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Tissue engineering strategies for the regeneration of orthopedic interfaces.
Lu HH, Subramony SD, Boushell MK, Zhang X. Lu HH, et al. Ann Biomed Eng. 2010 Jun;38(6):2142-54. doi: 10.1007/s10439-010-0046-y. Epub 2010 Apr 27. Ann Biomed Eng. 2010. PMID: 20422291 Free PMC article. Review.
A major focus in the field of orthopedic tissue engineering is the development of tissue engineered bone and soft tissue grafts with biomimetic functionality to allow for their translation to the clinical setting. ...This review discusses tis
A major focus in the field of orthopedic tissue engineering is the development of tissue engineered bone and sof …
Orthopedic interface tissue engineering for the biological fixation of soft tissue grafts.
Moffat KL, Wang IN, Rodeo SA, Lu HH. Moffat KL, et al. Among authors: lu hh. Clin Sports Med. 2009 Jan;28(1):157-76. doi: 10.1016/j.csm.2008.08.006. Clin Sports Med. 2009. PMID: 19064172 Free PMC article. Review.
Interface tissue engineering is a promising new strategy aimed at the regeneration of tissue interfaces and ultimately enabling the biological fixation of soft tissue grafts used in orthopedic repair and sports medici
Interface tissue engineering is a promising new strategy aimed at the regeneration of tissue in
Integrating soft and hard tissues via interface tissue engineering.
Patel S, Caldwell JM, Doty SB, Levine WN, Rodeo S, Soslowsky LJ, Thomopoulos S, Lu HH. Patel S, et al. Among authors: lu hh. J Orthop Res. 2018 Apr;36(4):1069-1077. doi: 10.1002/jor.23810. Epub 2018 Jan 5. J Orthop Res. 2018. PMID: 29149506 Free PMC article. Review.
Interface tissue engineering represents an integrative strategy for regenerating the native enthesis by functionally connecting soft and hard tissues and thereby improving clinical outcome. ...These innovative studies underscore the clinical rel
Interface tissue engineering represents an integrative strategy for regenerating the native enthesis by f
Current strategies for integrative cartilage repair.
Boushell MK, Hung CT, Hunziker EB, Strauss EJ, Lu HH. Boushell MK, et al. Among authors: lu hh. Connect Tissue Res. 2017 Sep;58(5):393-406. doi: 10.1080/03008207.2016.1231180. Epub 2016 Sep 6. Connect Tissue Res. 2017. PMID: 27599801 Review.
Similarly, tissue-engineered grafts that facilitate cartilage and bone regeneration are challenged by how to integrate the graft seamlessly with surrounding host cartilage and/or bone. ...Moreover, models that accurately evaluate the ability of cartilage grafts to e …
Similarly, tissue-engineered grafts that facilitate cartilage and bone regeneration are challenged by how to integrate the gra …
Multilayer scaffolds in orthopaedic tissue engineering.
Atesok K, Doral MN, Karlsson J, Egol KA, Jazrawi LM, Coelho PG, Martinez A, Matsumoto T, Owens BD, Ochi M, Hurwitz SR, Atala A, Fu FH, Lu HH, Rodeo SA. Atesok K, et al. Among authors: lu hh. Knee Surg Sports Traumatol Arthrosc. 2016 Jul;24(7):2365-73. doi: 10.1007/s00167-014-3453-z. Epub 2014 Dec 3. Knee Surg Sports Traumatol Arthrosc. 2016. PMID: 25466277 Review.
Studies were divided into three main categories based on tissue types and interfaces for which multilayer scaffolds were used to regenerate: bone, osteochondral junction and tendon-to-bone interfaces. ...This emerging tissue engineering a …
Studies were divided into three main categories based on tissue types and interfaces for which multilayer scaffolds were used …
Engineering complex orthopaedic tissues via strategic biomimicry.
Qu D, Mosher CZ, Boushell MK, Lu HH. Qu D, et al. Among authors: lu hh. Ann Biomed Eng. 2015 Mar;43(3):697-717. doi: 10.1007/s10439-014-1190-6. Epub 2014 Dec 3. Ann Biomed Eng. 2015. PMID: 25465616 Free PMC article. Review.
Closely related is the effort to re-establish tissue-tissue interfaces, which is essential for joining these tissue building blocks and facilitating host integration. ...Application of this engineering strategy for the regeneration
Closely related is the effort to re-establish tissue-tissue interfaces, which is essential for joining these tissue
Stratified scaffold design for engineering composite tissues.
Mosher CZ, Spalazzi JP, Lu HH. Mosher CZ, et al. Among authors: lu hh. Methods. 2015 Aug;84:99-102. doi: 10.1016/j.ymeth.2015.03.029. Epub 2015 Apr 3. Methods. 2015. PMID: 25846397
To enable integration, a stratified scaffold design that mimics the multiple tissue regions of the ACL interface (ligament-fibrocartilage-bone) represents a promising strategy for composite tissue formation. ...The primary advantage of the tri-phasic s …
To enable integration, a stratified scaffold design that mimics the multiple tissue regions of the ACL interface (ligament-fib …