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The following term was not found in PubMed: Marchoud
Page 1
Did you mean amine marchou (1 results)?
Amine coupling through EDC/NHS: a practical approach.
Fischer MJ. Fischer MJ. Methods Mol Biol. 2010;627:55-73. doi: 10.1007/978-1-60761-670-2_3. Methods Mol Biol. 2010. PMID: 20217613
The most common technique for linking ligands covalently to a hydrophilic solid surface is amine coupling via reactive esters. In this chapter detailed methods and problem discussions will be given to assist in fast decision analysis to optimize immobilization and regenera …
The most common technique for linking ligands covalently to a hydrophilic solid surface is amine coupling via reactive esters. In thi …
Reductive Amination in the Synthesis of Pharmaceuticals.
Afanasyev OI, Kuchuk E, Usanov DL, Chusov D. Afanasyev OI, et al. Chem Rev. 2019 Dec 11;119(23):11857-11911. doi: 10.1021/acs.chemrev.9b00383. Epub 2019 Oct 21. Chem Rev. 2019. PMID: 31633341 Review.
Reductive amination plays a paramount role in pharmaceutical and medicinal chemistry owing to its synthetic merits and the ubiquitous presence of amines among biologically active compounds. ...Recent studies show that at least a quarter of C-N bond-forming reactions …
Reductive amination plays a paramount role in pharmaceutical and medicinal chemistry owing to its synthetic merits and the ubiquitous …
Unprotected amine transfer performed by non-heme iron(II) complexes.
Boullé A, Doumbia A, Mahy JP, Avenier F. Boullé A, et al. Chem Commun (Camb). 2022 Dec 22;59(1):79-81. doi: 10.1039/d2cc04992a. Chem Commun (Camb). 2022. PMID: 36468296
Direct amination of C-H or CC bonds using unprotected amino groups is very challenging, especially with earth abundant metal ions. Here we show that a bioinspired iron(II) complex catalyses the double amination of its dangling benzyl branch in the presence of hydrox …
Direct amination of C-H or CC bonds using unprotected amino groups is very challenging, especially with earth abundant metal ions. He …
Synthesis of chiral amines using redox biocatalysis.
Grogan G. Grogan G. Curr Opin Chem Biol. 2018 Apr;43:15-22. doi: 10.1016/j.cbpa.2017.09.008. Epub 2017 Oct 31. Curr Opin Chem Biol. 2018. PMID: 29100099 Free article. Review.
Chiral amines feature in a large number of small molecule pharmaceuticals, and thus methods for their asymmetric synthesis are of considerable interest. ...Advances in redox cofactor process technology have meant that oxidoreductase enzymes in particular now have growing p …
Chiral amines feature in a large number of small molecule pharmaceuticals, and thus methods for their asymmetric synthesis are of con …
Amine Transaminase Engineering for Spatially Bulky Substrate Acceptance.
Weiß MS, Pavlidis IV, Spurr P, Hanlon SP, Wirz B, Iding H, Bornscheuer UT. Weiß MS, et al. Chembiochem. 2017 Jun 1;18(11):1022-1026. doi: 10.1002/cbic.201700033. Epub 2017 Apr 27. Chembiochem. 2017. PMID: 28334484
Amine transaminase (ATA) catalyzing stereoselective amination of prochiral ketones is an attractive alternative to transition metal catalysis. ...The evolved ATAs perform asymmetric synthesis of the respective R amine with high conversions by using either ala
Amine transaminase (ATA) catalyzing stereoselective amination of prochiral ketones is an attractive alternative to transition
CuCl-photocatalyzed C-H amination of benzoxazoles.
Li GN, Li HC, Lu Z, Yu B. Li GN, et al. Org Biomol Chem. 2022 Jun 29;20(25):5125-5128. doi: 10.1039/d2ob00687a. Org Biomol Chem. 2022. PMID: 35704388
The direct coupling of benzoxazoles and amines was realized by visible light irradiation and CuCl catalysis. Various aminated benzoxazoles were successfully synthesized under mild conditions with air as an oxidant....
The direct coupling of benzoxazoles and amines was realized by visible light irradiation and CuCl catalysis. Various aminated
Enzymatic Nitrogen Incorporation Using Hydroxylamine.
Gao S, Das A, Alfonzo E, Sicinski KM, Rieger D, Arnold FH. Gao S, et al. J Am Chem Soc. 2023 Sep 20;145(37):20196-20201. doi: 10.1021/jacs.3c08053. Epub 2023 Sep 6. J Am Chem Soc. 2023. PMID: 37671894
Directed evolution of Pyrobaculum arsenaticum protoglobin generated efficient enzymes for benzylic C-H primary amination and styrene aminohydroxylation. Mechanistic studies supported a stepwise radical pathway involving rate-limiting hydrogen atom transfer. This unpreceden …
Directed evolution of Pyrobaculum arsenaticum protoglobin generated efficient enzymes for benzylic C-H primary amination and styrene …
Modular Two-Step Route to Sulfondiimidamides.
Zhang ZX, Bell C, Ding M, Willis MC. Zhang ZX, et al. J Am Chem Soc. 2022 Jul 6;144(26):11851-11858. doi: 10.1021/jacs.2c04404. Epub 2022 Jun 21. J Am Chem Soc. 2022. PMID: 35729783 Free PMC article.
Herein, we describe a two-step synthesis of sulfondiimidamides, exploiting a hypervalent iodine-mediated amination as the key step. The starting materials are organometallic reagents, an unsymmetrical sulfurdiimide, and amines. ...
Herein, we describe a two-step synthesis of sulfondiimidamides, exploiting a hypervalent iodine-mediated amination as the key step. T …
Recent Advances in 1,2-Amino(hetero)arylation of Alkenes.
Kwon Y, Wang Q. Kwon Y, et al. Chem Asian J. 2022 Jun 15;17(12):e202200215. doi: 10.1002/asia.202200215. Epub 2022 May 3. Chem Asian J. 2022. PMID: 35460596 Free PMC article. Review.
Next, two-component reactions will be discussed with different combination of precursors, N-tethered alkenes and external aryl precursor, C-tethered alkenes and external amine precursor, or C, N-tethered reagents, and alkenes. Last, three-component intermolecular amino(het …
Next, two-component reactions will be discussed with different combination of precursors, N-tethered alkenes and external aryl precursor, C- …
Palladium N-Heterocyclic Carbene-Catalyzed Aminations: An Outline.
Umabharathi SB, Neetha M, Anilkumar G. Umabharathi SB, et al. Top Curr Chem (Cham). 2024 Jan 24;382(1):3. doi: 10.1007/s41061-024-00449-w. Top Curr Chem (Cham). 2024. PMID: 38265533 Review.
Amination offers the potential to fine tune the properties of natural products and produce functional materials for various applications. ...This review outlines the advancements in Pd-NHC-catalyzed amination reactions, covering literature up to date....
Amination offers the potential to fine tune the properties of natural products and produce functional materials for various applicati
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