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Page 1
New natural furfural derivatives from the leaves and stems of Pogostemon cablin.
Wang Y, Ding L, Hu Q, Wang C. Wang Y, et al. Nat Prod Res. 2023 Feb;37(3):434-440. doi: 10.1080/14786419.2021.1977805. Epub 2021 Sep 15. Nat Prod Res. 2023. PMID: 34523376
Compound 1 was the first example of natural furfural derivative with a unique C5-C1' linkage between a molecule of furfural and 3-methyl-2-cyclopentenone moiety. ...
Compound 1 was the first example of natural furfural derivative with a unique C5-C1' linkage between a molecule of furfural and 3-met …
Evaluation of 2-benzylidene-1-tetralone derivatives as antagonists of A1 and A2A adenosine receptors.
Legoabe LJ, Van der Walt MM, Terre'Blanche G. Legoabe LJ, et al. Chem Biol Drug Des. 2018 Jan;91(1):234-244. doi: 10.1111/cbdd.13074. Epub 2017 Aug 16. Chem Biol Drug Des. 2018. PMID: 28734058
The 2-benzylidene-1-tetralones bearing a hydroxyl substituent at either position C5, C6 or C7 of ring A displayed favourable adenosine A(1) receptor binding, while C5 hydroxy substitution led to favourable A(2A) adenosine receptor affinity. ...
The 2-benzylidene-1-tetralones bearing a hydroxyl substituent at either position C5, C6 or C7 of ring A displayed favourable adenosin …
A Water-Soluble 5/14-Carbobicyclic Steroid with a trans-9,11-Epoxy Ring from the Marine Dinoflagellate Amphidinium gibbosum: Insights into Late-Stage Diversification of Steroids.
Shen L, Li WS, Yu Y, Sun SH, Wu J. Shen L, et al. Org Lett. 2021 Feb 5;23(3):837-841. doi: 10.1021/acs.orglett.0c04075. Epub 2021 Jan 21. Org Lett. 2021. PMID: 33475383
Its 5/14-carbobicyclic nucleus is proposed to be originated from late-stage oxidative cleavage of the C5-C10 and C8-C9 bonds of beta-sitosterol....
Its 5/14-carbobicyclic nucleus is proposed to be originated from late-stage oxidative cleavage of the C5-C10 and C8-C9 bonds of beta- …
Substituted 4-phenylthiazoles: Development of potent and selective A1, A3 and dual A1/A3 adenosine receptor antagonists.
Abdelrahman A, Yerande SG, Namasivayam V, Klapschinski TA, Alnouri MW, El-Tayeb A, Müller CE. Abdelrahman A, et al. Eur J Med Chem. 2020 Jan 15;186:111879. doi: 10.1016/j.ejmech.2019.111879. Epub 2019 Nov 15. Eur J Med Chem. 2020. PMID: 31780082
In the present study, we optimized the versatile 2-amino-4-phenylthiazole scaffold by introducing substituents at N2 and C5 to obtain A(1) and A(3) AR antagonists including dual-target compounds. ...
In the present study, we optimized the versatile 2-amino-4-phenylthiazole scaffold by introducing substituents at N2 and C5 to obtain …
Neutral Cyclometalated Iridium(III) Complexes Bearing Substituted N-Heterocyclic Carbene (NHC) Ligands for High-Performance Yellow OLED Application.
Liu B, Jabed MA, Guo J, Xu W, Brown SL, Ugrinov A, Hobbie EK, Kilina S, Qin A, Sun W. Liu B, et al. Inorg Chem. 2019 Nov 4;58(21):14377-14388. doi: 10.1021/acs.inorgchem.9b01678. Epub 2019 Oct 18. Inorg Chem. 2019. PMID: 31625389
The NHC ligands were substituted with electron-withdrawing or -donating groups on C4' of the phenyl ring (R = NO(2) (Ir1), CN (Ir2), H (Ir3), OCH(3) (Ir4), N(CH(3))(2) (Ir5)) or C5 of the benzimidazole ring (R = NO(2) (Ir6), N(CH(3))(2) (Ir7)). ...
The NHC ligands were substituted with electron-withdrawing or -donating groups on C4' of the phenyl ring (R = NO(2) (Ir1), CN (Ir2), H (Ir3) …
19 results