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REALM-DCM: A Phase 3, Multinational, Randomized, Placebo-Controlled Trial of ARRY-371797 in Patients With Symptomatic LMNA-Related Dilated Cardiomyopathy.
Garcia-Pavia P, Palomares JFR, Sinagra G, Barriales-Villa R, Lakdawala NK, Gottlieb RL, Goldberg RI, Elliott P, Lee P, Li H, Angeli FS, Judge DP, MacRae CA; REALM-DCM Investigators. Garcia-Pavia P, et al. Circ Heart Fail. 2024 Jul;17(7):e011548. doi: 10.1161/CIRCHEARTFAILURE.123.011548. Epub 2024 Jul 9. Circ Heart Fail. 2024. PMID: 38979608 Free PMC article. Clinical Trial.
No significant differences (P>0.05) between groups were observed in the change from baseline at week 24 for all outcomes: 6-minute walk test distance (median difference, 4.9 m [95% CI, -24.2 to 34.1]; P=0.82); Kansas City Cardiomyopathy Questionnaire-physical limitation …
No significant differences (P>0.05) between groups were observed in the change from baseline at week 24 for all outcomes: 6-minute walk t …
High frequencies of circulating IFN-gamma-secreting CD8 cytotoxic T cells specific for a novel MHC class I-restricted Mycobacterium tuberculosis epitope in M. tuberculosis-infected subjects without disease.
Pathan AA, Wilkinson KA, Wilkinson RJ, Latif M, McShane H, Pasvol G, Hill AV, Lalvani A. Pathan AA, et al. Eur J Immunol. 2000 Sep;30(9):2713-21. doi: 10.1002/1521-4141(200009)30:9<2713::AID-IMMU2713>3.0.CO;2-4. Eur J Immunol. 2000. PMID: 11009107 Free article.
We therefore studied subjects who had successfully contained M. tuberculosis infection in vivo, i.e. exposed healthy household contacts and individuals with inactive self-healed pulmonary tuberculosis. ...Rather, our results are consistent with a protective role for these …
We therefore studied subjects who had successfully contained M. tuberculosis infection in vivo, i.e. exposed healthy household contac …
Probable Nipa Palm Wine-Associated Hepatitis A Outbreak after Attending a Funeral Ceremony in Sabah.
Jikal M, Mori D, Yusoff AF, Rai SB, Mukhsam MH, Ali I, Latif LA, Perianayagam AAS, Bernad E, Bailon CCE, Lee LG, Fredolin V, Ahmed K. Jikal M, et al. Am J Trop Med Hyg. 2021 Jul 12;105(3):777-782. doi: 10.4269/ajtmh.21-0036. Am J Trop Med Hyg. 2021. PMID: 34255740 Free PMC article.
Confirmed cases were determined by serum anti-HAV immunoglobulin M and/or for fecal HAV by reverse transcription polymerase chain reaction (RT-PCR). ...
Confirmed cases were determined by serum anti-HAV immunoglobulin M and/or for fecal HAV by reverse transcription polymerase chain rea …
Bisphosphonates inactivate human EGFRs to exert antitumor actions.
Yuen T, Stachnik A, Iqbal J, Sgobba M, Gupta Y, Lu P, Colaianni G, Ji Y, Zhu LL, Kim SM, Li J, Liu P, Izadmehr S, Sangodkar J, Bailey J, Latif Y, Mujtaba S, Epstein S, Davies TF, Bian Z, Zallone A, Aggarwal AK, Haider S, New MI, Sun L, Narla G, Zaidi M. Yuen T, et al. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):17989-94. doi: 10.1073/pnas.1421410111. Epub 2014 Dec 1. Proc Natl Acad Sci U S A. 2014. PMID: 25453081 Free PMC article.
Medetomidine sedation in sheep.
Mohammad FK, Zangana IK, Abdul-Latif AR. Mohammad FK, et al. Zentralbl Veterinarmed A. 1993 Jun;40(5):328-31. doi: 10.1111/j.1439-0442.1993.tb00635.x. Zentralbl Veterinarmed A. 1993. PMID: 8212947
The sedative effect of medetomidine was evaluated in 6 male Awassi sheep. Medetomidine at 40 micrograms/kg, i.m. induced sedation and recumbency in the sheep within 9 +/- 1 and 17 +/- 4 minutes, respectively. ...
The sedative effect of medetomidine was evaluated in 6 male Awassi sheep. Medetomidine at 40 micrograms/kg, i.m. induced sedation and …
Cardiogenic small molecules that enhance myocardial repair by stem cells.
Sadek H, Hannack B, Choe E, Wang J, Latif S, Garry MG, Garry DJ, Longgood J, Frantz DE, Olson EN, Hsieh J, Schneider JW. Sadek H, et al. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6063-8. doi: 10.1073/pnas.0711507105. Epub 2008 Apr 17. Proc Natl Acad Sci U S A. 2008. PMID: 18420817 Free PMC article.
We describe a family of sulfonyl-hydrazone (Shz) small molecules that can trigger cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells, including human mobilized peripheral blood mononuclear cells (M-PBMCs). Small-molecule-enhanced …
We describe a family of sulfonyl-hydrazone (Shz) small molecules that can trigger cardiac mRNA and protein expression in a variety of embryo …
27 results