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Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. Takahashi K, et al. Cell. 2007 Nov 30;131(5):861-72. doi: 10.1016/j.cell.2007.11.019. Cell. 2007. PMID: 18035408 Free article.
We previously reported generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from mouse somatic cells by transduction of four defined transcription factors. Here, we demonstrate the generation of iPS …
We previously reported generation of induced pluripotent stem (iPS) cells, capable of germline transmission, from mo
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
Takahashi K, Yamanaka S. Takahashi K, et al. Cell. 2006 Aug 25;126(4):663-76. doi: 10.1016/j.cell.2006.07.024. Epub 2006 Aug 10. Cell. 2006. PMID: 16904174 Free article.
Little is known about factors that induce this reprogramming. Here, we demonstrate induction of pluripotent stem cells from mouse embryonic or adult fibroblasts by introducing four factors, Oct3/4, Sox2, c-Myc, …
Little is known about factors that induce this reprogramming. Here, we demonstrate induction of pluripotent stem