D, Busacca M, Grigolo B, Desando G, Marcacci M. Kon E, et al. Injury. 2010 Jul;41(7):693-701. doi: 10.1016/j.injury.2009.11.014. Epub 2009 Dec 24. Injury. 2010. PMID: 20035935 Clinical Trial.
The objective of this pilot clinical study is to evaluate the performance and the intrinsic stability of a newly developed biomimetic osteochondral scaffold and to test the safety and the feasibility of the surgical procedure. ...CONCLUSIONS: The technique is …
The objective of this pilot clinical study is to evaluate the performance and the intrinsic stability of a newly developed bio …