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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1837 2
1845 2
1846 1
1847 3
1848 1
1851 2
1852 2
1853 2
1854 2
1855 1
1856 3
1857 3
1858 4
1859 1
1864 1
1867 3
1868 1
1871 2
1872 2
1873 3
1874 5
1875 3
1876 2
1877 1
1878 3
1879 1
1880 5
1881 1
1882 1
1884 1
1885 2
1886 3
1888 9
1889 4
1890 2
1891 6
1892 6
1893 4
1894 4
1895 3
1896 2
1897 3
1898 2
1899 3
1900 1
1901 4
1902 1
1903 2
1904 1
1906 1
1907 2
1908 1
1910 11
1911 2
1912 8
1913 4
1915 2
1916 9
1918 1
1925 2
1926 5
1927 1
1929 1
1932 1
1940 1
1941 1
1943 1
1945 5
1946 66
1947 59
1948 55
1949 47
1950 60
1951 100
1952 99
1953 74
1954 58
1955 42
1956 52
1957 53
1958 61
1959 52
1960 56
1961 41
1962 42
1963 55
1964 133
1965 163
1966 151
1967 177
1968 169
1969 194
1970 207
1971 198
1972 167
1973 184
1974 143
1975 302
1976 366
1977 342
1978 293
1979 315
1980 384
1981 457
1982 498
1983 590
1984 646
1985 673
1986 856
1987 806
1988 874
1989 912
1990 1032
1991 1161
1992 1171
1993 1153
1994 1219
1995 1288
1996 1271
1997 1255
1998 1263
1999 1314
2000 1568
2001 1466
2002 1404
2003 1434
2004 1535
2005 1404
2006 1500
2007 1576
2008 1531
2009 1496
2010 1549
2011 1487
2012 1538
2013 1571
2014 1584
2015 1564
2016 1585
2017 1535
2018 1577
2019 1694
2020 1779
2021 1724
2022 1678
2023 1600
2024 565

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57,228 results

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Page 1
Teplizumab.
[No authors listed] [No authors listed] 2023 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Nov 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 36701504 Free Books & Documents. Review.
Comprehensive Algorithm for Nasal Ala Reconstruction: Utility of the Auricular Composite Graft.
Chen C, Patel R, Chi J. Chen C, et al. Surg J (N Y). 2018 Apr 18;4(2):e55-e61. doi: 10.1055/s-0038-1639581. eCollection 2018 Apr. Surg J (N Y). 2018. PMID: 29675473 Free PMC article. Review.
Defects of the nasal ala are challenging to reconstruct, given its complex three-dimensional structure. ...In this review, we aim to provide a comprehensive algorithm to guide repair of nasal ala defects. Additionally, we compare our experience using the auricular c …
Defects of the nasal ala are challenging to reconstruct, given its complex three-dimensional structure. ...In this review, we aim to …
VanG- and D-Ala-D-Ser-dependent peptidoglycan synthesis and vancomycin resistance in Clostridioides difficile.
Belitsky BR. Belitsky BR. Mol Microbiol. 2022 Nov;118(5):526-540. doi: 10.1111/mmi.14980. Epub 2022 Sep 30. Mol Microbiol. 2022. PMID: 36065735 Free PMC article.
We isolated spontaneous suppressors of a ddl mutation that allowed cell growth in the absence of D-Ala-D-Ala. The mutations caused constitutive or partly constitutive expression of the vancomycin-inducible vanG operon responsible for the synthesis of D-Ala-D- …
We isolated spontaneous suppressors of a ddl mutation that allowed cell growth in the absence of D-Ala-D-Ala. The mutations ca …
ALA and its clinical impact, from bench to bedside.
Krammer B, Plaetzer K. Krammer B, et al. Photochem Photobiol Sci. 2008 Mar;7(3):283-9. doi: 10.1039/b712847a. Epub 2007 Dec 7. Photochem Photobiol Sci. 2008. PMID: 18389144 Review.
ALA-induced protoporphyrin IX (PpIX) is used for fluorescence diagnosis (ALA-FD) and for fluorescence-guided resection of both (pre)malignant and non-malignant diseases. ...Today, ALA is approved as Levulan for actinic keratoses, the ALA-methyl ester M …
ALA-induced protoporphyrin IX (PpIX) is used for fluorescence diagnosis (ALA-FD) and for fluorescence-guided resection of both …
Intraoperative 5-ALA fluorescence-guided resection of high-grade glioma leads to greater extent of resection with better outcomes: a systematic review.
Eatz TA, Eichberg DG, Lu VM, Di L, Komotar RJ, Ivan ME. Eatz TA, et al. J Neurooncol. 2022 Jan;156(2):233-256. doi: 10.1007/s11060-021-03901-9. Epub 2022 Jan 6. J Neurooncol. 2022. PMID: 34989964 Review.
