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Page 1
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
DaRosa PA, Penchev I, Gumbin SC, Scavone F, Wąchalska M, Paulo JA, Ordureau A, Peter JJ, Kulathu Y, Harper JW, Becker T, Beckmann R, Kopito RR. DaRosa PA, et al. Among authors: kulathu y. Nature. 2024 Mar;627(8003):445-452. doi: 10.1038/s41586-024-07073-0. Epub 2024 Feb 21. Nature. 2024. PMID: 38383785 Free PMC article.
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.
Makhlouf L, Peter JJ, Magnussen HM, Thakur R, Millrine D, Minshull TC, Harrison G, Varghese J, Lamoliatte F, Foglizzo M, Macartney T, Calabrese AN, Zeqiraj E, Kulathu Y. Makhlouf L, et al. Among authors: kulathu y. Nature. 2024 Mar;627(8003):437-444. doi: 10.1038/s41586-024-07093-w. Epub 2024 Feb 21. Nature. 2024. PMID: 38383789 Free PMC article.
VCP/p97-associated proteins are binders and debranching enzymes of K48-K63-branched ubiquitin chains.
Lange SM, McFarland MR, Lamoliatte F, Carroll T, Krshnan L, Pérez-Ràfols A, Kwasna D, Shen L, Wallace I, Cole I, Armstrong LA, Knebel A, Johnson C, De Cesare V, Kulathu Y. Lange SM, et al. Among authors: kulathu y. Nat Struct Mol Biol. 2024 Dec;31(12):1872-1887. doi: 10.1038/s41594-024-01354-y. Epub 2024 Jul 8. Nat Struct Mol Biol. 2024. PMID: 38977901 Free PMC article.
Linking K29-Ub chains to biology.
Lange SM, Kulathu Y. Lange SM, et al. Among authors: kulathu y. Nat Chem Biol. 2021 Aug;17(8):843-844. doi: 10.1038/s41589-021-00833-3. Nat Chem Biol. 2021. PMID: 34239126 No abstract available.
Cross-species interactome analysis uncovers a conserved selective autophagy mechanism for protein quality control in plants.
Sánchez de Medina Hernández V, Nava-García MM, Bianchi A, Clavel M, Papareddy RK, Benchalel L, Andreev VI, Mathur V, Mohseni A, García-León M, Gao P, de la Concepción JC, Picchianti L, Grujic N, Kobylinska R, Abdrakhmanov A, Duvergé H, Anand G, Leibrock N, Ma J, Raffeiner M, Crawford TS, Argirò L, Matuszkiewicz M, Wun CL, Kanne JV, Meinhart A, Roitinger E, Bäurle I, Kang BH, Petersen M, Üstün S, Kulathu Y, Clausen T, Ramundo S, Dagdas Y. Sánchez de Medina Hernández V, et al. Among authors: kulathu y. Dev Cell. 2026 Mar 11;61(3):655-675.e22. doi: 10.1016/j.devcel.2025.11.001. Epub 2025 Dec 1. Dev Cell. 2026. PMID: 41330383 Free article.
46 results