Study protocol for a multiarm, randomized controlled trial to determine the effectiveness of community-based frailty rehabilitation to improve physical function in older adults: The OPTIMAL Fitness Trial.
Papaioannou A, Kennedy C, Lee J, Hewston P, McArthur C, Maharaj S, Adachi J, Boulos P, Bobba R, Rabinovich A, McKenna B, Palubiski L, Mangin D, Thabane L, Marr S, Kaasalainen S, Tarride JÉ, Theou O, Armstrong D, Negm A, Noseworthy M, Rockwood K, Dolovich L, Abu Alrob H, Hladysh G, Thompson K, Ioannidis G.
Papaioannou A, et al. Among authors: rockwood k.
PLoS One. 2026 Mar 12;21(3):e0343338. doi: 10.1371/journal.pone.0343338. eCollection 2026.
PLoS One. 2026.
PMID: 41818185
Free PMC article.
Evidence regarding the clinical effectiveness of community-based frailty interventions is limited. Frailty rehabilitation has the potential to be an accessible community-based intervention that may enable independence. ...The results from the OPTIMAL Fitne …
Evidence regarding the clinical effectiveness of community-based frailty interventions is limited. Frailty rehabilitati …