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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 2
2006 4
2007 1
2008 4
2009 2
2010 4
2011 2
2012 2
2013 2
2015 3
2019 1
2020 0
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24 results
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Page 1
Prodrugs for amines.
Simplício AL, Clancy JM, Gilmer JF. Simplício AL, et al. Molecules. 2008 Mar 3;13(3):519-47. doi: 10.3390/molecules13030519. Molecules. 2008. PMID: 18463563 Free PMC article. Review.
Exploring the analytical power of the QTOF MS platform to assess monoclonal antibodies quality attributes.
Gomes RA, Almeida C, Correia C, Guerreiro A, Simplício AL, Abreu IA, Alves PG. Gomes RA, et al. PLoS One. 2019 Jul 10;14(7):e0219156. doi: 10.1371/journal.pone.0219156. eCollection 2019. PLoS One. 2019. PMID: 31291294 Free PMC article.
Peptidomimetic β-Secretase Inhibitors Comprising a Sequence of Amyloid-β Peptide for Alzheimer's Disease.
Vila-Real H, Coelho H, Rocha J, Fernandes A, Ventura MR, Maycock CD, Iranzo O, Simplício AL. Vila-Real H, et al. Among authors: simplicio al. J Med Chem. 2015 Jul 23;58(14):5408-18. doi: 10.1021/acs.jmedchem.5b00658. Epub 2015 Jul 1. J Med Chem. 2015. PMID: 26061085
A methodology for detection and quantification of esterase activity.
Simplício AL, Coroadinha AS, Gilmer JF, Lamego J. Simplício AL, et al. Methods Mol Biol. 2013;984:309-19. doi: 10.1007/978-1-62703-296-4_22. Methods Mol Biol. 2013. PMID: 23386353
Human carboxylesterase 2: Studies on the role of glycosylation for enzymatic activity.
Alves M, Lamego J, Bandeiras T, Castro R, Tomás H, Coroadinha AS, Costa J, Simplício AL. Alves M, et al. Biochem Biophys Rep. 2015 Nov 19;5:105-110. doi: 10.1016/j.bbrep.2015.11.018. eCollection 2016 Mar. Biochem Biophys Rep. 2015. PMID: 28955811 Free PMC article.
Comparison of in vitro methods for carboxylesterase activity determination in immortalized cells representative of the intestine, liver and kidney.
Lamego J, Ferreira P, Alves M, Matias A, Simplício AL. Lamego J, et al. Mol Cell Probes. 2015 Aug;29(4):215-22. doi: 10.1016/j.mcp.2015.05.002. Epub 2015 May 13. Mol Cell Probes. 2015. PMID: 25979594
Dopamine- and tyramine-based derivatives of triazenes: activation by tyrosinase and implications for prodrug design.
Perry MJ, Mendes E, Simplício AL, Coelho A, Soares RV, Iley J, Moreira R, Francisco AP. Perry MJ, et al. Eur J Med Chem. 2009 Aug;44(8):3228-34. doi: 10.1016/j.ejmech.2009.03.025. Epub 2009 Mar 27. Eur J Med Chem. 2009. PMID: 19386398
Carboxylesterase 2 production and characterization in human cells: new insights into enzyme oligomerization and activity.
Lamego J, Cunha B, Peixoto C, Sousa MF, Alves PM, Simplício AL, Coroadinha AS. Lamego J, et al. Among authors: simplicio al. Appl Microbiol Biotechnol. 2013 Feb;97(3):1161-73. doi: 10.1007/s00253-012-3994-3. Epub 2012 Mar 25. Appl Microbiol Biotechnol. 2013. PMID: 22446793
Detection and quantification of carboxylesterase 2 activity by capillary electrophoresis.
Lamego J, Coroadinha AS, Simplício AL. Lamego J, et al. Anal Chem. 2011 Feb 1;83(3):881-7. doi: 10.1021/ac102547c. Epub 2011 Jan 5. Anal Chem. 2011. PMID: 21207966
Sodium dodecyl sulfate-capillary gel electrophoresis analysis of rotavirus-like particles.
Mellado MC, Franco C, Coelho A, Alves PM, Simplício AL. Mellado MC, et al. J Chromatogr A. 2008 May 23;1192(1):166-72. doi: 10.1016/j.chroma.2008.03.035. Epub 2008 Mar 16. J Chromatogr A. 2008. PMID: 18378247
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