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Page 1
Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex.
Horn-Ghetko D, Hopf LVM, Tripathi-Giesgen I, Du J, Kostrhon S, Vu DT, Beier V, Steigenberger B, Prabu JR, Stier L, Bruss EM, Mann M, Xiong Y, Schulman BA. Horn-Ghetko D, et al. Among authors: kostrhon s. Nat Struct Mol Biol. 2024 Jul;31(7):1083-1094. doi: 10.1038/s41594-024-01257-y. Epub 2024 Apr 11. Nat Struct Mol Biol. 2024. PMID: 38605244 Free PMC article.
A Pro-Fluorescent Ubiquitin-Based Probe to Monitor Cysteine-Based E3 Ligase Activity.
Pérez Berrocal DA, Vishwanatha TM, Horn-Ghetko D, Botsch JJ, Hehl LA, Kostrhon S, Misra M, Ðikić I, Geurink PP, van Dam H, Schulman BA, Mulder MPC. Pérez Berrocal DA, et al. Among authors: kostrhon s. Angew Chem Int Ed Engl. 2023 Aug 7;62(32):e202303319. doi: 10.1002/anie.202303319. Epub 2023 Jun 27. Angew Chem Int Ed Engl. 2023. PMID: 37272691
PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Appel LM, Franke V, Bruno M, Grishkovskaya I, Kasiliauskaite A, Kaufmann T, Schoeberl UE, Puchinger MG, Kostrhon S, Ebenwaldner C, Sebesta M, Beltzung E, Mechtler K, Lin G, Vlasova A, Leeb M, Pavri R, Stark A, Akalin A, Stefl R, Bernecky C, Djinovic-Carugo K, Slade D. Appel LM, et al. Among authors: kostrhon s. Nat Commun. 2021 Oct 19;12(1):6078. doi: 10.1038/s41467-021-26360-2. Nat Commun. 2021. PMID: 34667177 Free PMC article.
SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation.
Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, Opravil S, Hudecz O, Mechtler K, Warren G, Slade D. Kaufmann T, et al. Among authors: kostrhon s. J Cell Sci. 2016 Dec 15;129(24):4607-4621. doi: 10.1242/jcs.192633. Epub 2016 Nov 14. J Cell Sci. 2016. PMID: 27875273 Free PMC article.
A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Kaufmann T, Grishkovskaya I, Polyansky AA, Kostrhon S, Kukolj E, Olek KM, Herbert S, Beltzung E, Mechtler K, Peterbauer T, Gotzmann J, Zhang L, Hartl M, Zagrovic B, Elsayad K, Djinovic-Carugo K, Slade D. Kaufmann T, et al. Among authors: kostrhon s. Nucleic Acids Res. 2017 Sep 19;45(16):9741-9759. doi: 10.1093/nar/gkx604. Nucleic Acids Res. 2017. PMID: 28934471 Free PMC article.