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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1982 2
1983 3
1984 1
1985 2
1986 8
1987 7
1988 4
1989 4
1990 5
1991 6
1992 1
1993 3
1994 3
1995 5
1996 3
1997 7
1998 3
1999 4
2000 3
2001 2
2002 3
2003 2
2004 2
2005 4
2006 2
2007 1
2008 4
2009 3
2010 4
2011 5
2012 4
2013 5
2014 3
2015 3
2016 2
2017 6
2019 1
2021 0
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125 results
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Page 1
Differentiation of effector CD4 T cell populations (*).
Zhu J, Yamane H, Paul WE. Zhu J, et al. Among authors: paul we. Annu Rev Immunol. 2010;28:445-89. doi: 10.1146/annurev-immunol-030409-101212. Annu Rev Immunol. 2010. PMID: 20192806 Free PMC article. Review.
They are also involved in autoimmunity, asthma, and allergic responses as well as in tumor immunity. During TCR activation in a particular cytokine milieu, naive CD4 T cells may differentiate into one of several lineages of T helper (Th) cells, including Th1, Th2, T …
They are also involved in autoimmunity, asthma, and allergic responses as well as in tumor immunity. During TCR activation in a parti …
Lymphocyte responses and cytokines.
Paul WE, Seder RA. Paul WE, et al. Cell. 1994 Jan 28;76(2):241-51. doi: 10.1016/0092-8674(94)90332-8. Cell. 1994. PMID: 7904900 Review. No abstract available.
IL-25-responsive, lineage-negative KLRG1(hi) cells are multipotential 'inflammatory' type 2 innate lymphoid cells.
Huang Y, Guo L, Qiu J, Chen X, Hu-Li J, Siebenlist U, Williamson PR, Urban JF Jr, Paul WE. Huang Y, et al. Among authors: paul we. Nat Immunol. 2015 Feb;16(2):161-9. doi: 10.1038/ni.3078. Epub 2014 Dec 22. Nat Immunol. 2015. PMID: 25531830 Free PMC article.
Innate lymphoid cells (ILCs) are lymphocyte-like cells that lack T cell or B cell antigen receptors and mediate protective and repair functions through cytokine secretion. Among these, type 2 ILCs (ILC2 cells) are able to produce type 2 cytokines. We report t …
Innate lymphoid cells (ILCs) are lymphocyte-like cells that lack T cell or B cell antigen receptors and mediate protective and repair …
Basophils and type 2 immunity.
Min B, Paul WE. Min B, et al. Among authors: paul we. Curr Opin Hematol. 2008 Jan;15(1):59-63. doi: 10.1097/MOH.0b013e3282f13ce8. Curr Opin Hematol. 2008. PMID: 18043247 Free PMC article. Review.
Basophils are potent IL-4-producing cells and may contribute to the process of polarizing immune responses. RECENT FINDINGS: Although basophils represent fewer than 0.5% of blood leukocytes, their frequency dramatically increases under certain circumstances, particularly T …
Basophils are potent IL-4-producing cells and may contribute to the process of polarizing immune responses. RECENT FINDINGS: Although …
Inflammatory group 2 innate lymphoid cells.
Huang Y, Paul WE. Huang Y, et al. Among authors: paul we. Int Immunol. 2016 Jan;28(1):23-8. doi: 10.1093/intimm/dxv044. Epub 2015 Aug 1. Int Immunol. 2016. PMID: 26232596 Free PMC article. Review.
Group 2 innate lymphoid cells (ILC2 cells) are able to produce type 2 cytokines and to mediate type 2 immune protection and tissue homeostasis. ...They can be mobilized by distinct types of infections to develop into nILC2-like or ILC3-like cells, functioning in correspond …
Group 2 innate lymphoid cells (ILC2 cells) are able to produce type 2 cytokines and to mediate type 2 immune protection and tissue ho …
How are T(H)2-type immune responses initiated and amplified?
Paul WE, Zhu J. Paul WE, et al. Nat Rev Immunol. 2010 Apr;10(4):225-35. doi: 10.1038/nri2735. Nat Rev Immunol. 2010. PMID: 20336151 Free PMC article. Review.
CD4(+) T helper (T(H)) cells have crucial roles in orchestrating adaptive immune responses. T(H)2 cells control immunity to extracellular parasites and all forms of allergic inflammatory responses. ...Here we discuss the involvement of allergen- and parasite product …
CD4(+) T helper (T(H)) cells have crucial roles in orchestrating adaptive immune responses. T(H)2 cells control immunity to extracell …
Cytokine-induced cytokine production by conventional and innate lymphoid cells.
Guo L, Junttila IS, Paul WE. Guo L, et al. Among authors: paul we. Trends Immunol. 2012 Dec;33(12):598-606. doi: 10.1016/j.it.2012.07.006. Epub 2012 Sep 5. Trends Immunol. 2012. PMID: 22959641 Free PMC article. Review.
Innate immune and differentiated T cells produce signature cytokines in response to cytokine stimulation. Optimal production requires stimulation by an NF-kappaB inducer, most commonly an interleukin (IL)-1 family member, and a STAT activator. ...Cytokine
Innate immune and differentiated T cells produce signature cytokines in response to cytokine stimulation. Optimal produ …
Heterogeneity and plasticity of T helper cells.
Zhu J, Paul WE. Zhu J, et al. Among authors: paul we. Cell Res. 2010 Jan;20(1):4-12. doi: 10.1038/cr.2009.138. Epub 2009 Dec 15. Cell Res. 2010. PMID: 20010916 Free PMC article. Review.
Subsets of the same lineage may express different effector cytokines, reside at different locations or give rise to cells with different fates, whereas cells from different lineages may secrete common cytokines, such as IL-2, IL-9 and IL-10, resulting in massive het …
Subsets of the same lineage may express different effector cytokines, reside at different locations or give rise to cells with differ …
Interleukin 4 receptor: signaling mechanisms.
Keegan AD, Nelms K, Wang LM, Pierce JH, Paul WE. Keegan AD, et al. Among authors: paul we. Immunol Today. 1994 Sep;15(9):423-32. doi: 10.1016/0167-5699(94)90272-0. Immunol Today. 1994. PMID: 7945783 Review.
Achsah Keegan and colleagues consider the signaling mechanisms utilized by the interleukin 4 (IL-4) receptor and review evidence suggesting that these mechanisms can account for the known responses of hematopoietic and non-hematopoietic cells to IL-4. Most of these data ha …
Achsah Keegan and colleagues consider the signaling mechanisms utilized by the interleukin 4 (IL-4) receptor and review evidence suggesting …
IL-1beta strikingly enhances antigen-driven CD4 and CD8 T-cell responses.
Ben-Sasson SZ, Wang K, Cohen J, Paul WE. Ben-Sasson SZ, et al. Among authors: paul we. Cold Spring Harb Symp Quant Biol. 2013;78:117-24. doi: 10.1101/sqb.2013.78.021246. Epub 2013 Oct 3. Cold Spring Harb Symp Quant Biol. 2013. PMID: 24092469 Review.
Protective immune response requires massive expansion of antigen-triggered naive cells, extensive differentiation into effector cells, migration of effectors into the periphery, and generation of a functional memory compartment. ...CD4 and CD8 cells primed in the presence …
Protective immune response requires massive expansion of antigen-triggered naive cells, extensive differentiation into effector cells …
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