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IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.
Van den Eynde A, Gehrcken L, Verhezen T, Lau HW, Hermans C, Lambrechts H, Flieswasser T, Quatannens D, Roex G, Zwaenepoel K, Marcq E, Joye P, Cardenas De La Hoz E, Deben C, Gasparini A, Montay-Gruel P, Le Compte M, Lion E, Lardon F, Van Laere S, Siozopoulou V, Campillo-Davo D, De Waele J, Pauwels P, Jacobs J, Smits E, Van Audenaerde JRM. Van den Eynde A, et al. Among authors: gasparini a. J Hematol Oncol. 2024 Feb 9;17(1):8. doi: 10.1186/s13045-024-01525-w. J Hematol Oncol. 2024. PMID: 38331849 Free PMC article.
Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors.
Barazas M, Gasparini A, Huang Y, Küçükosmanoğlu A, Annunziato S, Bouwman P, Sol W, Kersbergen A, Proost N, de Korte-Grimmerink R, van de Ven M, Jonkers J, Borst GR, Rottenberg S. Barazas M, et al. Among authors: gasparini a. Cancer Res. 2019 Feb 1;79(3):452-460. doi: 10.1158/0008-5472.CAN-18-2077. Epub 2018 Dec 10. Cancer Res. 2019. PMID: 30530501 Free PMC article.
Point scintillator dosimetry in ultra-high dose rate electron "FLASH" radiation therapy: A first characterization.
Vanreusel V, Gasparini A, Galante F, Mariani G, Pacitti M, Cociorb M, Giammanco A, Reniers B, Reulens N, Shonde TB, Vallet H, Vandenbroucke D, Peeters M, Leblans P, Ma B, Felici G, Verellen D, de Freitas Nascimento L. Vanreusel V, et al. Among authors: gasparini a. Phys Med. 2022 Nov;103:127-137. doi: 10.1016/j.ejmp.2022.10.005. Epub 2022 Oct 24. Phys Med. 2022. PMID: 36302279
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