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Cardiovascular Risk Reduction with Icosapent Ethyl for Hypertriglyceridemia.
Bhatt DL, Steg PG, Miller M, Brinton EA, Jacobson TA, Ketchum SB, Doyle RT Jr, Juliano RA, Jiao L, Granowitz C, Tardif JC, Ballantyne CM; REDUCE-IT Investigators. Bhatt DL, et al. N Engl J Med. 2019 Jan 3;380(1):11-22. doi: 10.1056/NEJMoa1812792. Epub 2018 Nov 10. N Engl J Med. 2019. PMID: 30415628 Clinical Trial.
Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742).
Ma BBY, Lim WT, Goh BC, Hui EP, Lo KW, Pettinger A, Foster NR, Riess JW, Agulnik M, Chang AYC, Chopra A, Kish JA, Chung CH, Adkins DR, Cullen KJ, Gitlitz BJ, Lim DW, To KF, Chan KCA, Lo YMD, King AD, Erlichman C, Yin J, Costello BA, Chan ATC. Ma BBY, et al. J Clin Oncol. 2018 May 10;36(14):1412-1418. doi: 10.1200/JCO.2017.77.0388. Epub 2018 Mar 27. J Clin Oncol. 2018. PMID: 29584545 Free PMC article. Clinical Trial.
Cost Effectiveness of Chimeric Antigen Receptor T-Cell Therapy in Relapsed or Refractory Pediatric B-Cell Acute Lymphoblastic Leukemia.
Lin JK, Lerman BJ, Barnes JI, Boursiquot BC, Tan YJ, Robinson AQL, Davis KL, Owens DK, Goldhaber-Fiebert JD. Lin JK, et al. J Clin Oncol. 2018 Nov 10;36(32):3192-3202. doi: 10.1200/JCO.2018.79.0642. Epub 2018 Sep 13. J Clin Oncol. 2018. PMID: 30212291
PURPOSE: The anti-CD19 chimeric antigen receptor T-cell therapy tisagenlecleucel was recently approved to treat relapsed or refractory pediatric acute lymphoblastic leukemia. ...
PURPOSE: The anti-CD19 chimeric antigen receptor T-cell therapy tisagenlecleucel was recently approved to treat relapsed or refractor …
Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study.
Swann OV, Holden KA, Turtle L, Pollock L, Fairfield CJ, Drake TM, Seth S, Egan C, Hardwick HE, Halpin S, Girvan M, Donohue C, Pritchard M, Patel LB, Ladhani S, Sigfrid L, Sinha IP, Olliaro PL, Nguyen-Van-Tam JS, Horby PW, Merson L, Carson G, Dunning J, Openshaw PJM, Baillie JK, Harrison EM, Docherty AB, Semple MG; ISARIC4C Investigators. Swann OV, et al. BMJ. 2020 Aug 27;370:m3249. doi: 10.1136/bmj.m3249. BMJ. 2020. PMID: 32960186 Free PMC article.
Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.
Knight SR, Ho A, Pius R, Buchan I, Carson G, Drake TM, Dunning J, Fairfield CJ, Gamble C, Green CA, Gupta R, Halpin S, Hardwick HE, Holden KA, Horby PW, Jackson C, Mclean KA, Merson L, Nguyen-Van-Tam JS, Norman L, Noursadeghi M, Olliaro PL, Pritchard MG, Russell CD, Shaw CA, Sheikh A, Solomon T, Sudlow C, Swann OV, Turtle LC, Openshaw PJ, Baillie JK, Semple MG, Docherty AB, Harrison EM; ISARIC4C investigators. Knight SR, et al. BMJ. 2020 Sep 9;370:m3339. doi: 10.1136/bmj.m3339. BMJ. 2020. PMID: 32907855 Free article.
Predicting Adverse Drug Effects from Literature- and Database-Mined Assertions.
La MK, Sedykh A, Fourches D, Muratov E, Tropsha A. La MK, et al. Drug Saf. 2018 Nov;41(11):1059-1072. doi: 10.1007/s40264-018-0688-5. Drug Saf. 2018. PMID: 29876834 Free PMC article.
