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Solid-phase supported design of carriers for therapeutic nucleic acid delivery.
Krhac Levacic A, Morys S, Wagner E. Krhac Levacic A, et al. Biosci Rep. 2017 Oct 31;37(5):BSR20160617. doi: 10.1042/BSR20160617. Print 2017 Oct 31. Biosci Rep. 2017. PMID: 28963371 Free PMC article. Review.
Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes.
Levacic AK, Morys S, Kempter S, Lächelt U, Wagner E. Levacic AK, et al. Hum Gene Ther. 2017 Oct;28(10):862-874. doi: 10.1089/hum.2017.123. Epub 2017 Aug 21. Hum Gene Ther. 2017. PMID: 28826232
Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides.
Kuhn J, Lin Y, Krhac Levacic A, Al Danaf N, Peng L, Höhn M, Lamb DC, Wagner E, Lächelt U. Kuhn J, et al. Among authors: krhac levacic a. Bioconjug Chem. 2020 Mar 18;31(3):729-742. doi: 10.1021/acs.bioconjchem.9b00853. Epub 2020 Feb 3. Bioconjug Chem. 2020. PMID: 31967454
Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer.
Kos P, Lächelt U, Herrmann A, Mickler FM, Döblinger M, He D, Krhač Levačić A, Morys S, Bräuchle C, Wagner E. Kos P, et al. Among authors: krhac levacic a. Nanoscale. 2015 Mar 12;7(12):5350-62. doi: 10.1039/c4nr06556e. Nanoscale. 2015. PMID: 25721131
Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery.
He D, Müller K, Krhac Levacic A, Kos P, Lächelt U, Wagner E. He D, et al. Among authors: krhac levacic a. Bioconjug Chem. 2016 Mar 16;27(3):647-59. doi: 10.1021/acs.bioconjchem.5b00649. Epub 2016 Jan 24. Bioconjug Chem. 2016. PMID: 26726077
Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles.
Morys S, Krhac Levacic A, Urnauer S, Kempter S, Kern S, Rädler JO, Spitzweg C, Lächelt U, Wagner E. Morys S, et al. Among authors: krhac levacic a. Polymers (Basel). 2017 Apr 19;9(4):142. doi: 10.3390/polym9040142. Polymers (Basel). 2017. PMID: 30970822 Free PMC article.
Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene.
Urnauer S, Morys S, Krhac Levacic A, Müller AM, Schug C, Schmohl KA, Schwenk N, Zach C, Carlsen J, Bartenstein P, Wagner E, Spitzweg C. Urnauer S, et al. Among authors: krhac levacic a. Mol Ther. 2016 Aug;24(8):1395-404. doi: 10.1038/mt.2016.95. Epub 2016 May 9. Mol Ther. 2016. PMID: 27157666 Free PMC article.
Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes.
Klein PM, Müller K, Gutmann C, Kos P, Krhac Levacic A, Edinger D, Höhn M, Leroux JC, Gauthier MA, Wagner E. Klein PM, et al. Among authors: krhac levacic a. J Control Release. 2015 May 10;205:109-19. doi: 10.1016/j.jconrel.2014.12.035. Epub 2014 Dec 29. J Control Release. 2015. PMID: 25553827
Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo.
Beckert L, Kostka L, Kessel E, Krhac Levacic A, Kostkova H, Etrych T, Lächelt U, Wagner E. Beckert L, et al. Among authors: krhac levacic a. Eur J Pharm Biopharm. 2016 Aug;105:85-96. doi: 10.1016/j.ejpb.2016.05.019. Epub 2016 May 25. Eur J Pharm Biopharm. 2016. PMID: 27235729
Traceless pH sensitive coating of polyplexes prepared from well-defined polycations.
Kostka L, Beckert L, Levacic AK, Etrych T, Wagner E. Kostka L, et al. Among authors: levacic ak. J Control Release. 2015 Sep 10;213:e70. doi: 10.1016/j.jconrel.2015.05.116. Epub 2015 Aug 19. J Control Release. 2015. PMID: 27005215 No abstract available.
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