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Showing results for Alexander D. steady
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Patient Variables Associated with Nafcillin Plasma Concentrations and Toxicity.
Benefield RJ, Barker BC, Gast CM, Alexander DP. Benefield RJ, et al. Among authors: alexander dp. Pharmacotherapy. 2016 Sep;36(9):994-1002. doi: 10.1002/phar.1805. Epub 2016 Sep 1. Pharmacotherapy. 2016. PMID: 27485941
METHODS: Retrospective chart review of patients receiving nafcillin via continuous infusion at University of Utah Health Care from 2006 to 2013 who had at least one steady-state CNAF measured. CLNAF was determined by dividing the nafcillin rate of infusion by CNAF . ...
METHODS: Retrospective chart review of patients receiving nafcillin via continuous infusion at University of Utah Health Care from 2006 to 2 …
An optimized framework for quantitative magnetization transfer imaging of the cervical spinal cord in vivo.
Battiston M, Grussu F, Ianus A, Schneider T, Prados F, Fairney J, Ourselin S, Alexander DC, Cercignani M, Gandini Wheeler-Kingshott CAM, Samson RS. Battiston M, et al. Among authors: alexander dc. Magn Reson Med. 2018 May;79(5):2576-2588. doi: 10.1002/mrm.26909. Epub 2017 Sep 16. Magn Reson Med. 2018. PMID: 28921614 Free PMC article.
RESULTS: Cramer-Rao-lower bound minimization produces optimal sampling schemes without requiring the establishment of a steady-state MT effect. The proposed framework allows quantitative voxel-wise estimation of model parameters at the resolution typically used for spinal …
RESULTS: Cramer-Rao-lower bound minimization produces optimal sampling schemes without requiring the establishment of a steady-state …
Detrimental effects of adenosine signaling in sickle cell disease.
Zhang Y, Dai Y, Wen J, Zhang W, Grenz A, Sun H, Tao L, Lu G, Alexander DC, Milburn MV, Carter-Dawson L, Lewis DE, Zhang W, Eltzschig HK, Kellems RE, Blackburn MR, Juneja HS, Xia Y. Zhang Y, et al. Among authors: alexander dc. Nat Med. 2011 Jan;17(1):79-86. doi: 10.1038/nm.2280. Epub 2010 Dec 19. Nat Med. 2011. PMID: 21170046 Free PMC article.
Many factors and metabolites are altered in response to hypoxia and may contribute to the pathogenesis of the disease. Using metabolomic profiling, we found that the steady-state concentration of adenosine in the blood was elevated in a transgenic mouse model of SCD. ...
Many factors and metabolites are altered in response to hypoxia and may contribute to the pathogenesis of the disease. Using metabolomic pro …
Human safety and pharmacokinetics of the CFC alternative propellants HFC 134a (1,1,1,2-tetrafluoroethane) and HFC 227 (1,1,1,2,3,3, 3-heptafluoropropane) following whole-body exposure.
Emmen HH, Hoogendijk EM, Klöpping-Ketelaars WA, Muijser H, Duistermaat E, Ravensberg JC, Alexander DJ, Borkhataria D, Rusch GM, Schmit B. Emmen HH, et al. Among authors: alexander dj. Regul Toxicol Pharmacol. 2000 Aug;32(1):22-35. doi: 10.1006/rtph.2000.1402. Regul Toxicol Pharmacol. 2000. PMID: 11029265 Clinical Trial.
HFC 134a, HFC 227, and CFC 12 blood concentrations increased rapidly and in an exposure-concentration-dependent manner, although not strictly proportionally, and approached steady state. Maximum blood concentrations (C(max)) tended to be higher in males than females; in th …
HFC 134a, HFC 227, and CFC 12 blood concentrations increased rapidly and in an exposure-concentration-dependent manner, although not strictl …
Cefmenoxime pharmacokinetics in healthy volunteers and subjects with renal insufficiency and on hemodialysis.
Gambertoglio JG, Alexander DP, Barriere SL. Gambertoglio JG, et al. Among authors: alexander dp. Antimicrob Agents Chemother. 1984 Dec;26(6):845-9. doi: 10.1128/AAC.26.6.845. Antimicrob Agents Chemother. 1984. PMID: 6098220 Free PMC article.
Plasma clearance declined in patients with renal insufficiency and correlated significantly with creatine clearance. The mean apparent volume of distribution at steady state in the healthy volunteers was 0.23 liters/kg and was not found to be significantly different in sub …
Plasma clearance declined in patients with renal insufficiency and correlated significantly with creatine clearance. The mean apparent volum …
The fluorescence study of the binding of zinc phthalocyanine to breast cancer cells solubilized in synthetic liposomes.
Iwunze MO, Alexander D. Iwunze MO, et al. Among authors: alexander d. Cell Mol Biol (Noisy-le-grand). 2001 Sep;47(6):1047-50. Cell Mol Biol (Noisy-le-grand). 2001. PMID: 11785655
Steady state fluorescence spectroscopy is used to study the binding characteristics of zinc phthalocyanine (ZnPc) to MCF-7 human breast cancer cells solubilized in a liposomal vesicle prepared with L-alpha-phosphatidic acid, dipalmitoyl. ...
Steady state fluorescence spectroscopy is used to study the binding characteristics of zinc phthalocyanine (ZnPc) to MCF-7 human brea
Normalized lift: an energy interpretation of the lift coefficient simplifies comparisons of the lifting ability of rotating and flapping surfaces.
Burgers P, Alexander DE. Burgers P, et al. Among authors: alexander de. PLoS One. 2012;7(5):e36732. doi: 10.1371/journal.pone.0036732. Epub 2012 May 21. PLoS One. 2012. PMID: 22629326 Free PMC article.
Because the lift coefficient was developed initially for fixed wings in steady flow, its application to other lifting systems requires either simplifying assumptions or complex adjustments as is the case for flapping wings and rotating cylinders.This paper interprets the s …
Because the lift coefficient was developed initially for fixed wings in steady flow, its application to other lifting systems require …
Analysis of allogeneic and syngeneic rat heart transplants using 23Na magnetic resonance spectroscopy.
Waldrop SM, Alexander DZ, Lowry R, Winn KJ, Pearson TC, Constantinidis I. Waldrop SM, et al. Among authors: alexander dz. Biochem Biophys Res Commun. 1996 Jun 14;223(2):379-83. doi: 10.1006/bbrc.1996.0902. Biochem Biophys Res Commun. 1996. PMID: 8670290
Allogeneic hearts showed cellular rejection by Day 1. 23Na MRS showed a steady elevation in signal in the 3 days prior to rejection and a sharp rise after rejection. 23Na MRS accurately identified full rejection and was also sensitive to the rejection process....
Allogeneic hearts showed cellular rejection by Day 1. 23Na MRS showed a steady elevation in signal in the 3 days prior to rejection a …
Pharmacokinetic disposition of cefonicid in patients with renal failure and receiving hemodialysis.
Barriere SL, Gambertoglio JG, Alexander DP, Stagg RJ, Conte JE Jr. Barriere SL, et al. Among authors: alexander dp. Rev Infect Dis. 1984 Nov-Dec;6 Suppl 4:S809-15. doi: 10.1093/clinids/6.supplement_4.s809. Rev Infect Dis. 1984. PMID: 6522922
Total clearance and renal clearance decreased linearly with decreases in creatinine clearance. Steady-state volume of distribution remained approximately the same (0.11 liter/kg) in all patients. ...
Total clearance and renal clearance decreased linearly with decreases in creatinine clearance. Steady-state volume of distribution re …