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Page 1
SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway.
Gu X, Orozco JM, Saxton RA, Condon KJ, Liu GY, Krawczyk PA, Scaria SM, Harper JW, Gygi SP, Sabatini DM. Gu X, et al. Among authors: condon kj. Science. 2017 Nov 10;358(6364):813-818. doi: 10.1126/science.aao3265. Science. 2017. PMID: 29123071 Free PMC article.
MFSD12 mediates the import of cysteine into melanosomes and lysosomes.
Adelmann CH, Traunbauer AK, Chen B, Condon KJ, Chan SH, Kunchok T, Lewis CA, Sabatini DM. Adelmann CH, et al. Among authors: condon kj. Nature. 2020 Dec;588(7839):699-704. doi: 10.1038/s41586-020-2937-x. Epub 2020 Nov 18. Nature. 2020. PMID: 33208952 Free PMC article.
Fumarate is a terminal electron acceptor in the mammalian electron transport chain.
Spinelli JB, Rosen PC, Sprenger HG, Puszynska AM, Mann JL, Roessler JM, Cangelosi AL, Henne A, Condon KJ, Zhang T, Kunchok T, Lewis CA, Chandel NS, Sabatini DM. Spinelli JB, et al. Among authors: condon kj. Science. 2021 Dec 3;374(6572):1227-1237. doi: 10.1126/science.abi7495. Epub 2021 Dec 2. Science. 2021. PMID: 34855504 Free PMC article.
Amino acids and KLHL22 do not activate mTORC1 via DEPDC5 degradation.
Valenstein ML, Lalgudi PV, Kedir JF, Condon KJ, Platzek A, Freund DG, Taylor MS, Xu Y, Chivukula RR, Sabatini DM. Valenstein ML, et al. Among authors: condon kj. Nature. 2025 Jan;637(8045):E11-E14. doi: 10.1038/s41586-024-07974-0. Epub 2025 Jan 8. Nature. 2025. PMID: 39780017 No abstract available.
Nutrient regulation of mTORC1 at a glance.
Condon KJ, Sabatini DM. Condon KJ, et al. J Cell Sci. 2019 Nov 13;132(21):jcs222570. doi: 10.1242/jcs.222570. J Cell Sci. 2019. PMID: 31722960 Free PMC article. Review.
Discovery of BMS-986408, a First-In-Class Dual DGKα and DGKζ Inhibitor That Unleashes PD-1 Checkpoint and CAR T-Cell Immunotherapies.
Wichroski M, Liu SQ, Zasadil LM, Benci JL, Gedeon PC, Condon KJ, Joshi S, Posy S, Carlson P, Maier A, Shen J, Kureshi R, Amako Y, Wang T, Powles RL, Li Y, Lai T, Katsyv I, Qiu H, Qi H, Wong J, Zhao D, Banas D, Onorato J, Locke G, Chen X, Chou WC, Cook E, Witt AE, Barbieri CM, Zhang H, Olsen JB, Font-Tello A, Drokhlyansky E, Grünenfelder DC, Chupak L, Longmire TA, Jones JC, Hollmann TJ, Kugler DG, Feder JN, Bueno R, Wain J, Sivakumar P, Liu Y, Dougan SK, Paweletz CP, Barbie DA, Lees E. Wichroski M, et al. Among authors: condon kj. Cancer Immunol Res. 2025 Jun 12. doi: 10.1158/2326-6066.CIR-25-0156. Online ahead of print. Cancer Immunol Res. 2025. PMID: 40506249
Structural Basis for Gating and Activation of RyR1.
des Georges A, Clarke OB, Zalk R, Yuan Q, Condon KJ, Grassucci RA, Hendrickson WA, Marks AR, Frank J. des Georges A, et al. Among authors: condon kj. Cell. 2016 Sep 22;167(1):145-157.e17. doi: 10.1016/j.cell.2016.08.075. Cell. 2016. PMID: 27662087 Free PMC article.
Architecture of the human GATOR1 and GATOR1-Rag GTPases complexes.
Shen K, Huang RK, Brignole EJ, Condon KJ, Valenstein ML, Chantranupong L, Bomaliyamu A, Choe A, Hong C, Yu Z, Sabatini DM. Shen K, et al. Among authors: condon kj. Nature. 2018 Apr 5;556(7699):64-69. doi: 10.1038/nature26158. Epub 2018 Mar 28. Nature. 2018. PMID: 29590090 Free PMC article.
13 results