Based on these assertions, a C-T-E relationship knowledge base was developed. Known pairwise relationships between chemicals, targets, and ADEs were collected from several pharmacological and biomedical data sources. These relationships were curated and integrated accordin …
Based on these assertions, a C-T-E relationship knowledge base was developed. Known pairwise relationships between chemicals, targets …
Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.
Belson A, Schmidt T, Fernando D, Hardes K, Scott N, Brett S, Clark D, Oliveira JJ, Davis B, McHugh S, Stone J. Belson A, et al. Inflamm Res. 2016 May;65(5):389-404. doi: 10.1007/s00011-016-0923-4. Epub 2016 Mar 11. Inflamm Res. 2016. PMID: 26969026 Clinical Trial.
Use of the T cell activation marker LAG-3 demonstrated the activated phenotype of these cells. ...Analysis of blister T cell subpopulations revealed some differences in phenotypes between the time points and between the CD4 and CD8 T cells. ...
Use of the T cell activation marker LAG-3 demonstrated the activated phenotype of these cells. ...Analysis of blister T cell s …
Proceedings of the 3rd Biennial Conference of the Society for Implementation Research Collaboration (SIRC) 2015: advancing efficient methodologies through community partnerships and team science : Seattle, WA, USA. 24-26 September 2015.
Lewis C, Darnell D, Kerns S, Monroe-DeVita M, Landes SJ, Lyon AR, Stanick C, Dorsey S, Locke J, Marriott B, Puspitasari A, Dorsey C, Hendricks K, Pierson A, Fizur P, Comtois KA, Palinkas LA, Chamberlain P, Aarons GA, Green AE, Ehrhart MG, Trott EM, Willging CE, Fernandez ME, Woolf NH, Liang SL, Heredia NI, Kegler M, Risendal B, Dwyer A, Young V, Campbell D, Carvalho M, Kellar-Guenther Y, Damschroder LJ, Lowery JC, Ono SS, Carlson KF, Cottrell EK, O’Neil ME, Lovejoy TL, Arch JJ, Mitchell JL, Lewis CC, Marriott BR, Scott K, Coldiron JS, Bruns EJ, Hook AN, Graham BC, Jordan K, Hanson RF, Moreland A, Saunders BE, Resnick HS, Stirman SW, Gutner CA, Gamarra J, Vogt D, Suvak M, Wachen JS, Dondanville K, Yarvis JS, Mintz J, Peterson AL, Borah EV, Litz BT, Molino A, McCaughan SY, Resick PA, Pandhi N, Jacobson N, Serrano N, Hernandez A, Schreiter EZ, Wietfeldt N, Karp Z, Pullmann MD, Lucenko B, Pavelle B, Uomoto JA, Negrete A, Cevasco M, Kerns SEU, Franks RP, Bory C, Miech EJ, Damush TM, Satterfield J, Satre D, Wamsley M, Yuan P, O’Sullivan P, Best H, Velasquez S, Barnett M, Brookman-Frazee L, Regan J, Stadnick N, Hamilton A, Lau A, Regan J, Hamilton A, Stadnick N, Barnett M, Lau A, Brookman-Frazee L, Stadnick N, Lau A, Barnett M, Regan J, Roesch S, Brookman-Frazee L, Powell BJ, Waltz TJ, Chinman MJ, Damschroder L, Smith JL, Matthieu MM, Proctor EK, Kirchner JE, Waltz TJ, Powell BJ, Chinman MJ, Damschroder LJ, Smith JL, Matthieu MJ, Proctor EK, Kirchner JE, Matthieu MM, Rosen CS, Waltz TJ, Powell BJ, Chinman MJ, Damschroder LJ, Smith JL, Proctor EK, Kirchner JE, Walker SC, Bishop AS, Lockhart M, Rodriguez AL, Manfredi L, Nevedal A, Rosenthal J, Blonigen DM, Mauricio AM, Dishion TD, Rudo-Stern J, Smith JD, Locke J, Wolk CB, Harker C, Olsen A, Shingledecker T, Barg F, Mandell D, Beidas RS, Hansen MC, Aranda MP, Torres-Vigil I, Hartzler B, Steinfeld B, Gildred T, Harlin Z, Shephard F, Ditty