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1

KDM5 histone demethylases repress immune response via suppression of STING.

Wu L, Cao J, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai G, Kales SC, Henderson MJ, Hu X, Jadhav A, Maloney DJ, Simeonov A, Zhu S, Iwasaki A, Hall MD, Cheng X, Shadel GS, Yan Q. Wu L, et al. Among authors: Chen JF. PLoS Biol. 2018 Aug 6;16(8):e2006134. doi: 10.1371/journal.pbio.2006134. eCollection 2018 Aug. PLoS Biol. 2018. PMID: 30080846 Free PMC article.

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2

Adenosine receptors as drug targets--what are the challenges?

Chen JF, Eltzschig HK, Fredholm BB. Chen JF, et al. Nat Rev Drug Discov. 2013 Apr;12(4):265-86. doi: 10.1038/nrd3955. Nat Rev Drug Discov. 2013. PMID: 23535933 Free PMC article. Review.

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3

Reply.

Chen JF, Lin BL. Chen JF, et al. Hepatology. 2018 Oct;68(4):1661. doi: 10.1002/hep.30217. Hepatology. 2018. PMID: 30107047 No abstract available.

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4

Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors.

Zhang W, Yang SL, Yang M, Herrlinger S, Shao Q, Collar JL, Fierro E, Shi Y, Liu A, Lu H, Herring BE, Guo ML, Buch S, Zhao Z, Xu J, Lu Z, Chen JF. Zhang W, et al. Among authors: Chen JF. Nat Commun. 2019 Jun 13;10(1):2612. doi: 10.1038/s41467-019-10497-2. Nat Commun. 2019. PMID: 31197141 Free PMC article.

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5

Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential.

Reis-Sobreiro M, Chen JF, Novitskaya T, You S, Morley S, Steadman K, Gill NK, Eskaros A, Rotinen M, Chu CY, Chung LWK, Tanaka H, Yang W, Knudsen BS, Tseng HR, Rowat AC, Posadas EM, Zijlstra A, Di Vizio D, Freeman MR. Reis-Sobreiro M, et al. Among authors: Chen JF. Cancer Res. 2018 Nov 1;78(21):6086-6097. doi: 10.1158/0008-5472.CAN-18-0608. Epub 2018 Aug 28. Cancer Res. 2018. PMID: 30154147 Free article.

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6

Adenosine and Sleep.

Lazarus M, Chen JF, Huang ZL, Urade Y, Fredholm BB. Lazarus M, et al. Among authors: Chen JF. Handb Exp Pharmacol. 2019;253:359-381. doi: 10.1007/164_2017_36. Handb Exp Pharmacol. 2019. PMID: 28646346 Review.

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7

Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D₁ receptors.

Luo YJ, Li YD, Wang L, Yang SR, Yuan XS, Wang J, Cherasse Y, Lazarus M, Chen JF, Qu WM, Huang ZL. Luo YJ, et al. Among authors: Chen JF. Nat Commun. 2018 Apr 20;9(1):1576. doi: 10.1038/s41467-018-03889-3. Nat Commun. 2018. PMID: 29679009 Free PMC article.

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8

NanoVelcro rare-cell assays for detection and characterization of circulating tumor cells.

Jan YJ, Chen JF, Zhu Y, Lu YT, Chen SH, Chung H, Smalley M, Huang YW, Dong J, Chen LC, Yu HH, Tomlinson JS, Hou S, Agopian VG, Posadas EM, Tseng HR. Jan YJ, et al. Among authors: Chen JF, Chen SH, Chen LC. Adv Drug Deliv Rev. 2018 Feb 1;125:78-93. doi: 10.1016/j.addr.2018.03.006. Epub 2018 Mar 15. Adv Drug Deliv Rev. 2018. PMID: 29551650 Free PMC article. Review.

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9

Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis.

Liu Z, Yan S, Wang J, Xu Y, Wang Y, Zhang S, Xu X, Yang Q, Zeng X, Zhou Y, Gu X, Lu S, Fu Z, Fulton DJ, Weintraub NL, Caldwell RB, Zhang W, Wu C, Liu XL, Chen JF, Ahmad A, Kaddour-Djebbar I, Al-Shabrawey M, Li Q, Jiang X, Sun Y, Sodhi A, Smith L, Hong M, Huo Y. Liu Z, et al. Among authors: Chen JF. Nat Commun. 2017 Sep 19;8(1):584. doi: 10.1038/s41467-017-00551-2. Nat Commun. 2017. PMID: 28928465 Free PMC article.

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10

Highly selective inhibition of IMPDH2 provides the basis of antineuroinflammation therapy.

Liao LX, Song XM, Wang LC, Lv HN, Chen JF, Liu D, Fu G, Zhao MB, Jiang Y, Zeng KW, Tu PF. Liao LX, et al. Among authors: Chen JF. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5986-E5994. doi: 10.1073/pnas.1706778114. Epub 2017 Jul 3. Proc Natl Acad Sci U S A. 2017. PMID: 28674004 Free PMC article.

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