Of the studies that directly compared the use of 5-ALA to white light (13 of the total analyzed 45, or 28.9%), 5-ALA lead to a better PFS and OS in 88.4 and 67.5% of patients, respectively. When the studies that reported postoperative neurologic outcomes of surgerie …
Of the studies that directly compared the use of 5-ALA to white light (13 of the total analyzed 45, or 28.9%), 5-ALA lead to a …
CPP-Ala-Ala-Tyr-PABA inhibitor analogs with improved selectivity for neurolysin or thimet oligopeptidase.
Dalio FM, Machado MFM, Marcondes MF, Juliano MA, Chagas JR, Cunha RLOR, Oliveira V. Dalio FM, et al. Biochem Biophys Res Commun. 2020 Feb 5;522(2):368-373. doi: 10.1016/j.bbrc.2019.11.097. Epub 2019 Nov 21. Biochem Biophys Res Commun. 2020. PMID: 31761323
These residues are in position to interact with the residue at the P(1)' and/or P(2)' of their substrates (mimicked by the Ala-Ala/P1'-P2' residues of the CPP-Ala-Ala-Tyr-PABA). Therefore, exploring this single difference, the following compounds were …
These residues are in position to interact with the residue at the P(1)' and/or P(2)' of their substrates (mimicked by the Ala-Ala …
d-Alanine Metabolism via d-Ala Aminotransferase by a Marine Gammaproteobacterium, Pseudoalteromonas sp. Strain CF6-2.
Yu Y, Yang J, Teng ZJ, Zheng LY, Sheng Q, Li PY, Fu HH, Li CY, Chen Y, Zhang YZ, Ding JM, Chen XL. Yu Y, et al. Appl Environ Microbiol. 2022 Feb 8;88(3):e0221921. doi: 10.1128/AEM.02219-21. Epub 2021 Nov 24. Appl Environ Microbiol. 2022. PMID: 34818098 Free PMC article.
Thus, Gammaproteobacteria is likely the dominant group to utilize d-Ala via d-Ala aminotransferase to drive the recycling and mineralization of d-Ala in the ocean. ...This study reveals marine d-Ala-utilizing bacteria and the mechanism of their metabol …
Thus, Gammaproteobacteria is likely the dominant group to utilize d-Ala via d-Ala aminotransferase to drive the recycling and …
5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy.
Howley R, Chandratre S, Chen B. Howley R, et al. Bioengineering (Basel). 2023 Apr 21;10(4):496. doi: 10.3390/bioengineering10040496. Bioengineering (Basel). 2023. PMID: 37106683 Free PMC article. Review.
5-Aminolevulinic acid (ALA) is a naturally occurring amino acid synthesized in all nucleated mammalian cells. ...In this review, we would like to describe the heme biosynthesis pathway in which PpIX is produced from ALA and its derivatives, summarize current clinica …
5-Aminolevulinic acid (ALA) is a naturally occurring amino acid synthesized in all nucleated mammalian cells. ...In this review, we w …
A naturally occurring mini-alanyl-tRNA synthetase.
Antika TR, Chrestella DJ, Tseng YK, Yeh YH, Hsiao CD, Wang CC. Antika TR, et al. Commun Biol. 2023 Mar 23;6(1):314. doi: 10.1038/s42003-023-04699-0. Commun Biol. 2023. PMID: 36959394 Free PMC article.
Alanyl-tRNA synthetase (AlaRS) retains a conserved prototype structure throughout its biology, consisting of catalytic, tRNA-recognition, editing, and C-Ala domains. The catalytic and tRNA-recognition domains catalyze aminoacylation, the editing domain hydrolyzes mischarge …
Alanyl-tRNA synthetase (AlaRS) retains a conserved prototype structure throughout its biology, consisting of catalytic, tRNA-recognition, ed …
Predictive biomarkers for 5-ALA-PDT can lead to personalized treatments and overcome tumor-specific resistances.
Mastrangelopoulou M, Grigalavicius M, Raabe TH, Skarpen E, Juzenas P, Peng Q, Berg K, Theodossiou TA. Mastrangelopoulou M, et al. Cancer Rep (Hoboken). 2022 Dec;5(12):e1278. doi: 10.1002/cnr2.1278. Epub 2020 Jul 31. Cancer Rep (Hoboken). 2022. PMID: 32737955 Free PMC article.
Glioblastoma cells were the most resilient to 5-ALA-PDT, while intracellular production of 5-ALA-derived protoporphyrin IX (PpIX) could not account for the recorded PDT responses. ...Inhibition of ABCG2 in U87 cells was the only synergistic adjuvant to 5-ALA- …
Glioblastoma cells were the most resilient to 5-ALA-PDT, while intracellular production of 5-ALA-derived protoporphyrin IX (Pp …
57,228 results
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