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Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions.
Wong HS, Dighe PA, Mezera V, Monternier PA, Brand MD. Wong HS, et al. J Biol Chem. 2017 Oct 13;292(41):16804-16809. doi: 10.1074/jbc.R117.789271. Epub 2017 Aug 24. J Biol Chem. 2017. PMID: 28842493 Free PMC article. Review.
Mitochondrial production of superoxide and hydrogen peroxide is potentially important in cell signaling and disease. Eleven distinct mitochondrial sites that differ markedly in capacity are known to leak electrons to …
Mitochondrial production of superoxide and hydrogen peroxide is potentially important in cell signaling a …
The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production.
Goncalves RLS, Watson MA, Wong HS, Orr AL, Brand MD. Goncalves RLS, et al. Among authors: wong hs. Redox Biol. 2020 Jan;28:101341. doi: 10.1016/j.redox.2019.101341. Epub 2019 Oct 9. Redox Biol. 2020. PMID: 31627168 Free PMC article.
The use of S1QELs and S3QELs is a powerful new way to measure the relative contributions of different mitochondrial sites to muscle hydrogen peroxide production under different conditions. Our results show that mitochondr …
The use of S1QELs and S3QELs is a powerful new way to measure the relative contributions of different mitochondrial sites …