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Intracellular antioxidant enzymes are not globally upregulated during hibernation in the major oxidative tissues of the 13-lined ground squirrel Spermophilus tridecemlineatus.
Page MM, Peters CW, Staples JF, Stuart JA. Page MM, et al. Comp Biochem Physiol A Mol Integr Physiol. 2009 Jan;152(1):115-22. doi: 10.1016/j.cbpa.2008.09.032. Epub 2008 Oct 9. Comp Biochem Physiol A Mol Integr Physiol. 2009. PMID: 18948223
In many animals, cellular oxidative stress resistance is associated with enhanced expression of intracellular antioxidant enzymes. Intracellular antioxidant capacity may be upregulated during hibernation to protect against oxidative damage associated with the …
In many animals, cellular oxidative stress resistance is associated with enhanced expression of intracellular antioxidant enzymes
Upregulation of intracellular antioxidant enzymes in brain and heart during estivation in the African lungfish Protopterus dolloi.
Page MM, Salway KD, Ip YK, Chew SF, Warren SA, Ballantyne JS, Stuart JA. Page MM, et al. J Comp Physiol B. 2010 Mar;180(3):361-9. doi: 10.1007/s00360-009-0416-7. Epub 2009 Nov 4. J Comp Physiol B. 2010. PMID: 19888582
Estivation is similar to the diapause and hibernation of other animal species in that it is characterized by negligible activity and a profoundly depressed metabolic rate. ...We tested the hypothesis that P. dolloi enhances stress resistance during estivation by upr …
Estivation is similar to the diapause and hibernation of other animal species in that it is characterized by negligible activity
Mechanisms of stress resistance in Snell dwarf mouse fibroblasts: enhanced antioxidant and DNA base excision repair capacity, but no differences in mitochondrial metabolism.
Page MM, Salmon AB, Leiser SF, Robb EL, Brown MF, Miller RA, Stuart JA. Page MM, et al. Free Radic Biol Med. 2009 Apr 15;46(8):1109-18. doi: 10.1016/j.freeradbiomed.2009.01.014. Epub 2009 Jan 23. Free Radic Biol Med. 2009. PMID: 19439226 Free PMC article.
Dermal fibroblasts from long-lived Snell dwarf mice can withstand a variety of oxidative and non-oxidative stressors compared to normal littermate controls. Here, we report differences in the levels and activities of intracellular antioxidant and DNA repair enzym
Dermal fibroblasts from long-lived Snell dwarf mice can withstand a variety of oxidative and non-oxidative stressors compared to normal litt …
Molecular mechanisms of oxidative stress resistance induced by resveratrol: Specific and progressive induction of MnSOD.
Robb EL, Page MM, Wiens BE, Stuart JA. Robb EL, et al. Among authors: page mm. Biochem Biophys Res Commun. 2008 Mar 7;367(2):406-12. doi: 10.1016/j.bbrc.2007.12.138. Epub 2007 Dec 31. Biochem Biophys Res Commun. 2008. PMID: 18167310
Here, we report the effects of long-term exposure to micromolar concentrations of RES on antioxidant and DNA repair enzyme activities in a human cell line (MRC-5). ...However, it dramatically and progressively induced mitochondrial MnSOD expression and act
Here, we report the effects of long-term exposure to micromolar concentrations of RES on antioxidant and DNA repair enzyme