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2020 2
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Page 1
Antibiotic-Based Conjugates Containing Antimicrobial HLopt2 Peptide: Design, Synthesis, Antimicrobial and Cytotoxic Activities.
Ptaszyńska N, Gucwa K, Olkiewicz K, Łȩgowska A, Okońska J, Ruczyński J, Gitlin-Domagalska A, Dȩbowski D, Milewski S, Rolka K. Ptaszyńska N, et al. Among authors: gitlin domagalska a. ACS Chem Biol. 2019 Oct 18;14(10):2233-2242. doi: 10.1021/acschembio.9b00538. Epub 2019 Sep 25. ACS Chem Biol. 2019. PMID: 31513374
Enhancing Oral Bioavailability of Cyclic RGD Hexa-peptides by the Lipophilic Prodrug Charge Masking Approach: Redirection of Peptide Intestinal Permeability from a Paracellular to Transcellular Pathway.
Schumacher-Klinger A, Fanous J, Merzbach S, Weinmüller M, Reichart F, Räder AFB, Gitlin-Domagalska A, Gilon C, Kessler H, Hoffman A. Schumacher-Klinger A, et al. Among authors: gitlin domagalska a. Mol Pharm. 2018 Aug 6;15(8):3468-3477. doi: 10.1021/acs.molpharmaceut.8b00466. Epub 2018 Jul 25. Mol Pharm. 2018. PMID: 29976060
Matriptase-2: monitoring and inhibiting its proteolytic activity.
Gitlin-Domagalska A, Mangold M, Dębowski D, Ptaszyńska N, Łęgowska A, Gütschow M, Rolka K. Gitlin-Domagalska A, et al. Future Med Chem. 2018 Dec 6. doi: 10.4155/fmc-2018-0346. Online ahead of print. Future Med Chem. 2018. PMID: 30518272
Peptide conjugates of lactoferricin analogues and antimicrobials-Design, chemical synthesis, and evaluation of antimicrobial activity and mammalian cytotoxicity.
Ptaszyńska N, Olkiewicz K, Okońska J, Gucwa K, Łęgowska A, Gitlin-Domagalska A, Dębowski D, Lica J, Heldt M, Milewski S, Ng TB, Rolka K. Ptaszyńska N, et al. Among authors: gitlin domagalska a. Peptides. 2019 Jul;117:170079. doi: 10.1016/j.peptides.2019.04.006. Epub 2019 Apr 5. Peptides. 2019. PMID: 30959143
Antimicrobial Activity of Chimera Peptides Composed of Human Neutrophil Peptide 1 (HNP-1) Truncated Analogues and Bovine Lactoferrampin.
Ptaszyńska N, Gucwa K, Łęgowska A, Dębowski D, Gitlin-Domagalska A, Lica J, Heldt M, Martynow D, Olszewski M, Milewski S, Ng TB, Rolka K. Ptaszyńska N, et al. Among authors: gitlin domagalska a. Bioconjug Chem. 2018 Sep 19;29(9):3060-3071. doi: 10.1021/acs.bioconjchem.8b00440. Epub 2018 Aug 10. Bioconjug Chem. 2018. PMID: 30048118
Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds.
Gitlin-Domagalska A, Dębowski D, Łęgowska A, Stirnberg M, Okońska J, Gütschow M, Rolka K. Gitlin-Domagalska A, et al. Biopolymers. 2017 Nov;108(6). doi: 10.1002/bip.23031. Biopolymers. 2017. PMID: 28555756
Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity.
Ptaszyńska N, Gucwa K, Olkiewicz K, Heldt M, Serocki M, Stupak A, Martynow D, Dębowski D, Gitlin-Domagalska A, Lica J, Łęgowska A, Milewski S, Rolka K. Ptaszyńska N, et al. Among authors: gitlin domagalska a. Int J Mol Sci. 2020 Jun 30;21(13):4696. doi: 10.3390/ijms21134696. Int J Mol Sci. 2020. PMID: 32630159 Free PMC article.
Truncation of Huia versabilis Bowman-Birk inhibitor increases its selectivity, matriptase-1 inhibitory activity and proteolytic stability.
Gitlin-Domagalska A, Dębowski D, Gucwa K, Starego D, Ptaszyńska N, Sieradzan A, Karczyńska A, Samsonov SA, Mangold M, Gütschow M, Łęgowska A, Rolka K. Gitlin-Domagalska A, et al. Biochimie. 2020 Apr-May;171-172:178-186. doi: 10.1016/j.biochi.2020.03.006. Epub 2020 Mar 10. Biochimie. 2020. PMID: 32169666
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