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Page 1
Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.
Murtaza N, Cheng AA, Brown CO, Meka DP, Hong S, Uy JA, El-Hajjar J, Pipko N, Unda BK, Schwanke B, Xing S, Thiruvahindrapuram B, Engchuan W, Trost B, Deneault E, Calderon de Anda F, Doble BW, Ellis J, Anagnostou E, Bader GD, Scherer SW, Lu Y, Singh KK. Murtaza N, et al. Among authors: deneault e. Cell Rep. 2022 Nov 22;41(8):111678. doi: 10.1016/j.celrep.2022.111678. Cell Rep. 2022. PMID: 36417873 Free article.
Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.
C Yuen RK, Merico D, Bookman M, L Howe J, Thiruvahindrapuram B, Patel RV, Whitney J, Deflaux N, Bingham J, Wang Z, Pellecchia G, Buchanan JA, Walker S, Marshall CR, Uddin M, Zarrei M, Deneault E, D'Abate L, Chan AJ, Koyanagi S, Paton T, Pereira SL, Hoang N, Engchuan W, Higginbotham EJ, Ho K, Lamoureux S, Li W, MacDonald JR, Nalpathamkalam T, Sung WW, Tsoi FJ, Wei J, Xu L, Tasse AM, Kirby E, Van Etten W, Twigger S, Roberts W, Drmic I, Jilderda S, Modi BM, Kellam B, Szego M, Cytrynbaum C, Weksberg R, Zwaigenbaum L, Woodbury-Smith M, Brian J, Senman L, Iaboni A, Doyle-Thomas K, Thompson A, Chrysler C, Leef J, Savion-Lemieux T, Smith IM, Liu X, Nicolson R, Seifer V, Fedele A, Cook EH, Dager S, Estes A, Gallagher L, Malow BA, Parr JR, Spence SJ, Vorstman J, Frey BJ, Robinson JT, Strug LJ, Fernandez BA, Elsabbagh M, Carter MT, Hallmayer J, Knoppers BM, Anagnostou E, Szatmari P, Ring RH, Glazer D, Pletcher MT, Scherer SW. C Yuen RK, et al. Among authors: deneault e. Nat Neurosci. 2017 Apr;20(4):602-611. doi: 10.1038/nn.4524. Epub 2017 Mar 6. Nat Neurosci. 2017. PMID: 28263302 Free PMC article.
Activation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.
Fiesel FC, Bustillos BA, Watzlawik JO, Chen CXQ, Berryer MH, Zhang J, Boneski PK, Hayes CS, Bredenberg JM, Deneault E, You Z, Abdien N, Aprahamian N, Goldsmith TM, Baninameh Z, Cocker LT, Zhang H, Goldberg MS, Fon EA, Trempe JF, Virdee S, Durcan TM, Springer W. Fiesel FC, et al. Among authors: deneault e. Autophagy. 2025 Dec;21(12):2750-2770. doi: 10.1080/15548627.2025.2531025. Epub 2025 Jul 18. Autophagy. 2025. PMID: 40624741 Free PMC article.
Glucosylceramide-induced ectosomes propagate pathogenic α-synuclein in Parkinson's disease.
Jacquemyn J, Marriott B, Chang J, Iftikhar E, Chik K, Lee NYJ, Rubio Atonal LF, Green C, Wong J, Acevedo-Morantes C, Chen CX, Nicouleau M, You Z, Deneault E, Abdian N, Durcan TM, Jackson J, Ioannou MS. Jacquemyn J, et al. Among authors: deneault e. Nat Cell Biol. 2026 Mar;28(3):492-506. doi: 10.1038/s41556-026-01871-6. Epub 2026 Feb 12. Nat Cell Biol. 2026. PMID: 41680444
Disruption of DDX53 coding sequence has limited impact on iPSC-derived human NGN2 neurons.
Faheem M, Deneault E, Alexandrova R, Rodrigues DC, Pellecchia G, Shum C, Zarrei M, Piekna A, Wei W, Howe JL, Thiruvahindrapuram B, Lamoureux S, Ross PJ, Bradley CA, Ellis J, Scherer SW. Faheem M, et al. Among authors: deneault e. BMC Med Genomics. 2023 Jan 12;16(1):5. doi: 10.1186/s12920-022-01425-3. BMC Med Genomics. 2023. PMID: 36635662 Free PMC article.
30 results