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Elevated quinolinic acid levels in cerebrospinal fluid in subacute sclerosing panencephalitis.

Inoue H, Matsushige T, Ichiyama T, Okuno A, Takikawa O, Tomonaga S, Anlar B, Yüksel D, Otsuka Y, Kohno F, Hoshide M, Ohga S, Hasegawa S. Inoue H, et al. Among authors: okuno a. J Neuroimmunol. 2020 Feb 15;339:577088. doi: 10.1016/j.jneuroim.2019.577088. Epub 2019 Oct 18. J Neuroimmunol. 2020. PMID: 31733567

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Partial Identification of Amyloid-β Degrading Activity in Human Serum.

Mikawa R, Okuno A, Yoshimi T, Watanabe A, Maruyama M, Takikawa O. Mikawa R, et al. Among authors: okuno a. Nagoya J Med Sci. 2019 Feb;81(1):55-64. doi: 10.18999/nagjms.81.1.55. Nagoya J Med Sci. 2019. PMID: 30962655 Free PMC article.

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Bacterial Lipoteichoic Acid Attenuates Toll-Like Receptor Dependent Dendritic Cells Activation and Inflammatory Response.

Saito S, Okuno A, Cao DY, Peng Z, Wu HY, Lin SH. Saito S, et al. Among authors: okuno a. Pathogens. 2020 Oct 8;9(10):825. doi: 10.3390/pathogens9100825. Pathogens. 2020. PMID: 33050033 Free PMC article.

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Lactococcus lactis subsp. Cremoris C60 restores T Cell Population in Small Intestinal Lamina Propria in Aged Interleukin-18 Deficient Mice.

Saito S, Kakizaki N, Okuno A, Maekawa T, Tsuji NM. Saito S, et al. Among authors: okuno a. Nutrients. 2020 Oct 27;12(11):3287. doi: 10.3390/nu12113287. Nutrients. 2020. PMID: 33121026 Free PMC article.

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New Inhibitors of Indoleamine 2,3-Dioxygenase 1: Molecular Modeling Studies, Synthesis, and Biological Evaluation.

Coluccia A, Passacantilli S, Famiglini V, Sabatino M, Patsilinakos A, Ragno R, Mazzoccoli C, Sisinni L, Okuno A, Takikawa O, Silvestri R, La Regina G. Coluccia A, et al. Among authors: okuno a. J Med Chem. 2016 Nov 10;59(21):9760-9773. doi: 10.1021/acs.jmedchem.6b00718. Epub 2016 Oct 26. J Med Chem. 2016. PMID: 27690429

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Dietary intake of the citrus flavonoid hesperidin affects stress-resilience and brain kynurenine levels in a subchronic and mild social defeat stress model in mice.

Sato M, Okuno A, Suzuki K, Ohsawa N, Inoue E, Miyaguchi Y, Toyoda A. Sato M, et al. Among authors: okuno a. Biosci Biotechnol Biochem. 2019 Sep;83(9):1756-1765. doi: 10.1080/09168451.2019.1621152. Epub 2019 May 23. Biosci Biotechnol Biochem. 2019. PMID: 31119994

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Differential Effect of Non-Purified and Semi-Purified Standard Diets on Kynurenine and Peripheral Metabolites in Male C57BL/6J Mice.

Yajima Y, Okuno A, Nakamura I, Miyazaki T, Honda A, Toyoda A. Yajima Y, et al. Among authors: okuno a. Int J Tryptophan Res. 2022 Jan 4;15:11786469211066285. doi: 10.1177/11786469211066285. eCollection 2022. Int J Tryptophan Res. 2022. PMID: 35002254 Free PMC article.

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Indoleamine-2,3-dioxygenase as an effector and an indicator of protective immune responses in patients with acute hepatitis B.

Yoshio S, Sugiyama M, Shoji H, Mano Y, Mita E, Okamoto T, Matsuura Y, Okuno A, Takikawa O, Mizokami M, Kanto T. Yoshio S, et al. Among authors: okuno a. Hepatology. 2016 Jan;63(1):83-94. doi: 10.1002/hep.28282. Epub 2015 Nov 23. Hepatology. 2016. PMID: 26458241

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NMR-based metabolomics of urine in a mouse model of Alzheimer's disease: identification of oxidative stress biomarkers.

Fukuhara K, Ohno A, Ota Y, Senoo Y, Maekawa K, Okuda H, Kurihara M, Okuno A, Niida S, Saito Y, Takikawa O. Fukuhara K, et al. Among authors: okuno a. J Clin Biochem Nutr. 2013 Mar;52(2):133-8. doi: 10.3164/jcbn.12-118. Epub 2013 Mar 1. J Clin Biochem Nutr. 2013. PMID: 23526113 Free PMC article.

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High tryptophan diet reduces extracellular dopamine release via kynurenic acid production in rat striatum.

Okuno A, Fukuwatari T, Shibata K. Okuno A, et al. J Neurochem. 2011 Sep;118(5):796-805. doi: 10.1111/j.1471-4159.2011.07369.x. Epub 2011 Jul 21. J Neurochem. 2011. PMID: 21711351 Free article.

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