MS, Doyle A, Bickel JA III, Cristaudo K, Fox D, Combs S, Lischner DH, Van Dorn RA, Tueller SJ, Hinde JM, Karuntzos GT, Monroe-DeVita M, Peterson R, Darnell D, Berliner L, Dorsey S, Murray LK, Botanov Y, Kikuta B, Chen T, Navarro-Haro M, DuBose A, Korslund KE, Linehan MM, Harker CM, Karp EA, Edmunds SR, Ibañez LV, Stone WL, Andrews JH, Johnides BD, Hausman EM, Hawley KM, Prusaczyk B, Ramsey A, Baumann A, Colditz G, Proctor EK, Botanov Y, Kikuta B, Chen T, Navarro-Haro M, DuBose A, Korslund KE, Linehan MM, Harker CM, Karp EA, Edmunds SR, Ibañez LV, Stone WL, Choy-Brown M, Andrews JH, Johnides BD, Hausman EM, Hawley KM, Prusaczyk B, Ramsey A, Baumann A, Colditz G, Proctor EK, Meza RD, Dorsey S, Wiltsey-Stirman S, Sedlar G, Lucid L, Dorsey C, Marriott B, Zounlome N, Lewis C, Gutner CA, Monson CM, Shields N, Mastlej M, Landy MSH, Lane J, Stirman SW, Finn NK, Torres EM, Ehrhart MG, Aarons GA, Malte CA, Lott A, Saxon AJ, Boyd M, Scott K, Lewis CC, Pierce JD, Lorthios-Guilledroit A, Richard L, Filiatrault J, Hallgren K, Crotwell S, Muñoz R, Gius B, Ladd B, McCrady B, Epstein E, Clapp JD, Ruderman DE, Barwick M, Barac R, Zlotkin S, Salim L, Davidson M, Bunger AC, Powell BJ, Robertson HA, Botsko C, Landes SJ, Smith BN, Rodriguez AL, Trent LR, Matthieu MM, Powell BJ, Proctor EK, Harned MS, Navarro-Haro M, Korslund KE, Chen T, DuBose A, Ivanoff A, Linehan MM, Garcia AR, Kim M, Palinkas LA, Snowden L, Landsverk J, Sweetland AC, Fernandes MJ, Santos E, Duarte C, Kritski A, Krawczyk N, Nelligan C, Wainberg ML, Aarons GA, Sommerfeld DH, Chi B, Ezeanolue E, Sturke R, Kline L, Guay L, Siberry G, Bennett IM, Beidas R, Gold R, Mao J, Powers D, Vredevoogd M, Unutzer J, Schroeder J, Volpe L, Steffen J, Dorsey S, Pullmann MD, Kerns SEU, Jungbluth N, Berliner L, Thompson K, Segell E, McGee-Vincent P, Liu N, Walser R, Runnals J, Shaw RK, Landes SJ, Rosen C, Schmidt J, Calhoun P, Varkovitzky RL, Landes SJ, Drahota A, Martinez JI, Brikho B, Meza R, Stahmer AC, Aarons GA, Williamson A, Rubin RM, Powell BJ, Hurford MO, Weaver SL, Beidas RS, Mandell DS, Evans AC, Powell BJ, Beidas RS, Rubin RM, Stewart RE, Wolk CB, Matlin SL, Weaver S, Hurford MO, Evans AC, Hadley TR, Mandell DS, Gerke DR, Prusaczyk B, Baumann A, Lewis EM, Proctor EK, McWilliam J, Brown J, Tucker M, Conte KP, Lyon AR, Boyd M, Melvin A, Lewis CC, Liu F, Jungbluth N, Kotte A, Hill KA, Mah AC, Korathu-Larson PA, Au JR, Izmirian S, Keir S, Nakamura BJ, Higa-McMillan CK, Cooper BR, Funaiole A, Dizon E, Hawkins EJ, Malte CA, Hagedorn HJ, Berger D, Frank A, Lott A, Achtmeyer CE, Mariano AJ, Saxon AJ, Wolitzky-Taylor K, Rawson R, Ries R, Roy-Byrne P, Craske M, Simmons D, Torrente C, Nathanson L, Carroll G, Smith JD, Brown K, Ramos K, Thornton N, Dishion TJ, Stormshak EA, Shaw DS, Wilson MN, Choy-Brown M, Tiderington E, Smith BT, Padgett DK, Rubin RM, Ray ML, Wandersman A, Lamont A, Hannah G, Alia KA, Hurford MO, Evans AC, Saldana L, Schaper H, Campbell M, Chamberlain P, Shapiro VB, Kim BKE, Fleming JL, LeBuffe PA, Landes SJ, Lewis CC, Rodriguez AL, Marriott BR, Comtois KA, Lewis CC, Stanick C, Weiner BJ, Halko H, Dorsey C. Lewis C, et al. Implement Sci. 2016 Jun 23;11 Suppl 1(Suppl 1):85. doi: 10.1186/s13012-016-0428-0. Implement Sci. 2016. PMID: 27357964 Free PMC article.
