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Early non-invasive ventilation and high-flow nasal oxygen therapy for preventing endotracheal intubation in hypoxemic blunt chest trauma patients: the OptiTHO randomized trial.
Carrié C, Rieu B, Benard A, Trin K, Petit L, Massri A, Jurcison I, Rousseau G, Tran Van D, Reynaud Salard M, Bourenne J, Levrat A, Muller L, Marie D, Dahyot-Fizelier C, Pottecher J, David JS, Godet T, Biais M. Carrié C, et al. Crit Care. 2023 Apr 26;27(1):163. doi: 10.1186/s13054-023-04429-2. Crit Care. 2023. PMID: 37101272 Free PMC article. Clinical Trial.
The primary objective was to compare the rate of endotracheal intubation for delayed respiratory failure between two NIV strategies: i) a prompt association of HFNC-O(2) and "early" NIV in every patient for at least 48 h with vs. ii) the standard of care associating COT an …
The primary objective was to compare the rate of endotracheal intubation for delayed respiratory failure between two NIV strategies: i) a pr …