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19 results

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Page 1
Linezolid in methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a randomized, controlled study.
Wunderink RG, Niederman MS, Kollef MH, Shorr AF, Kunkel MJ, Baruch A, McGee WT, Reisman A, Chastre J. Wunderink RG, et al. Among authors: shorr af. Clin Infect Dis. 2012 Mar 1;54(5):621-9. doi: 10.1093/cid/cir895. Epub 2012 Jan 12. Clin Infect Dis. 2012. PMID: 22247123 Clinical Trial.
BACKGROUND: Post hoc analyses of clinical trial data suggested that linezolid may be more effective than vancomycin for treatment of methicillin-resistant Staphylococcus aureus (MRSA) nosocomial pneumonia. This study prospectively assessed efficacy and safety of lin …
BACKGROUND: Post hoc analyses of clinical trial data suggested that linezolid may be more effective than vancomycin for treatment of methici …
Epidemiology of staphylococcal resistance.
Shorr AF. Shorr AF. Clin Infect Dis. 2007 Sep 15;45 Suppl 3:S171-6. doi: 10.1086/519473. Clin Infect Dis. 2007. PMID: 17712743 Review.
An understanding of the prevalence of resistant Staphylococcus aureus and the risk factors for infection with resistant isolates is essential to help clinicians choose appropriate antibiotic therapy. Selection pressure due to prior and inappropriate antibioti …
An understanding of the prevalence of resistant Staphylococcus aureus and the risk factors for infection with resistant
Epidemiology and economic impact of meticillin-resistant Staphylococcus aureus: review and analysis of the literature.
Shorr AF. Shorr AF. Pharmacoeconomics. 2007;25(9):751-68. doi: 10.2165/00019053-200725090-00004. Pharmacoeconomics. 2007. PMID: 17803334 Review.
In the past 2 decades, meticillin-resistant Staphylococcus aureus (MRSA) has become an increasingly prevalent problem in healthcare, both in acute care institutions and in the community. ...Current opinion favours rational prescribing to maximise therapeutic benefit …
In the past 2 decades, meticillin-resistant Staphylococcus aureus (MRSA) has become an increasingly prevalent problem in healt …
Bloodstream Infection in the Intensive Care Unit: Evolving Epidemiology and Microbiology.
Munro C, Zilberberg MD, Shorr AF. Munro C, et al. Among authors: shorr af. Antibiotics (Basel). 2024 Jan 26;13(2):123. doi: 10.3390/antibiotics13020123. Antibiotics (Basel). 2024. PMID: 38391509 Free PMC article. Review.
BSIs complicating the care of persons suffering from Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection significantly heighten the risk for death compared to patients who develop ICU BSIs but who are not infected with SARS-CoV-2. Furthermore, rates of antimicr …
BSIs complicating the care of persons suffering from Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection significantly he …
Microbiology, empiric therapy and its impact on the outcomes of nonventilated hospital-acquired, ventilated hospital-acquired, and ventilator-associated bacterial pneumonia in the United States, 2014-2019.
Zilberberg MD, Nathanson BH, Puzniak LA, Shorr AF. Zilberberg MD, et al. Among authors: shorr af. Infect Control Hosp Epidemiol. 2022 Mar;43(3):277-283. doi: 10.1017/ice.2021.464. Infect Control Hosp Epidemiol. 2022. PMID: 35322770
S. aureus (majority methicillin-susceptible) was the most frequently isolated organism, followed P. aeruginosa, K. pneumoniae, and E. coli with variations across the conditions. Rates of carbapenem resistance were highest in VABP (9.1%) and to third-generation cephalospori …
S. aureus (majority methicillin-susceptible) was the most frequently isolated organism, followed P. aeruginosa, K. pneumoniae, and E. coli w …
Epidemiology of healthcare-associated pneumonia (HCAP).
Zilberberg MD, Shorr AF. Zilberberg MD, et al. Among authors: shorr af. Semin Respir Crit Care Med. 2009 Feb;30(1):10-5. doi: 10.1055/s-0028-1119804. Epub 2009 Feb 6. Semin Respir Crit Care Med. 2009. PMID: 19199182 Review.
Although patients with HCAP present from the community, the epidemiology and bacteriology of HCAP belie the community label. As such, highly resistant pathogens such as methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa are commonly …
Although patients with HCAP present from the community, the epidemiology and bacteriology of HCAP belie the community label. As such, …
Healthcare-associated bloodstream infection: A distinct entity? Insights from a large U.S. database.
Shorr AF, Tabak YP, Killian AD, Gupta V, Liu LZ, Kollef MH. Shorr AF, et al. Crit Care Med. 2006 Oct;34(10):2588-95. doi: 10.1097/01.CCM.0000239121.09533.09. Crit Care Med. 2006. PMID: 16915117
Of all bacterial bloodstream infections, methicillin-resistant Staphylococcus aureus was associated with the highest crude mortality rate (22.5%), the longest mean length of stay (11.1 +/- 10.7 days), and the highest median total charges ($36,109). ...CONCLUSIONS: H …
Of all bacterial bloodstream infections, methicillin-resistant Staphylococcus aureus was associated with the highest crude mor …
Bacteremia in Staphylococcus aureus pneumonia: outcomes and epidemiology.
Schreiber MP, Chan CM, Shorr AF. Schreiber MP, et al. Among authors: shorr af. J Crit Care. 2011 Aug;26(4):395-401. doi: 10.1016/j.jcrc.2010.09.002. Epub 2010 Oct 30. J Crit Care. 2011. PMID: 21036521
PURPOSE: Staphylococcus aureus represents a major cause of pneumonia in critically ill patients. Although bacteremia may complicate S aureus pneumonia, the epidemiology of and outcomes associated with bacteremia in this syndrome are poorly described. ...RESULTS: The …
PURPOSE: Staphylococcus aureus represents a major cause of pneumonia in critically ill patients. Although bacteremia may complicate S …
Outcomes associated with bacteremia in the setting of methicillin-resistant Staphylococcus aureus pneumonia: a retrospective cohort study.
Shorr AF, Zilberberg MD, Micek ST, Kollef MH. Shorr AF, et al. Crit Care. 2015 Sep 3;19(1):312. doi: 10.1186/s13054-015-1029-z. Crit Care. 2015. PMID: 26335247 Free PMC article.
INTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) remains an important pathogen in pneumonia. Bacteremia may secondarily complicate MRSA pneumonia. The epidemiology and outcomes associated with bacteremia in the setting of MRSA pneumonia are un …
INTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) remains an important pathogen in pneumonia. Bacteremia may se …
Morbidity and cost burden of methicillin-resistant Staphylococcus aureus in early onset ventilator-associated pneumonia.
Shorr AF, Tabak YP, Gupta V, Johannes RS, Liu LZ, Kollef MH. Shorr AF, et al. Crit Care. 2006;10(3):R97. doi: 10.1186/cc4934. Epub 2006 Jun 29. Crit Care. 2006. PMID: 16808853 Free PMC article.
INTRODUCTION: To gain a better understanding of the clinical and economic outcomes associated with methicillin-resistant Staphylococcus aureus (MRSA) infection in patients with early onset ventilator-associated pneumonia (VAP), we retrospectively analyzed a multihos …
INTRODUCTION: To gain a better understanding of the clinical and economic outcomes associated with methicillin-resistant Staphyloc
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