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Mitochondria-Associated Membranes and ER Stress.
van Vliet AR, Agostinis P. van Vliet AR, et al. Curr Top Microbiol Immunol. 2018;414:73-102. doi: 10.1007/82_2017_2. Curr Top Microbiol Immunol. 2018. PMID: 28349285 Review.
The endoplasmic reticulum (ER) is a crucial organelle for coordinating cellular Ca(2+) signaling and protein synthesis and folding. ...The contact sites that the ER form with mitochondria is a hot topic in research, and the nature of the so-call …
The endoplasmic reticulum (ER) is a crucial organelle for coordinating cellular Ca(2+) signaling and protein synthesis …
Non-canonical function of IRE1alpha determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics.
Carreras-Sureda A, Jaña F, Urra H, Durand S, Mortenson DE, Sagredo A, Bustos G, Hazari Y, Ramos-Fernández E, Sassano ML, Pihán P, van Vliet AR, González-Quiroz M, Torres AK, Tapia-Rojas C, Kerkhofs M, Vicente R, Kaufman RJ, Inestrosa NC, Gonzalez-Billault C, Wiseman RL, Agostinis P, Bultynck G, Court FA, Kroemer G, Cárdenas JC, Hetz C. Carreras-Sureda A, et al. Among authors: van vliet ar. Nat Cell Biol. 2019 Jun;21(6):755-767. doi: 10.1038/s41556-019-0329-y. Epub 2019 May 20. Nat Cell Biol. 2019. PMID: 31110288 Free PMC article.
Mitochondria-associated membranes (MAMs) are central microdomains that fine-tune bioenergetics by the local transfer of calcium from the endoplasmic reticulum to the mitochondrial matrix. Here, we report an unexpected function of the endoplas …
Mitochondria-associated membranes (MAMs) are central microdomains that fine-tune bioenergetics by the local transfer of …
Mitochondria-Associated Membranes As Networking Platforms and Regulators of Cancer Cell Fate.
Sassano ML, van Vliet AR, Agostinis P. Sassano ML, et al. Among authors: van vliet ar. Front Oncol. 2017 Aug 18;7:174. doi: 10.3389/fonc.2017.00174. eCollection 2017. Front Oncol. 2017. PMID: 28868254 Free PMC article. Review.
The tight cross talk between two essential organelles of the cell, the endoplasmic reticulum (ER) and mitochondria, is spatially and functionally regulated by specific microdomains known as the mitochondria-associated membranes (MA …
The tight cross talk between two essential organelles of the cell, the endoplasmic reticulum (ER) and mitochondria …
New functions of mitochondria associated membranes in cellular signaling.
van Vliet AR, Verfaillie T, Agostinis P. van Vliet AR, et al. Biochim Biophys Acta. 2014 Oct;1843(10):2253-62. doi: 10.1016/j.bbamcr.2014.03.009. Epub 2014 Mar 15. Biochim Biophys Acta. 2014. PMID: 24642268 Free article. Review.
In all eukaryotic cells, the endoplasmic reticulum (ER) and the mitochondria establish a tight interplay, which is structurally and functionally modulated through a proteinaceous tether formed at specific subdomains of the ER membrane, designate …
In all eukaryotic cells, the endoplasmic reticulum (ER) and the mitochondria establish a tight interplay, which …
Interactome Analysis of the ER Stress Sensor Perk Uncovers Key Components of ER-Mitochondria Contact Sites and Ca(2+) Signalling.
Sassano ML, Derua R, Waelkens E, Agostinis P, van Vliet AR. Sassano ML, et al. Among authors: van vliet ar. Contact (Thousand Oaks). 2021 Nov 29;4:25152564211052392. doi: 10.1177/25152564211052392. eCollection 2021 Jan-Dec. Contact (Thousand Oaks). 2021. PMID: 37366380 Free PMC article.
We recently reported that the ER stress kinase PERK regulates ER-mitochondria appositions and ER- plasma membrane (ER-PM) contact sites, independent of its canonical role in the unfolded protein response. ...In this report, we further int …
We recently reported that the ER stress kinase PERK regulates ER-mitochondria appositions and ER- plasma …