Results from a new simulation methodology Richard A. Van Dorn, Stephen J. Tueller, Jesse M. Hinde, Georgia T. Karuntzos A36: Taking global local: Evaluating training of Washington State clinicians in a modularized cogntive behavioral therapy approach designed for low-resou …
Results from a new simulation methodology Richard A. Van Dorn, Stephen J. Tueller, Jesse M. Hinde, Georgia T. Karuntzos A36: Taking g …
Afri-Can Forum 2 : Johannesburg, South Africa. 16-18 February 2015.
Mukudu H, Martinson N, Sartorius B, Coetzee J, Dietrich J, Mokgatswana K, Jewkes R, Gray GE, Dugas M, Béhanzin L, Guédou FA, Gagnon MP, Alary M, Rutakumwa R, Mbonye M, Kiwanuka T, Nakamanya S, Muhumuza R, Nalukenge W, Seeley J, Atujuna M, Wallace M, Brown B, Bekker LG, Newman PA, Harryparsad R, Olivier AJ, Jaspan HB, Wilson D, Dietrich J, Martinson N, Mukudu H, Mkhize N, Morris L, Cianci G, Dinh M, Hope T, Passmore JAS, Gray CM, Henrick BM, Yao XD, Rosenthal KL; the INFANT Study Team, Henrick BM, Yao XD, Drannik AG, Abimiku A, Rosenthal KL; the INFANT Study Team, Chanzu N, Mwanda W, Oyugi J, Anzala O, Mbow M, Jallow S, Thiam M, Davis A, Diouf A, Ndour CT, Seydi M, Dieye TN, Mboup S, Goodier M, Rilley E, Jaye A, Yao XD, Omange RW, Henrick BM, Lester RT, Kimani J, Ball TB, Plummer FA, Rosenthal KL, Béhanzin L, Guédou FA, Geraldo N, Mastétsé EG, Sossa JC, Zannou MD, Alary M, Osawe S, Okpokoro E, Okolo F, Umaru S, Abimiku R, Audu S, Datong P, Abimiku A, Nyange J, Olenja J, Mutua G, Jaoko W, Omosa-Manyonyi G, Farah B, Khaniri M, Anzala O, Cockcroft A, Tonkin K, Girish I, Mhati P, Cunningham A, Andersson N, Farah B, Indangasi J, Jaoko W, Mutua G, Khaniri M, Nyange J, Anzala O, Diphoko T, Gaseitsiwe S, Maiswe V, Iketleng T, Maruapula D, Bedi K, Moyo S, Musonda R, Wainberg M, Makhema J, Novitsky V, Marlink R, Essex M, Okoboi S, Ssali L, Kalibala S, Birungi J, Egessa A, Wangisi J, Okullu LJ, Bakanda C, Obare F, Boer IMSD, Semvua HH, van den Boogaard J, Kiwango KW, Ngowi KM, Nieuwkerk PT, Aarnoutse RE, Kiwelu I, Muro E, Kibiki GS, Datiri R, Choji G, Osawe S, Okpokoro E, Okolo F, Umaru S, Abimiku R, Audu S, Datong P, Abimiku A, Fomsgaard A, Karlsson I, Jensen KJ, Jensen SS, Leo-Hansen C, Jespersen S, Da Silva Té D, Rodrigues CM, da Silva ZJ, Janitzek CM, Gerstoft J, Kronborg G; the WAPHIR Group, Okpokoro E, Osawe S, Daitiri R, Choji G, Umaru S, Okolo F, Datong P, Abimiku A, Emily N, Joyce O, Robert LR, Anzala A, Viljoen K, Wendoh J, Kidzeru E, Karaoz U, Brodie E, Botha G, Mulder N, Gray C, Cameron W, Stintzi A, Jaspan H; for the INFANT study team, Levett