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2018 34
2019 75
2020 1
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2025 0

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97 results

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Page 1
Hypothyroidism in the older population.
Leng O, Razvi S. Leng O, et al. Thyroid Res. 2019 Feb 8;12:2. doi: 10.1186/s13044-019-0063-3. eCollection 2019. Thyroid Res. 2019. PMID: 30774717 Free PMC article. Review.
These findings are relevant at a time when treatment with thyroid hormones is increasing and more than 10-15% of people aged over 80 years are prescribed levothyroxine replacement therapy. MAIN BODY: The prevalence of hypothyroidism increases with age. However, the referen …
These findings are relevant at a time when treatment with thyroid hormones is increasing and more than 10-15% of people aged over 80 years a …
Adaptive Introgression: An Untapped Evolutionary Mechanism for Crop Adaptation.
Burgarella C, Barnaud A, Kane NA, Jankowski F, Scarcelli N, Billot C, Vigouroux Y, Berthouly-Salazar C. Burgarella C, et al. Front Plant Sci. 2019 Feb 1;10:4. doi: 10.3389/fpls.2019.00004. eCollection 2019. Front Plant Sci. 2019. PMID: 30774638 Free PMC article. Review.
To respond to the agricultural challenges of this century, there is a strong need for harnessing the genetic variability of crops and adapting them to new conditions. Gene flow, from either the same species or a different species, may be an immediate primary source to wide …
To respond to the agricultural challenges of this century, there is a strong need for harnessing the genetic variability of crops and …
Current progress and questions in germline genetics of prostate cancer.
Isaacs WB, Xu J. Isaacs WB, et al. Asian J Urol. 2019 Jan;6(1):3-9. doi: 10.1016/j.ajur.2018.10.001. Epub 2018 Nov 2. Asian J Urol. 2019. PMID: 30775244 Free PMC article. Review.
Dramatic progress has been made in the area of germline genetics of prostate cancer (PCa) in the past decade. Both common and rare genetic variants with effects on risk ranging from barely detectable to outright practice-changing have been identified. For men with h …
Dramatic progress has been made in the area of germline genetics of prostate cancer (PCa) in the past decade. Both common and rare …
Sjögren's syndrome and systemic lupus erythematosus: links and risks.
Pasoto SG, Adriano de Oliveira Martins V, Bonfa E. Pasoto SG, et al. Open Access Rheumatol. 2019 Jan 29;11:33-45. doi: 10.2147/OARRR.S167783. eCollection 2019. Open Access Rheumatol. 2019. PMID: 30774485 Free PMC article. Review.
The following aspects are addressed: the classification criteria for sSS; differences and similarities between SLE and pSS regarding demographic, clinical, and serological characteristics (including new autoantibodies), as well as comorbidities; the etiopathogenic links between S …
The following aspects are addressed: the classification criteria for sSS; differences and similarities between SLE and pSS regarding demogra …
Targeting androgen receptor-independent pathways in therapy-resistant prostate cancer.
Xu L, Chen J, Liu W, Liang C, Hu H, Huang J. Xu L, et al. Asian J Urol. 2019 Jan;6(1):91-98. doi: 10.1016/j.ajur.2018.11.002. Epub 2018 Nov 28. Asian J Urol. 2019. PMID: 30775252 Free PMC article. Review.
Unfortunately, although the tumor initially responds to the therapy, treatment resistance eventually develops and the disease will progress. It is therefore imperative to identify the mechanisms of therapeutic resistance and novel molecular targets that are independent of …
Unfortunately, although the tumor initially responds to the therapy, treatment resistance eventually develops and the disease will pr …
Systems Biology Approaches Toward Understanding Primary Mitochondrial Diseases.
Maldonado EM, Taha F, Rahman J, Rahman S. Maldonado EM, et al. Front Genet. 2019 Feb 1;10:19. doi: 10.3389/fgene.2019.00019. eCollection 2019. Front Genet. 2019. PMID: 30774647 Free PMC article. Review.
Primary mitochondrial diseases form one of the most common and severe groups of genetic disease, with a birth prevalence of at least 1 in 5000. These disorders are multi-genic and multi-phenotypic (even within the same gene defect) and span the entire age range from prenat …
Primary mitochondrial diseases form one of the most common and severe groups of genetic disease, with a birth prevalence of at least …
Individualized fracture risk assessment: State-of-the-art and room for improvement.
Nguyen TV. Nguyen TV. Osteoporos Sarcopenia. 2018 Mar;4(1):2-10. doi: 10.1016/j.afos.2018.03.001. Epub 2018 Mar 22. Osteoporos Sarcopenia. 2018. PMID: 30775534 Free PMC article. Review.
We propose approaches to improve the accuracy of existing predictive models by incorporating new markers such as genetic factors, bone turnover markers, trabecular bone score, and time-variant factors. ...
We propose approaches to improve the accuracy of existing predictive models by incorporating new markers such as genetic factors, bon …
The crucial role of ZEB2: From development to epithelial-to-mesenchymal transition and cancer complexity.
Fardi M, Alivand M, Baradaran B, Farshdousti Hagh M, Solali S. Fardi M, et al. J Cell Physiol. 2019 Sep;234(9):14783-14799. doi: 10.1002/jcp.28277. Epub 2019 Feb 17. J Cell Physiol. 2019. PMID: 30773635 Review.
In this regard, the understanding of mentioned subjects in the development of normal and cancerous cells could be helpful in cancer complexity of diagnosis and therapy. In this study, we review recent findings about the biological properties of ZEB2 in healthy and cancerou …
In this regard, the understanding of mentioned subjects in the development of normal and cancerous cells could be helpful in cancer complexi …
Familial Melanoma: Diagnostic and Management Implications.
Rossi M, Pellegrini C, Cardelli L, Ciciarelli V, Di Nardo L, Fargnoli MC. Rossi M, et al. Dermatol Pract Concept. 2019 Jan 31;9(1):10-16. doi: 10.5826/dpc.0901a03. eCollection 2019 Jan. Dermatol Pract Concept. 2019. PMID: 30775140 Free PMC article.
Mutations in the other melanoma predisposition genes-CDK4, BAP1, TERT, POT1, ACD, TERF2IP, and MITF-are rare, overall contributing to explain a further 10% of familial clustering of melanoma. The underlying genetic susceptibility remains indeed unexplained for half of mela …
Mutations in the other melanoma predisposition genes-CDK4, BAP1, TERT, POT1, ACD, TERF2IP, and MITF-are rare, overall contributing to explai …
97 results