PN, Alexander D, Gulzar N, Grewal PS, Poon AFY, Brumme Z, Harrigan PR, Brooks JI, Sandstrom PA, Calvez S, Sanche SE, Scott JK, Swartz L, Kagee A, Lesch A, Kafaar Z, De Wet A, Okpokoro E, Osawe S, Daitiri R, Choji G, Umaru S, Okolo F, Datong P, Abimiku A, Dietrich J, Smith T, Cotton L, Hornschuh S, van der Watt M, Miller CL, Gray G, Smit J, Jaggernath M, Ndung’u T, Brockman M, Kaida A; on behalf of the AYAZAZI study teams, Akolo M, Kimani J, Gelmon L, Chitwa M, Osero J, Cockcroft A, Marokoane N, Kgakole L, Maswabi B, Mpofu N, Ansari U, Andersson N, Nakinobe E, Miiro GM, Zalwango F, Nakiyingi-Miiro J, Kaleebu P, Semwanga JR, Nyanzi E, Musoke SN, Nakinobe E, Miiro G, Mbidde EK, Lutalo T, Kaleebu P, Handema R, Chianzu GP, Thiam M, Diagne-Gueye D, Ndiaye MK, Mbow M, Ndiaye BP, Traore I, Dia MC, Thomas G, Tour-Kane C, Mboup S, Jaye A, Nyanzi E, Mbidde EK, Kaleebu P, Mpendo J, Kimani J, Birungi J, Muyindike W, Kambugu A, Sebastian H, Ray H, Mike C, Bertin KJ, Modest M, Thiam M, Janha O, Davis A, Amambua-Ngwa A, Nwakanma DC, Mboup S, Jaye A, Jespersen S, Hønge BL, Esbjörnsson J, Medina C, Da Silva TÉ D, Correira FG, Laursen AL, Østergaard L, Andersen A, Aaby P, Erikstrup C, Wejse C; for the Bissau HIV Cohort study group, Dieye S, Sarr M, Sy H, Mbodj HD, Ndiaye M, Ndiaye A, Moussa S, Jaye A, Mboup S, Nyombi BM, Shao ER, Chilumba IB, Moyo S, Gaseitsiwe S, Musonda R, Datong P, Inyang B, Osawe S, Izang A, Cole C, Okolo F, Cameron B, Rosenthal K, Gray C, Jaspan H, Abimiku A; the INFANT study team, Seraise B, Andrea-Marobela K, Moyo S, Musonda R, Makhema J, Essex M, Gaseitsiwe S. Mukudu H, et al. BMC Infect Dis. 2016 Jul 12;16 Suppl 2(Suppl 2):315. doi: 10.1186/s12879-016-1466-6. BMC Infect Dis. 2016. PMID: 27410689 Free PMC article.
Omange, Bethany M. Henrick, Richard T. Lester, Joshua Kimani, T. Blake Ball, Francis A. Plummer, Kenneth L. ...Semvua, Jossy van den Boogaard, Krisanta W. Kiwango, Kennedy M. Ngowi, Pythia T. Nieuwkerk, Rob E. Aarnoutse, Ireen Kiwelu, Eva Muro, Gibson S. ...
Omange, Bethany M. Henrick, Richard T. Lester, Joshua Kimani, T. Blake Ball, Francis A. Plummer, Kenneth L. ...Semvua, Jossy v …
Low rates of pregnancy screening in adolescents before teratogenic exposures in a national sample of children's hospitals.
Rao P, Li Y, Getz KD, Miller TP, Huang YS, Wilkes JJ, Seif AE, Bagatell R, Fisher BT, Gracia C, Aplenc R. Rao P, et al. Cancer. 2016 Nov 15;122(21):3394-3400. doi: 10.1002/cncr.30225. Epub 2016 Sep 12. Cancer. 2016. PMID: 27618636 Free PMC article.
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